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Doctor insights on: Factor Viii Deficiency

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Dr. Jan Lei Iwata
26 doctors shared insights

Factor Viii Deficiency (Overview)

Factor VIII deficiency (also known as Hemophilia A) is disease of the blood in which a person lacks a protein necessary for clotting. These patients are prone to excessive bleeding from minor trauma.


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What sort of disorder is factor viii deficiency?

R/o vWD: A patient with von willebrand's disease, which is extremely common and usually mild, may be told they have factor viii deficiency. ...Read more

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Dr. Jan Lei Iwata
26 doctors shared insights

Factor Viii Deficiency (Overview)

Factor VIII deficiency (also known as Hemophilia A) is disease of the blood in which a person lacks a protein necessary for clotting. These patients are prone to excessive bleeding from minor trauma.


2

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What are the symptoms of factor viii deficiency?

What are the symptoms of factor viii deficiency?

Bleeding/bruising: Factor viii deficiency or hemophilia- is a bleeding disorder. It is hereditary in most cases . The symptoms would be spontaneous bleeding- either in the joints, skin/gum, or other places etc or prolonged bleeding. The severity of bleeding will depend on how low the level of the factor viii is.. Usually the bleeding episodes will manifest at early age. Discuss further with your hematologist. ...Read more

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What are the tests for factor viii deficiency?

What are the tests for factor viii deficiency?

Blood tests and: Family history. Blood tests for levels of factor viii are available, though simpler tests, e.g., PTT with appropriate family history may be sufficient. ...Read more

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Can you tell me if someone is heterozygous w/ the hemophilia gene, is it possible for them to still have factor viii deficiency?

Can you tell me if someone is heterozygous w/ the hemophilia gene, is it possible for them to still have factor viii deficiency?

Yes, in men: Hemophilia is a sex linked disorder and men develop the disease when there only x chromosome has the defective gene. See this site for more info. http://www.nlm.nih.gov/medlineplus/ency/article/000538.htm. ...Read more

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What is the treatment for factor viii deficiency?

What is the treatment for factor viii deficiency?

Factor VIII: Concentrate. Factor viii is prepared by recombinant technology, though it may also be extracted from human plasma. Depending on the severity of deficiency, factor viii may be given prophylactically or to treat episodes of bleeding. The drug is given intravenously. ...Read more

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What are the tests for factor viii deficiency?

Blood tests and: Family history. Blood tests for levels of factor viii are available, though simpler tests, e.g., PTT with appropriate family history may be sufficient. ...Read more

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What sort of disorder is factor viii deficiency?

R/o vWD: A patient with von willebrand's disease, which is extremely common and usually mild, may be told they have factor viii deficiency. ...Read more

See 2 more doctor answers
9

9
What are the symptoms of factor viii deficiency?

Bleeding/bruising: Factor viii deficiency or hemophilia- is a bleeding disorder. It is hereditary in most cases . The symptoms would be spontaneous bleeding- either in the joints, skin/gum, or other places etc or prolonged bleeding. The severity of bleeding will depend on how low the level of the factor viii is.. Usually the bleeding episodes will manifest at early age. Discuss further with your hematologist. ...Read more

See 1 more doctor answer
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Can you tell me if someone is heterozygous w/ the hemophilia gene, is it possible for them to still have factor viii deficiency?

Yes, in men: Hemophilia is a sex linked disorder and men develop the disease when there only x chromosome has the defective gene. See this site for more info. http://www.nlm.nih.gov/medlineplus/ency/article/000538.htm. ...Read more

See 1 more doctor answer
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What is the treatment for factor viii deficiency?

Factor VIII: Concentrate. Factor viii is prepared by recombinant technology, though it may also be extracted from human plasma. Depending on the severity of deficiency, factor viii may be given prophylactically or to treat episodes of bleeding. The drug is given intravenously. ...Read more

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What to do along with Factor VIII for severe hemarthrosis along with large joint effusion of knee in patient with Hemophilia A?

What to do along with Factor VIII for severe hemarthrosis along with large joint effusion of knee in patient with Hemophilia A?

Xfusion with factor-: -Vlll, then aspiration of the joint. Chronic hemarthrosis destroys the articular cartilages. It consumes O2, & does not allow it 2 B nourished. Cartilages only O2 comes from the joint fluid, but it's not available since the inflammatory reaction 2 the blood consumes it ...Read more

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Are a mildly elevated PTT and mildly elevated Coagulation Factor VIII Activity, as all as a high ALDO/PRA RATIO something to be concerned about and is there a correlation?

Are a mildly elevated PTT and mildly elevated Coagulation Factor VIII Activity, as all as a high ALDO/PRA RATIO something to be concerned about and is there a correlation?

PTT and ARR: Are a mildly elevated PTT and mildly elevated Coagulation Factor VIII Activity, as all as a high ALDO/PRA RATIO something to be concerned about and is there a correlation? ANS: no and No. I specialize in ARR problems. Happy to do 2nd opinion. ...Read more

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What are the functions of factor viii? What if you're low on your factor viii?

Blood clotting: Factor viii is a clotting factor. This is one of many that help you stop bleeding from a cut. If you are low on factor 8, then you will bleed longer than someone who has normal factor 8. The associated condition is called hemophilia a. Treatment is done by replacing the factor 8 when necessary, such as after a trauma or surgery. In severe cases, you may be given factor 8 regularly for prevention. ...Read more

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Factor viii inhibitor in hemophilia? What is a factor viii inhibitor?

Antibody to factor: Viii protein. People who are deficient in factor viii, i.e., have severe hemophilia, are treated with infusion of factor viii. Some make antibodies to factor viii and inhibit its function and are called factor viii inhibitors. Rarely non-hemophiliac can also develop such an inhibitor. ...Read more

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Why plasmapheresis is used to remove factor viii; could this be useful in a procoagulable state?

Why plasmapheresis is used to remove factor viii; could this be useful in a procoagulable state?

No.: Plasmapheresis removes all the clotting proteins, including factor viii, but the body rapidly replaces what is taken out. Usually all proteins are back to their usual levels within 24 hours. This would not be long enough to provide meaningful anti-coagulation. ...Read more