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Doctor insights on: Factor Vii Activity

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Factor viii inhibitor in hemophilia? What is a factor viii inhibitor?

Factor viii inhibitor in hemophilia? What is a factor viii inhibitor?

Antibody to factor: Viii protein. People who are deficient in factor viii, i.e., have severe hemophilia, are treated with infusion of factor viii. Some make antibodies to factor viii and inhibit its function and are called factor viii inhibitors. Rarely non-hemophiliac can also develop such an inhibitor. ...Read more

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20y o woman, have thrombophilia factor vii (7) heterozygote gene mutation, I have had 7week miscarriage, is thromb. the cause? I am very healthy

20y o woman, have thrombophilia factor vii (7) heterozygote gene mutation, I have had 7week miscarriage, is thromb. the cause? I am very healthy

Yes : Patients with these problems tend to have recurrent miscarriages which can bee prevented by Aspirin or anticoagulant ,Heprin therapy.You need to be followed by a high risk doctor for future.Goodluck ...Read more

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Is leiden factor v genetic?

Is leiden factor v genetic?

Yes: Factor v leiden is a genetic condition. If you have one copy of a fvl mutation, you are heterozygous with an increased risk of blood clotting. If you have 2 copies you are homozygous with an even higher risk of clotting. The inheritence pattern is simple mendelian genetics. You get one copy of the gene from your mother and one from your father. ...Read more

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What does a low von willebrand factor (vwf) ag: 33 %, low vwf activity: 29 % and factor viii activity: 52 % result mean?

What does a  low von willebrand factor (vwf) ag: 33 %, low vwf activity: 29 % and factor viii activity: 52 % result mean?

VWD: First of all, these test need to be repeated at least one more time, prederably while you are off all medications. If persistently low, this may mean that you have von willibrand disease (VWD) which is a bleeding disorder. These are several types of VWD and more testing is needed to determine the type. You need to see a hematologist for this. Avoid any surgery and trauma. ...Read more

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What is the disease factor v leiden?

What is the disease factor v leiden?

Blood clots: People with leiden variant of clotting factor v have tendency to form clots in blood vessels and develop thromboses in veins that cause pulmonary emboli. Women on birth control pills are more susceptible to clot formation if they have factor v leiden. ...Read more

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What genes play an important role in stroke?

What genes play an important role in stroke?

Many: There is no "stroke gene". There are many conditions which are genetically determined, such leiden factor v deficiency which leads to stroke. If you have strong family history of stroke, you should find out what condition(s) your family has contributing to their strokes. This is a more productive approach than searching the human genome. ...Read more

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How severe is factor v leiden (homozygous)?

How severe is factor v leiden (homozygous)?

Risk for blood clots: People homozygous for factor v leiden are about 50 times more at risk of developing blood clots in their veins and complications related to that. See this site for more info. http://www.mayoclinic.org/diseases-conditions/factor-v-leiden/basics/definition/con-20032637. ...Read more

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What is leiden factor v?

What is leiden factor v?

Clotting abnormality: Factor v leiden is a genetic mutation in one of the blood's clotting proteins. People with this mutation are at higher risk of forming blood clots. ...Read more

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Is your risk for arthritis genetic or activity related?

Is your risk for arthritis genetic or activity related?

Both: The cause of autoimmune type arthritis such as rheumatoid arthritis is unknown but may occur when certain factors in the environment trigger the activation of the immune system to inappropriately attack the body's own tissues. There may be some genetic predisposition. Repetitive trauma, instability of joints, and fractures can lead to "wear and tear" osteoarthritis or post-traumatic arthritis. ...Read more

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What sort of disorder is factor viii deficiency?

R/o vWD: A patient with von willebrand's disease, which is extremely common and usually mild, may be told they have factor viii deficiency. ...Read more

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What genes play an important role in cerebrovascular disease?

What genes play an important role in cerebrovascular disease?

Many: Since there are many types of stroke, this is a very complicated question. Most strokes are related to atherosclerosis ( fat deposit in the arteries). So the genes involved ( there are many) in lipid (fat) metabolism and blood pressure regulation are important. One important set of genes seems to be located on chromosome number 9. In any case this is an active area of medical research. ...Read more

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What is factor v leiden syndrome?

What is factor v leiden syndrome?

Thrombosis: People who inherit the leiden variant of coagulation factor v are at incresed risk of venous thrombosis. Those who are heterozygotes their risk is 5-10 fold higher, homozygotes are about 50 fold greater risk. Women on birth contol pills are partiuclarly susceptible to thrombosis if they have leiden factor v. If the affected individual develops thromobsis, life long anti-coagulation may be needed. ...Read more

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What does Acquired Coagulation Factor Deficiency mean relating to surgery?

What does Acquired Coagulation Factor Deficiency mean relating to surgery?

Higher risk of bleed: ... is a concern. A select factor deficiency (missing, depleted or inhibited for various reasons) can adversely impact at least 1 of 3 pathways that prevent bleeding. Some factor deficiencies are more serious than others. The surgeon usually consults a hematologist in these cases so that there are no problems during or around the surgery. No excess bleeding w/ any prior surgery = good omen. ...Read more

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What genes play an important role in angina?

What genes play an important role in angina?

Unknown : This information is not yet known. Stay tuned (and check back in 10 years). ...Read more

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Do environmental factors play a role in the progression of beta-thalassemia?

Do environmental factors play a role in the progression of beta-thalassemia?

No, but. . .: Environmental factors generally do not play a role in beta thalassemia. However, a patient can be worsened by conditions that typically worsen anemia, such as dietary iron deficiency, other nutrient deficiencies (such as folate (folic acid) or vitamin b12), lead poisoning, or infections with viruses that can cause anemia (such as parvovirus b19). Vacationing at high altitudes may cause symptoms of low oxygen. ...Read more

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