Doctor insights on:
Factor Xa Inhibitor Anti Coagulation Agent
Antibody to factor: Viii protein. People who are deficient in factor viii, i.e., have severe hemophilia, are treated with infusion of factor viii. Some make antibodies to factor viii and inhibit its function and are called factor viii inhibitors. Rarely non-hemophiliac can also develop such an inhibitor. ...Read more
Whether New oral anticoagulant drugs (pradaxa 150 2x/day) may be combined with anti-platelet drugs (Plavix (clopidogrel) 75 mg/day)?? i'm in Af also CAD??
Yes: be carful about bleeding because there is no antidote for these new agents. ...Read more
Azd 6244- mek inhibitor- a selective mitogen-activated protein kinase (mek) inhibitor. Mk 2206- akt inhibitor. Why prescription for me? It ? Nsclc/mets
Molecular targeting: These agents are designed to selectively knock out key pathways your tumor may use to grow. Presumably you already had your tumor tested for these different mutations. Ask the doctor offering these options to explain their rationale. These are investigational studies and many of the treatment costs may be covered-ask. ...Read more
Tendency to clot: Factor v leiden is a hereditary abnormality of a clotting protein that increases your risk of forming clots, notably in the veins (phlebitis). If you are undergoing a procedure that would also increase this risk (surgery, prolonged immobilization), Lovenox (enoxaparin) might be used preventively. It is only for short-term use, and oral drugs such as warfarin would be used if you need long-term protection. ...Read more
I'm in AF also CAD. Now taking pradaxa, may be change into plasmin (anti-coagulant drugs from china, Lumbrokinase)?
Pradaxa vs lumbrokin: I would NOT recommend this - while Pradaxa is costly - it comes with the approval of the FDA along with extensive testing for efficacy and safety. From my research Lumbrokinase is derived from earthworms and is still considered investigational. I would be leery of any medications obtained from off shore (NO I do NO work for big Pharma) their safety and efficacy are unproven. ...Read more
Relaxes vasc muscle: Angiotensin i is a hormone that is converted to angiotensin ii with the help of the angiotensin converting enzyme (ace). Angiotensin ii is a very powerful constrictor of vascular muscle and in doing so increases the pressure inside the vessels (the blood pressure). If you inhibit (or neutralize) the ace then you don't produce as much angiotensin ii and the BP does not increase. ...Read moreSee 1 more doctor answer
Which one better between pradaxa abd Plasmin Capsule( anti-coagulant drugs from china ; Lubrokinase)?
Not really: Aspirin at low doses has the ability to decrease the stickiness of your platelets and is often used to reduce chances of a stroke or heart attack. Aspirin does have anti-inflammatory properties, but its association with liver damage/failure and brain damage in kids (reye syndrome) led to rare use under the age of 16. ...Read moreSee 1 more doctor answer
Ultra High Tech!: These products(which are used to treat a wide variety of bleeding disorders like hemophilia, and von willebrand's disease) are made either by being completely free of human plasma derivative; or use a pasteurized form that is very safe. These products are not without there share of risks; and can potentially cause diseases as well. They are also very, very expensive so let the buyer beware! ...Read moreSee 1 more doctor answer
Are any of the new anticoags useful for factor v leiden and lupus anticoag. Antibody. On lovenox (enoxaparin) 100mg bid. Venous and arterial clotting and pes. ?
Maybe: The newer medications to prevent blood clots are not approved for use in the us for your condition. There is published research in europe showing that these medications can be used effectively for your type of problem. My personal bias is that you should wait until more research has been done. Your doctor can help advise you as to the status of this research as it evolves. ...Read more
Xarelto: Yes. Xarelto (rivaroxaban) is equally effective as coumadin( warfarin). Initially it was given only for irregular heart beat atrial fibrillation. Now the use is expanded to leg clot DVT and lung clot pe. The advantage of xarelto over Coumadin is that there is no periodic blood checkup for pt/ inr just like coumadin. It can be expensive & inconvenient. Can't monitor level & no antidote. ...Read more
I'm wondering why are anticoagulants lesser effective than anti-platelet aggregation drugs in arteries?
For recurrent stroke prevention, which is best: ASA vs Plavix (clopidogrel) vs ASA/Plavix (clopidogrel) vs Aggrenox? Risk of bleeding worse with any particular?
Pretty good, but...: They are essentially equivalent in thinning the blood to replace coumadin (warfarin), (warfarin) but they require twice daily dosing. Yes, you don't have to get your blood tested like you do with coumadin (warfarin), (warfarin) but if you have a bad bleed, there is no antidote for either you mentioned, like there is for coumadin (warfarin). So one must weigh the risks vs. The benefits, as we do everyday in medicine. ...Read moreSee 1 more doctor answer
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