Doctor insights on:
Factor V Leiden Test
Yes: Factor v leiden is a genetic condition. If you have one copy of a fvl mutation, you are heterozygous with an increased risk of blood clotting. If you have 2 copies you are homozygous with an even higher risk of clotting. The inheritence pattern is simple mendelian genetics. You get one copy of the gene from your mother and one from your father. ...Read moreSee 1 more doctor answer
Risk for blood clots: People homozygous for factor v leiden are about 50 times more at risk of developing blood clots in their veins and complications related to that. See this site for more info. http://www.mayoclinic.org/diseases-conditions/factor-v-leiden/basics/definition/con-20032637. ...Read more
Thrombosis: People who inherit the leiden variant of coagulation factor v are at incresed risk of venous thrombosis. Those who are heterozygotes their risk is 5-10 fold higher, homozygotes are about 50 fold greater risk. Women on birth contol pills are partiuclarly susceptible to thrombosis if they have leiden factor v. If the affected individual develops thromobsis, life long anti-coagulation may be needed. ...Read more
Is a simple coagulation lab test (PT/PTT INR & Fibrinogen) sufficient to diagnose Protein C,
&/or Factor V leidmen mutation disorders?
No: Both are very common and this is probably a coincidence. The factor v gene isn't part of the pathway by which new vessels form, and this speaks against there being any correlation. There are a few other genetic syndromes with distinctive hemangiomas, but factor v has not been linked to any. ...Read more
I found out I have Factor V Deficiency. My mother has Factor V leiden. What is the difference between those?
Huge difference: Factor V deficiency of a clotting factor which can result in a hemophilia like illness with excessive bleeding. On the other hand Factor V Leiden refers to a mutation which increases the risk of clotting and thrombosis. The distinction is very important. Women with Factor V Leiden should not take hormonal contraception. Please clarify your diagnosis with your physician as soon as possible! ...Read more
Does APTT test result indicate if i have excessive clotting disorder such as factor v lieden? my result is 30. Seconds
What does a low von willebrand factor (vwf) ag: 33 %, low vwf activity: 29 % and factor viii activity: 52 % result mean?
VWD: First of all, these test need to be repeated at least one more time, prederably while you are off all medications. If persistently low, this may mean that you have von willibrand disease (VWD) which is a bleeding disorder. These are several types of VWD and more testing is needed to determine the type. You need to see a hematologist for this. Avoid any surgery and trauma. ...Read more
20y o woman, have thrombophilia factor vii (7) heterozygote gene mutation, I have had 7week miscarriage, is thromb. the cause? I am very healthy
Antibody to factor: Viii protein. People who are deficient in factor viii, i.e., have severe hemophilia, are treated with infusion of factor viii. Some make antibodies to factor viii and inhibit its function and are called factor viii inhibitors. Rarely non-hemophiliac can also develop such an inhibitor. ...Read more
Are any of the new anticoags useful for factor v leiden and lupus anticoag. Antibody. On lovenox (enoxaparin) 100mg bid. Venous and arterial clotting and pes. ?
Maybe: The newer medications to prevent blood clots are not approved for use in the us for your condition. There is published research in europe showing that these medications can be used effectively for your type of problem. My personal bias is that you should wait until more research has been done. Your doctor can help advise you as to the status of this research as it evolves. ...Read more
Av test positive .Ra factor positive .Joint pain .Ccp antibody test negative.Raised esr.Plz diagnose my disease.
Cannot diagnose: Although these lab values are interesting, taken out of the context of your symptoms and findings on physical examination, plus further testing there is no way in which to diagnose over the internet. See a rheumatologist and get appropriately assessed. ...Read more
Hemotologist confirmed Enoxaparin causing me to have elevated liver enzymes. 6w pregnant- history of PEs, Factor V, Factor II. Any other options?
Tendency to clot: Factor v leiden is a hereditary abnormality of a clotting protein that increases your risk of forming clots, notably in the veins (phlebitis). If you are undergoing a procedure that would also increase this risk (surgery, prolonged immobilization), Lovenox (enoxaparin) might be used preventively. It is only for short-term use, and oral drugs such as warfarin would be used if you need long-term protection. ...Read more
Hbg, hct, rbc, plt, mvc, all at top of normal range. Does this ^ clotting risk? Hx: fact v leiden & aps. On lovenox (enoxaparin) 100mg bid
No: These values would not increase the risk. Normal is normal. ...Read more
I'm 23 male my ra factor is 100 positive my ccp is 16 negative , sed rate 12 negative, and crp .13 negative can high blood fats cause + ra factor?
See below: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, rheumatoid factor is not a specific marker for rheumatoid arthritis. It can be positive in many situations, including recovery from infection. High blood fat per se is not a cause of +RA factor. ...Read more
Lupus sle panel blood test shows pos myocardial ab, if, myocardial ab titer 1:40, gastric pareital cell 43, RA factor 30. What does this mean?
Difficult to say: Without specific patient scenario, it is difficult to interpret. You can have lab test anomaly without clinical disease. Open the case... ...Read more
Av test positive .Ra factor positive .Joint pain.Esr raised.Crp positive. Plz diagnose my disease.
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