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Doctor insights on: False Negative Herpes Blood Test

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What are odds of false negative for herpes blood test if sexually inactive for a year but have some common symptoms? Test was. 63.

What are odds of false negative for herpes blood test if sexually inactive for a year but have some common symptoms? Test was. 63.

1 to 4: 25% of people in this country have herpes, but 90% don't know it.
False negative tests from labs these days is rare.
If you have herpes simplex I (2/3 are oral) then this is a very common problem -- cold sores.
If you have hsv ii (2/3 are genital), then you may have more prolonged/painful lesions that require valtrex/acyclovir treatment. Herpes is forever. This blood test tells you your history. ...Read more

Herpes (Definition)

There are different types of herpes infections; herpes simplex infection of mouth (gingivostomatitis) and lips (labialis) are the most common. Others include genital herpes, and herpes zoster. Herpes infection could very mild to very dangerous depending on the type and location of the body affected. I ...Read more


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What is the likelihood of a false negative herpes type specific blood test with background of lupus (sle)?

What is the likelihood of a false negative herpes type specific blood test with background of lupus (sle)?

About 0% to 9%: Quest diagnostics' website states that their herpes type-specific IgG antibody test is 91-100% sensitive, so there are a few false negative results. A repeat test can be done 4-6 weeks later, if worried about a false negative. Lupus should not affect the result, but if a person is on strong immuno-suppressive therapy, his antibody production may be blocked, which may make test results unreliable. ...Read more

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What is the likelihood of false negative for g. Herpes using the herpeselect blood test if sexually inactive for over a year? Came back. 63. Thanks!

What is the likelihood of false negative for g. Herpes using the herpeselect blood test if sexually inactive for over a year? Came back. 63. Thanks!

Low but possible: The herpes select blood test is a reasonably reliable test that will indicate if an individual has had heroes 1 or 11 infection. It is not perfect and there is a small risk it is false negative. Even with a negative test, condoms are indicated to reduce transmission of stds. ...Read more

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Chances of having a false positive herpes type 1 blood test? 9.1 igg. While other STDs remain negative 0.0 igg. Had my test 2 weeks later after exposure.

Chances of having a false positive herpes type 1 blood test? 9.1 igg. While other STDs remain negative 0.0 igg. Had my test 2 weeks later after exposure.

True positive, but: As pointed out, many adults are positive for Herpes simplex type 1 by adolescence. New IgG antibodies usually ae being produced by day 10 after exposure, may not be detectable until 3 weeks, occasionally later. Particularly diseases such as syphilis and HIV may not be positive at 2 weeks. You should be retested at 4 weeks. HIV ...Read more

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If I had a negative herpes blood test at three weeks and seven weeks is it possible I still could have hsv-1?

If I had a negative herpes blood test at three weeks and seven weeks is it possible I still could have hsv-1?

Sure: If you just caught it after the last blood test, you would have herpes-1 now, but a negative last blood test. Herpes-1 is commonly found in people by the time they become adults. It is common enough that it is considered normal to have herpes-1 oral herpes. Usually, there is not a reason to repeated tests for herpes-1 unless a person is worried about catching it on his genitals via oral sex. ...Read more

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If 2 partners test negative for herpes by a blood test is it 100% true they do not have it?

If 2 partners test negative for herpes by a blood test is it 100% true they do not have it?

Not really: The labs aren't 100% sensitive or specific. But if neither partner has had symptoms, there's no reason to believe the couple is infected. Wondering why you ask. Best wishes. ...Read more

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Can people test negative of herpes by blood test if there isn't an outbreak at the moment?

Can people test negative of herpes by blood test if there isn't an outbreak at the moment?

No: Blood test is not dependent on the presence of an outbreak. If you were infected with herpes, the virus persists in the body, with or without outbreaks and the blood test is positive. ...Read more

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Is it possible for herpes culture and blood test to be wrong? I received negative for both...

Is it possible for herpes culture and blood test to be wrong? I received negative for both...

Not exactly: It is not so much the blood test is wrong, as it might be too early after infection to show up. Culture only positive if "catches" the organism to grow. There are a couple of types of herpes (hsv1/hsv2) as well. Usual to repeat blood work after 3-6 months if equivocal results. ...Read more

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Herpes blood test negative but still having itchy breakouts?

Herpes simplex: You need to see a doctor. Have no idea without seeing these outbreaks what they may be. ...Read more

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Can a herpes blood test be negative reading if indeed you do have the virus?

Can a herpes blood test be negative reading if indeed you do have the virus?

Depends: When a person initially contracts herpes, the blood test will be negative. After the body has mounted an immune response, which may take 6 to 8 weeks, the blood test will become positive and will always be positive. ...Read more

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I had 4 blood test for herpes and they came out negative should I take another one?

I had 4 blood test for herpes and they came out negative should I take another one?

Why?: The blood test for herpes simplex is not really useful in reflecting whether someone will have overt lesions or how often. ...Read more

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My friend got a blood test for herpes and it came back negative. She has never had any break outs. It is still possible that she could have herpes?

My friend got a blood test for herpes and it came back negative. She has never had any break outs. It is still possible that she could have herpes?

Not likely: With the exception of recent infection that has not resulted in a positive antibody response, a negative blood test and history of no breakouts, is reliable in excluding herpes. ...Read more

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Can you get a false positive herpes test if it's by swob? Should you get a blood test to know for a fact? And can folliculitis be mistaken for herpes?

