Top
30
Doctor insights on: False Positive Rheumatoid Factor

Share
1

1
Should I be worried if I have a false positive rheumatoid factor?

Should I be worried if I have a false positive rheumatoid factor?

Probably not: False positive rheumatoid factors are not uncommon. I am a little confused. If it is a false positive, why was it ordered in the first place? ...Read more

Dr. Chokkalingam Siva
166 Doctors shared insights

Rheumatoid Factor (Definition)

Rheumatoid factor (rf) is a test that is often sent to evaluate a person with joint pain and stiffness. A positive rf has to be interpreted in the context of the patients symptoms. Sometimes the + rf is false, and not clinically related to the patients symptoms. Rf can be +ve in other conditions such as infections and certain cancers. Some patients with rheumatoid arthritis ...Read more


2

2
What does a positive rheumatoid factor test result mean?

What does a positive rheumatoid factor test result mean?

Auto-immune response: Rheumatoid factor is one of the auto-immune responses, however, it may also develop as a some what normal respose to infection. Any lab test needs to be evaluated in the context of the whole clinical picture and a positive rheumatoid factor, by itself, is not diagnostic of any disease. It supports a diagnosis rheumatoid arthritis and other auto-immune disorders. ...Read more

4

4
What does it mean if my rheumatoid factor is positive?

See details: The rheumatoid factor is not that specific. The ccp antibody is much more specific for ra. If you have joint pain and swelling, RA is a major, but not the only possibility. ...Read more

5

5
What does a mildly positive rheumatoid factor test indicate?

It depends: A rheumatoid factor (RF) is a non-specific result. It can be positive in Rheumatoid Arthritis and a variety of other conditions. Many have a positive RF and have no disease at all (false positive). What's most important is your symptoms. Certain patterns of joint pain, stiffness and fatigue can be related to rheumatoid arthritis for example. Then the positive RF is significant. ...Read more

6

6
In lupus, can you rheumatoid factor be negative? Or is it positive?

In lupus, can you rheumatoid factor be negative? Or is it positive?

Usually negative: Anti-nuclear antibodies are almost always positive if it's really lupus. These tests are fraught with technical pitfalls, and are never more than adjuncts to a clinical diagnosis. ...Read more

7

7
Could you have a positive rheumatoid factor and a high ANA but not have any illness?

Could you have a positive rheumatoid factor and a high ANA but not have any illness?

Why have tests?: It is possible to have these lab findings and not have a disease, however, why did you have the tests done? If you have some symptoms that prompted the tests then you need be evaluated for possible auto-immune disorder. ...Read more

8

8
I went to get tested to see if I have rheumatoid arthritis and the result came back positive. What does Rheumatoid Factor H12 mean? < 10 kU/L (range)

I went to get tested to see if I have rheumatoid arthritis and the result came back positive. What does Rheumatoid Factor H12 mean? < 10 kU/L (range)

Slight elevation: This is a slight elevation of your Rheumatoid factor WHICH IS SEEN IN A LOT OF DISORDERS BESIDES heumatoid arthritis! You should see a Rheumatologist for a more complete work-up!
Hope this helps
Good Luck

Dr Z ...Read more

9

9
I got a weak positive ANA and negative rheumatoid factor. What does this mean?

They don`t mean much: These tests are within normal limits and don`t mean much. Tests can be negative in the presence of disease and positive in normal people. Diagnoses depend on a competent physician who does a proper history and physical exam and uses tests and x-rays and others to arrive at a diagnosis. Don`t over depend on tests. ...Read more

10

10
What is seronegative RA? Is that Positive Rheumatoid Factor and negative Anti CCP?

Seronegative RA: Is when the rheumatoid factor is negative, one other common type of these are referred to as seronegative spondyloarthropathies or other seronegative disorders associted with inflammatory disease. There is a wide range ...Read more

11

11
Would 176 RA IgM factor be considered a low positive for rheumatoid factor. What would be considered a positive level. My ccp level is normal.

Would 176 RA IgM factor be considered a low positive for rheumatoid factor. What would be considered a positive level. My ccp level is normal.

It is positive: The level is not as important as what is your clinical examination and other findings. The positive rheumatoid factor by itself does not mean you have arthritis. There are other things that you rheumatologist will look forward to help clarify whether the positive rheumatoid factor is due to rheumatoid arthritis or something else. ...Read more

14

14
What does a mildly positive rheumatoid factor test indicate if the doctor thinks you don't have arthritis?

There are nearly 5%: There are nearly 5% of the population with a positive rf, but only 1% has ra. Therefore 80% of rf that are positive are "false positives." most are very low in titer. A higher level of rf positivity is more significant, since level does correlate with higher disease activity in ra. Less common causes for rf positivity include sjogren's syndrome, sarcoid, and others, but these are much less common. ...Read more

19

19
Positive arthritis-joint inflammation condition but negative rheumatoid factor in blood panel. What is the reason?

Positive arthritis-joint inflammation condition but negative rheumatoid factor in blood panel. What is the reason?

