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Doctor insights on: False Negative Lupus

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Can ANA test be false negative for lupus?

Can ANA test be false negative for lupus?

Lupus: Has specific criteria for diagnosis, ANA is just one of them and canot be relied on by itself for a diagnosis. ...Read more

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Please tell me, could lupus be a false negative?

Please tell me, could lupus be a false negative?

You: Mean false negative ana, yes but rare. But remember other criteria must be present for diagnosis. ...Read more

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Is it possible for lupus be cause a false negative?

No: A negative test means a negative test. If the ANA is negative, the chance of having lupus is small. ...Read more

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What is the likelihood of a false negative herpes type specific blood test with background of lupus (sle)?

What is the likelihood of a false negative herpes type specific blood test with background of lupus (sle)?

About 0% to 9%: Quest diagnostics' website states that their herpes type-specific IgG antibody test is 91-100% sensitive, so there are a few false negative results. A repeat test can be done 4-6 weeks later, if worried about a false negative. Lupus should not affect the result, but if a person is on strong immuno-suppressive therapy, his antibody production may be blocked, which may make test results unreliable. ...Read more

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I recently had a positive ANA test. My dr tested folupus but it was negative. I have all the symptoms except rash. Can u have a false neg lupus test?

I recently had a positive ANA test. My dr tested folupus but it was negative. I have all the symptoms except rash. Can u have a false neg lupus test?

Keep working: Lupus is defined by a series of criteria, of which a strongly positive ANA is one. No specific test turning out negative rules out lupus. Perhaps you were tested for anti-smith(sm), which if positive hands us the diagnosis but is only positive in 1 of 3 patients. Perhaps there is a misunderstanding or you can request consultation. Lupus requires great courage -- will be thinking of you. ...Read more

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Is there a sero negative form of lupus?

Yes: A small numbr of patients with lupus do not ana, i.e. Seronegative. ...Read more

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What does it mean if lupus test is negative?

Probably not lupus: Many people have symptoms suggestive of lupus but most turn out not to have the disease. The ANA and other blood tests are virtually always positive in patients with lupus. Negative tests mean you're not likely to have lupus. A bigger problem is false positive anas, in which case the teat is positive but the patient does not meed other diagnostic criteria to lupus. ...Read more

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Can you explain if it's possible to test negative for lupus but actually have it?

Very rarely: There is a big debate if there is sle without ana. A recent major reference on sle suggested that 98% of patients are ANA positive, leaving 2% without. However, the patients still need to have typical clinical manifestations to qualify for the diagnosis. ...Read more

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I have had a false positve syphills test since the age of 18 could i possibly have lupus?

Need further test: False positive RPR may suggest antibodies in the blood that is cross reacting with RPR test reagent. Common antibodies are antiphospholipid antibodies that gives false positive RPR. Lupus is diagnosed based on signs and symptoms PLUS presence of ANA antibodies in the blood. You can ask your MD to check for these antibodies by blood tests. ...Read more

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