Doctor insights on:
Factor Vii Activity
Antibody to factor: Viii protein. People who are deficient in factor viii, i.e., have severe hemophilia, are treated with infusion of factor viii. Some make antibodies to factor viii and inhibit its function and are called factor viii inhibitors. Rarely non-hemophiliac can also develop such an inhibitor. ...Read more
20y o woman, have thrombophilia factor vii (7) heterozygote gene mutation, I have had 7week miscarriage, is thromb. the cause? I am very healthy
Yes: Factor v leiden is a genetic condition. If you have one copy of a fvl mutation, you are heterozygous with an increased risk of blood clotting. If you have 2 copies you are homozygous with an even higher risk of clotting. The inheritence pattern is simple mendelian genetics. You get one copy of the gene from your mother and one from your father. ...Read moreSee 1 more doctor answer
What does a low von willebrand factor (vwf) ag: 33 %, low vwf activity: 29 % and factor viii activity: 52 % result mean?
VWD: First of all, these test need to be repeated at least one more time, prederably while you are off all medications. If persistently low, this may mean that you have von willibrand disease (VWD) which is a bleeding disorder. These are several types of VWD and more testing is needed to determine the type. You need to see a hematologist for this. Avoid any surgery and trauma. ...Read more
Which factor plays a greater role in affecting life expectancy , diet, exercise, lifestyle, genes?
Hard to say: Probably genetics.Get a more detailed answer ›
Many: There is no "stroke gene". There are many conditions which are genetically determined, such leiden factor v deficiency which leads to stroke. If you have strong family history of stroke, you should find out what condition(s) your family has contributing to their strokes. This is a more productive approach than searching the human genome. ...Read moreSee 1 more doctor answer
Risk for blood clots: People homozygous for factor v leiden are about 50 times more at risk of developing blood clots in their veins and complications related to that. See this site for more info. http://www.mayoclinic.org/diseases-conditions/factor-v-leiden/basics/definition/con-20032637. ...Read more
Is a simple coagulation lab test (PT/PTT INR & Fibrinogen) sufficient to diagnose Protein C,
&/or Factor V leidmen mutation disorders?
Both: The cause of autoimmune type arthritis such as rheumatoid arthritis is unknown but may occur when certain factors in the environment trigger the activation of the immune system to inappropriately attack the body's own tissues. There may be some genetic predisposition. Repetitive trauma, instability of joints, and fractures can lead to "wear and tear" osteoarthritis or post-traumatic arthritis. ...Read moreSee 1 more doctor answer
Many: Since there are many types of stroke, this is a very complicated question. Most strokes are related to atherosclerosis ( fat deposit in the arteries). So the genes involved ( there are many) in lipid (fat) metabolism and blood pressure regulation are important. One important set of genes seems to be located on chromosome number 9. In any case this is an active area of medical research. ...Read moreSee 1 more doctor answer
Thrombosis: People who inherit the leiden variant of coagulation factor v are at incresed risk of venous thrombosis. Those who are heterozygotes their risk is 5-10 fold higher, homozygotes are about 50 fold greater risk. Women on birth contol pills are partiuclarly susceptible to thrombosis if they have leiden factor v. If the affected individual develops thromobsis, life long anti-coagulation may be needed. ...Read more
Higher risk of bleed: ... is a concern. A select factor deficiency (missing, depleted or inhibited for various reasons) can adversely impact at least 1 of 3 pathways that prevent bleeding. Some factor deficiencies are more serious than others. The surgeon usually consults a hematologist in these cases so that there are no problems during or around the surgery. No excess bleeding w/ any prior surgery = good omen. ...Read moreSee 1 more doctor answer
No, but. . .: Environmental factors generally do not play a role in beta thalassemia. However, a patient can be worsened by conditions that typically worsen anemia, such as dietary iron deficiency, other nutrient deficiencies (such as folate (folic acid) or vitamin b12), lead poisoning, or infections with viruses that can cause anemia (such as parvovirus b19). Vacationing at high altitudes may cause symptoms of low oxygen. ...Read moreSee 1 more doctor answer