Can you get a false positive herpes test if it's by swob? Should you get a blood test to know for a fact? And can folliculitis be mistaken for herpes?

False pos very rare: False positive tests for herpes simplex virus (HSV) (culture or PCR) are extremely rare and you probably don't need a blood test. However, a blood test still may be useful, e.g. to help tell new herpes from a recurrent outbreak, or if for some reason the virus type (HSV1 or 2) wasn't determined from the swab test. Folliculitis and herpes can be confused, but rarely by an experienced clinician. ...Read more

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I'm curious to know what are the chances of receiving a false positive on a blood test for herpes or any std?

I'm curious to know what are the chances of receiving a false positive on a blood test for herpes or any std?

Let me explain: No diagnostic test is perfect, but the test of std diseases are very good, rarely you get either false poivtive or flase negative.
It depends not only on the test but on the population it is used in. ...Read more

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Should a blood test for herpes be positive once I took the aciclovir, or it can be negative after aciclovir?

Should a blood test for herpes be positive once I took the aciclovir, or it can be negative after aciclovir?

IgG stays positive: The blood test we check for herpes infection is typically igg and igm tests. Igg remains positive for life, as long as there is an exposure, regardless of whether or not you've been treated. Igm is a measure of an acute (current) exposure, and will reduce if not currently active. ...Read more

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Is it possible to have a false positive on a herpes test? And do you know how long its suppose to take for the blood test results to come back?

False pos can occur: The standard blood tests for herpes simplex virus (HSV) are not perfect; false positive results can occur. The strength of the result -- i.e. the optical density ratio (also called ELISA ratio) -- is important in distinguishing true positive from false psotive results. Results usually are available in 2-5 days, but it varies a lot from one lab to another. ...Read more

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Do I infect other if I tested for herpes blood test IgG positive 158 and IgM negative 0.08? And what negative IgG means? Thank you

Do I infect other if I tested for herpes blood test IgG positive 158 and IgM negative 0.08? And what negative IgG means? Thank you

Immunoglobulins: Igg means you have been exposed. Igm means recent infection. Herpes is a difficult virus because you can spread it with out having symptoms. ...Read more

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I had herpes blood test 1&2 IgG positive 158 IgM negative 0.08 they told me I don't have herpes are they correct? I'm so confused please help me

Yes: They are correct. Igm tells us if you have an acute or active infection. This was negative, so you do not. The igg tells us you have previously been exposed or infected. This was positive, so you have. ...Read more

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Blood test results say herpes ab type 1 iGg: 0.10 and herpes type 2 igg: 0.23 if I'm negative why aren't the numbers 0 why are they 0.10 and 0.23?

Blood test results say herpes ab type 1 iGg: 0.10 and herpes type 2 igg: 0.23 if I'm negative why aren't the numbers 0 why are they 0.10 and 0.23?

Normal range: Our immune system is working all the time and making Igs (immunoglobulins) some of which cross react with many antigens including some Herpes molecules used in the test itself: that is the normal baseline or reference range ...Read more

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Is the herpeselect IGG blood test conclusive after 3 months of sexual encounter? Is a negative blood test reliable? Should another blood test be taken at 6 months post encounter to be extra sure? I tested negative for both types of herpes at 3 months.

If you were: Tested because of suspicious lesions you should have a follow up test. If your sexual partner is positive for HSV you are at risk of contracting the virus with each encounter. Many partners go years without becoming positve. Antiviral medication prophylaxis for the infected partner reduces the negative partners risk but not to zero. Condoms also reduce risk. Be healthy- your immune system is impt. ...Read more

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Docs swabbed for herpes but is the blood test more accurate? Can a swab come back negative when someone is indeed infected w/the virus?

Docs swabbed for herpes but is the blood test more accurate? Can a swab come back negative when someone is indeed infected w/the virus?

Not 100%: Neither the swab nor the serum antibody assays are altogether reliable. Both must be correlated with the clinical picture and any decision on treatment must take into consideration the known uncertainties. The same is true of most other life situations -- in a world full of uncertainty, love safely but love well. ...Read more

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If I had a positive IgG herpes blood test but never had Symptoms Why would the doctor tell me it is probably a false positive? Did he cross reference?

If I had a positive IgG herpes blood test but never had Symptoms Why would the doctor tell me it is probably a false positive? Did he cross reference?

It depends...: This depends on details you don't mention. If definitely positive (e.g., if you had a HerpeSelect IgG test and the HSV2 value is 3.5 or higher), it's not false positive: you are infected with HSV2. Lower numbers can be false positive, however. For HSV1, false positive are very rare; if positive, you're infected. ...Read more

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If I am tested for herpes, and the culture is positive and the blood test is negative. And my STD test is reactive for syphilis what should I believe?

If I am tested for herpes, and the culture is positive and the blood test is negative. And my STD test is reactive for syphilis what should I believe?

See your DR.: First infection with herpes or syphilis does not show pos blood test until about 2 weeks. Culture pos for herpes with neg blood test means you should be on full dose of valacyclovir or Acyclovir for at least a week. Repeat blood test for syphilis in about 1 month. ...Read more

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I get a tiny cut on my perineum semi often. Blood test for herpes negative. No itching, stings faintly if I keep touching it. No sex for a long time.?

I get a tiny cut on my perineum semi often. Blood test for herpes negative. No itching, stings faintly if I keep touching it. No sex for a long time.?

Perineum: Simple cut in the perineum possibly related to shaving but no obvious infection redness or drainage therefore no need for further workup or antibiotics unless it worsens over the next few weeks ...Read more