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Doctor insights on: Factor V Leiden Test

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Is leiden factor v genetic?

Is leiden factor v genetic?

Yes: Factor v leiden is a genetic condition. If you have one copy of a fvl mutation, you are heterozygous with an increased risk of blood clotting. If you have 2 copies you are homozygous with an even higher risk of clotting. The inheritence pattern is simple mendelian genetics. You get one copy of the gene from your mother and one from your father. ...Read more

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How severe is factor v leiden (homozygous)?

How severe is factor v leiden (homozygous)?

Risk for blood clots: People homozygous for factor v leiden are about 50 times more at risk of developing blood clots in their veins and complications related to that. See this site for more info. http://www.mayoclinic.org/diseases-conditions/factor-v-leiden/basics/definition/con-20032637. ...Read more

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What is factor v leiden syndrome?

What is factor v leiden syndrome?

Thrombosis: People who inherit the leiden variant of coagulation factor v are at incresed risk of venous thrombosis. Those who are heterozygotes their risk is 5-10 fold higher, homozygotes are about 50 fold greater risk. Women on birth contol pills are partiuclarly susceptible to thrombosis if they have leiden factor v. If the affected individual develops thromobsis, life long anti-coagulation may be needed. ...Read more

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Is there a link between hemangiomas and factor v leiden mutations?

Is there a link between hemangiomas and factor v leiden mutations?

No: Both are very common and this is probably a coincidence. The factor v gene isn't part of the pathway by which new vessels form, and this speaks against there being any correlation. There are a few other genetic syndromes with distinctive hemangiomas, but factor v has not been linked to any. ...Read more

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I found out I have Factor V Deficiency. My mother has Factor V leiden. What is the difference between those?

I found out I have Factor V Deficiency. My mother has Factor V leiden. What is the difference between those?

Huge difference: Factor V deficiency of a clotting factor which can result in a hemophilia like illness with excessive bleeding. On the other hand Factor V Leiden refers to a mutation which increases the risk of clotting and thrombosis. The distinction is very important. Women with Factor V Leiden should not take hormonal contraception. Please clarify your diagnosis with your physician as soon as possible! ...Read more

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Does APTT test result indicate if i have excessive clotting disorder such as factor v lieden? my result is 30. Seconds thanks

Does APTT test result indicate if i have excessive clotting disorder such as factor v lieden? my result is 30. Seconds

thanks

No: this is a common misconception. APTT is basically useless in detecting hypercagulable blood. Specific assays or gene tests are required. ...Read more

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Is factor 7 gene mutation (heterozygote) thrombophila?

No: Factor 7 mutation is very rare and causes increased risk of bleeding (not being able to clot). Factor 5 deficiency is the most common form of thrombophilia (increased risk of abnormal clotting). ...Read more

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What does a low von willebrand factor (vwf) ag: 33 %, low vwf activity: 29 % and factor viii activity: 52 % result mean?

What does a  low von willebrand factor (vwf) ag: 33 %, low vwf activity: 29 % and factor viii activity: 52 % result mean?

VWD: First of all, these test need to be repeated at least one more time, prederably while you are off all medications. If persistently low, this may mean that you have von willibrand disease (VWD) which is a bleeding disorder. These are several types of VWD and more testing is needed to determine the type. You need to see a hematologist for this. Avoid any surgery and trauma. ...Read more

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20y o woman, have thrombophilia factor vii (7) heterozygote gene mutation, I have had 7week miscarriage, is thromb. the cause? I am very healthy

20y o woman, have thrombophilia factor vii (7) heterozygote gene mutation, I have had 7week miscarriage, is thromb. the cause? I am very healthy

Yes : Patients with these problems tend to have recurrent miscarriages which can bee prevented by Aspirin or anticoagulant ,Heprin therapy.You need to be followed by a high risk doctor for future.Goodluck ...Read more

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Factor viii inhibitor in hemophilia? What is a factor viii inhibitor?

Factor viii inhibitor in hemophilia? What is a factor viii inhibitor?

Antibody to factor: Viii protein. People who are deficient in factor viii, i.e., have severe hemophilia, are treated with infusion of factor viii. Some make antibodies to factor viii and inhibit its function and are called factor viii inhibitors. Rarely non-hemophiliac can also develop such an inhibitor. ...Read more

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Are any of the new anticoags useful for factor v leiden and lupus anticoag. Antibody. On lovenox (enoxaparin) 100mg bid. Venous and arterial clotting and pes. ?

Are  any of the new anticoags useful for factor v leiden and lupus anticoag. Antibody. On lovenox (enoxaparin) 100mg bid. Venous and arterial clotting and pes. ?

Maybe: The newer medications to prevent blood clots are not approved for use in the us for your condition. There is published research in europe showing that these medications can be used effectively for your type of problem. My personal bias is that you should wait until more research has been done. Your doctor can help advise you as to the status of this research as it evolves. ...Read more

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Av test positive .Ra factor positive .Joint pain .Ccp antibody test negative.Raised esr.Plz diagnose my disease.

Av test positive .Ra factor positive .Joint pain .Ccp antibody test negative.Raised esr.Plz diagnose my disease.

Cannot diagnose: Although these lab values are interesting, taken out of the context of your symptoms and findings on physical examination, plus further testing there is no way in which to diagnose over the internet. See a rheumatologist and get appropriately assessed. ...Read more

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Hemotologist confirmed Enoxaparin causing me to have elevated liver enzymes. 6w pregnant- history of PEs, Factor V, Factor II. Any other options?

Hemotologist confirmed Enoxaparin causing me to have elevated liver enzymes.  6w pregnant- history of PEs, Factor V, Factor II.  Any other options?

Anticoagulant: Being pregnant, your option unfortunately, is somewhat limited to unfractionated subcutaneous heparin injections, most likely three times a day or as recommended by your hematologist. ...Read more

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What is factor five leiden lovenox (enoxaparin) used to treat?

What is factor five leiden lovenox (enoxaparin) used to treat?

Tendency to clot: Factor v leiden is a hereditary abnormality of a clotting protein that increases your risk of forming clots, notably in the veins (phlebitis). If you are undergoing a procedure that would also increase this risk (surgery, prolonged immobilization), Lovenox (enoxaparin) might be used preventively. It is only for short-term use, and oral drugs such as warfarin would be used if you need long-term protection. ...Read more

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I'm 23 male my ra factor is 100 positive my ccp is 16 negative , sed rate 12 negative, and crp .13 negative can high blood fats cause + ra factor?

I'm 23 male my ra factor is 100 positive my ccp is 16 negative , sed rate 12 negative, and crp .13 negative can high blood fats cause + ra factor?

See below: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, rheumatoid factor is not a specific marker for rheumatoid arthritis. It can be positive in many situations, including recovery from infection. High blood fat per se is not a cause of +RA factor. ...Read more

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Lupus sle panel blood test shows pos myocardial ab, if, myocardial ab titer 1:40, gastric pareital cell 43, RA factor 30. What does this mean?

Lupus sle panel blood test shows pos myocardial ab, if, myocardial ab titer 1:40, gastric pareital cell 43, RA factor 30. What does this mean?

Difficult to say: Without specific patient scenario, it is difficult to interpret. You can have lab test anomaly without clinical disease. Open the case... ...Read more

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Av test positive .Ra factor positive .Joint pain.Esr raised.Crp positive. Plz diagnose my disease.

Rheumatoid arthritis: Have a ccp antibody test done. If it is positive, you have rheumatoid arthritis. I urge you to see a rheumatologist for this issue. ...Read more

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