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Doctor insights on: Factor Viii

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Factor viii inhibitor in hemophilia? What is a factor viii inhibitor?

Factor viii inhibitor in hemophilia? What is a factor viii inhibitor?

Antibody to factor: Viii protein. People who are deficient in factor viii, i.e., have severe hemophilia, are treated with infusion of factor viii. Some make antibodies to factor viii and inhibit its function and are called factor viii inhibitors. Rarely non-hemophiliac can also develop such an inhibitor. ...Read more

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What are the functions of factor viii? What if you're low on your factor viii?

What are the functions of factor viii?  What if you're low on your factor viii?

Blood clotting: Factor viii is a clotting factor. This is one of many that help you stop bleeding from a cut. If you are low on factor 8, then you will bleed longer than someone who has normal factor 8. The associated condition is called hemophilia a. Treatment is done by replacing the factor 8 when necessary, such as after a trauma or surgery. In severe cases, you may be given factor 8 regularly for prevention. ...Read more

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Why plasmapheresis is used to remove factor viii; could this be useful in a procoagulable state?

Why plasmapheresis is used to remove factor viii; could this be useful in a procoagulable state?

No.: Plasmapheresis removes all the clotting proteins, including factor viii, but the body rapidly replaces what is taken out. Usually all proteins are back to their usual levels within 24 hours. This would not be long enough to provide meaningful anti-coagulation. ...Read more

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What are the functions of factor viii? What if you're low on your factor viii?

Blood clotting: Factor viii is a clotting factor. This is one of many that help you stop bleeding from a cut. If you are low on factor 8, then you will bleed longer than someone who has normal factor 8. The associated condition is called hemophilia a. Treatment is done by replacing the factor 8 when necessary, such as after a trauma or surgery. In severe cases, you may be given factor 8 regularly for prevention. ...Read more

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What test can be done for someone with thrombophilia factor viii?

What test can be done for someone with thrombophilia factor viii?

Get exact diagnosis: Hemophilia with factor viii deficiency is the most common kind. These people today for the most part live near-normal lives thanks to biotechnology. There is talk of a thrombophilia (excess blood clotting / deep vein thrimbi) due to elevated levels of factor viii; this is a subspecialty hematologist question. ...Read more

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Factor viii inhibitor in hemophilia? What is a factor viii inhibitor?

Antibody to factor: Viii protein. People who are deficient in factor viii, i.e., have severe hemophilia, are treated with infusion of factor viii. Some make antibodies to factor viii and inhibit its function and are called factor viii inhibitors. Rarely non-hemophiliac can also develop such an inhibitor. ...Read more

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Why plasmapheresis is used to remove factor viii; could this be useful in a procoagulable state?

No.: Plasmapheresis removes all the clotting proteins, including factor viii, but the body rapidly replaces what is taken out. Usually all proteins are back to their usual levels within 24 hours. This would not be long enough to provide meaningful anti-coagulation. ...Read more

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What sort of disorder is factor viii deficiency?

R/o vWD: A patient with von willebrand's disease, which is extremely common and usually mild, may be told they have factor viii deficiency. ...Read more

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What are the symptoms of factor viii deficiency?

What are the symptoms of factor viii deficiency?

Bleeding/bruising: Factor viii deficiency or hemophilia- is a bleeding disorder. It is hereditary in most cases . The symptoms would be spontaneous bleeding- either in the joints, skin/gum, or other places etc or prolonged bleeding. The severity of bleeding will depend on how low the level of the factor viii is.. Usually the bleeding episodes will manifest at early age. Discuss further with your hematologist. ...Read more

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