Many possibilities: Even in rheumatoid arthritis, 25% of people never make rheumatoid factor. A host of joint diseases, including most juvenile rheumatoid arthritis, lupus, gout, infectious arthritis, parvo b19, chikungunya, lyme disease, hemochromatosis, alkaptonuria, reactive arthritis and psoriatic arthritis usually have no rheumatoid factor. ...Read more

20

20
I tested positive for the ANA screen, 1:160 titer, speckled pattern. Rheumatoid factor 21, SED rate 22. Does this indicate Rheumatoid arthritis?

I tested positive for the ANA screen, 1:160 titer, speckled pattern. Rheumatoid factor 21, SED rate 22. Does this indicate Rheumatoid arthritis?

No: The rheumatoid factor was barely above negative. It is usually greater than 150 in RA. The CCP antibody is a much more specific test. The diagnosis of RA depends on several diagnostic criteria. The rheumatoid factor is nonspecific. ...Read more

21

21
Hi I have had some blood tests - suspected RA, my rheumatoid factor is 241! anti-nuclear factor positive, serum c is 8mg/l and sedrate 15mm/h and platelet distribution width 15.3%, rest was ok?

Hi I have had some blood tests - suspected RA, my rheumatoid factor is 241! anti-nuclear factor positive, serum c is 8mg/l and sedrate 15mm/h and platelet distribution width 15.3%, rest was ok?

Rheumatologist: If you have not been evaluated by a rheumatologist, I recommend that you do so in view of the high RA factor and positive ANA and slightly elevated sed rate. These tests are at times nonspecific and your clinical findings have to be taken into consideration for diagnostic purposes. ...Read more

22

22
I have a positive rheumatoid factor of 69 with no inflamation but I have nodules on my fingers and a swollen knee joint, what could this be?

I have a positive rheumatoid factor of 69 with no inflamation but I have nodules on my fingers and a swollen knee joint, what could this be?

Arthritis: There are many causes of arthritis. It sounds like you have had some medical care for this before. I would recommend seeing your physician or rheumatologist for more information. ...Read more

23

23
What does rheumatoid factor mean?

What does rheumatoid factor mean?

Rheumatoid factor is: An antibody that is not normally found in the blood, so your body's production of it may indicate RA or another connective tissue disease. However, it can also be present in healthy individuals with no known disease. By contrast, according to the national institutes of health, individuals with these types of diseases can have a low rheumatoid factor or none at all. ...Read more

24

24
What does rheumatoid factor 5 mean?

Your question cannot: Can't answer your question. Rf of 5 tells me little. Rephrase it and i'll try again! ...Read more

25

25
Can there be changes in rheumatoid factor?

Depends!: If a patient has RA, RF will go down with traditional DMARD Rx: sulphasalazine, hydroxchloroquine, methotrexate. Humira and other TNF-a inhibitors do not! ...Read more

26

26
What does having high rheumatoid factor mean?

What does having high rheumatoid factor mean?

The higher more sign: The higher the titer of rf, the more likely it is a significant indicator of an automimmune disease, most likely ra. However it can be quite elevated in sarcoid, sjogren's, cryoglobulinemia, among others to name a few. A ccp antibody should be the next test obtained. If significantly positive, the DX is probably ra. ...Read more

27

27
How and when can a rheumatoid factor be produced?

Anytime: Rheumatoid factor is a protein and may be found under various circumstances. Having a positive rheumatopid factor is not synonamous with having rheumatoid arthritis. Various protein abnormalities can procduce rheumatoid factor and it may be seen in other conditions as well. ...Read more

28

28
What does it mean if my rheumatoid factor is 7060?

What does it mean if my rheumatoid factor is 7060?

High value: I am assuming you had the test done because you were having joint pain and if this is so, it looks as though you may have rheumatoid arthritis. Some patients with high values like you have may require more aggressive treatment for your joint disease. See a rheumatologist if not doing so already. ...Read more

29

29
Can you tell me how is rheumatoid factor produced?

Can you tell me how is rheumatoid factor produced?

RF!: Rheumatoid factor is present in 5% of the population, while only about 1% have rheumatoid arthritis. Rheumatoid factor is usually an igm moiety directed against the "tail" of igg! Any chronic immune stimulation, including infection, can cause a positive rf! ...Read more

30

30
What is the definition or description of: rheumatoid factor?

What is the definition or description of: rheumatoid factor?

RF assoc. With RA: Rheumatoid factor (rf) is a test that is often sent to evaluate a person with joint pain and stiffness. A positive rf has to be interpreted in the context of the patients symptoms. Sometimes the + rf is false, and not clinically related to the patients symptoms. Rf can be +ve in other conditions such as infections and certain cancers. Some patients with rheumatoid arthritis have a negative rf. ...Read more

Rheumatism (Definition)

"rheumatism" is an older term, not used much today. Most people are referring to pain and swelling in the joints when they use this term. People may mean something different when they use this term in contrast to when they refer ...Read more