Doctor insights on:
Extragastrointestinal Stromal Tumor
Are carcinoid tumors carcinoma? Is malignant metastatic stomach carcinoma that's hereditary a carcinoid cancer? carcinoid Neuroendocrine tumors?
"tumor" literally translates as "mass", so even a fresh bruise could be called a "tumor". Doctors use the term "neoplasm" (tranlates literally as new growth) to describe tumors that are abnormal growths of cells. These may be benign or malignant; "malignant" = cancer. In everyday usage, we use "tumor" ...Read more
Colon biopsy:huge tubulovillous adenoma with marked atypia, multi foci adenocarcinoma in situ &one tiny focus suggestive of micro invasion.Is it cancer?
Unfortunate: This is usually an unfortunate situation. The most common primary site will be somewhere in the intestinal tract, like the stomach. The pathologists will try many stains on the tissue to help define the origin. This helps with choosing the most appropriate chemotherapy. ...Read moreSee 1 more doctor answer
Subtype of colon Ca: Mucin producing metastatic adenoca of the colon is derived from a primary adenoCa of colon producing large amounts of extracelluar mucin with greater than a 50% mucinous component.. The proximal colon and appendix represents 10-20% of these colorectal neoplasms . The rt. colon is the usual source for most of these lesions presenting with more advanced forms of disease than other colonic sites. ...Read more
Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?
Yes, for both: Hepatocellular Carcinoma is commonly treated with Sorafenib which is a type of targeted therapy. This is a good choice of treatment in case you have not yet received this drug. Immunotherapy using PD-1 inhibitors has also shown some modest evidence of benefit although it is not yet FDA approved for this indication. Ask your oncologist to guide your treatment further. ...Read more
Tuberous sclerosis have a large percentage of which of the following tumors? 1-renal cell carcenoma 2-adenoma 3-angiomyolipoma 3-oncocytoma 4-sarcoma
What does each word/phrase mean?Infiltrating, well differentiated adenocarcinoma; carcinoma focally invades superficial submucosa;no lymphovascular invasion?Is surgery advised for this type of report?
For colon cancer,Peritoneal Carcinoma's, roughly what percentage of those malignant tumors are cancerous.I read malignant tumors are 100% cancer.
Urothelial carcinoma of the bladder with transmural and direct prostatic stromal invasion: does extent of stromal invasion significantly impact patient outcome?
Yes and No: Survival by stage which correlates with invasiveness shows survival drop as stage increases. However, the staging system is going to calll 1mm into the prostate a t4a and 25mm into the prostate as the same. So, it is hard to tell that the exactly invasion depth into the prostate is proven to correlate with outcome. In general...The more aggressive it is, the worse patients do. ...Read more
Colon surgery:tumor size=2cm.Pathologic staging(pt3, n1b, mx).2/17 lymph nodes show metastatic.Margins of resection free of carcinoma.Need chemotherapy?
Yes: Chemotherapy regimens based on the drug Fluorouracil (5-fu) have been part of the treatment for high-risk stage ii or stage iii colon cancer. Many clinical trials have shown that these regimens improve overall survival primarily by reducing the high risk of recurrence within the first two years after surgery. ...Read more
Mesothelioma biopsy says 'portions of fibrous tissue infiltrated by malignant cells forming nests. tumor cells +'ve for CK7 and calretinin. prognosis?
Marker not prognosis: CK7 and calretinin are used to verify that the tumor is mesothelial in origin (versus adenocarcinoma of the lung). It does not provide information about prognosis. Factors associated with pleural mesothelioma prognosis include: functional status, blood counts, histology (epithelial best vs fibrosarcomatous poorest), and tumor size (degree of involvement of pleural cavity). Several new trials. ...Read more
Interesting tumor: Overally, neuroendocrine tumors are often capable of over-producing hormones that your body naturally makes. Islet cells are cells that are naturally present in the pancreas and produce a number of hormones, most notably insulin. Insulin helps you break down and digest sugars. Patients with an islet cell tumor can produce too much Insulin resulting in weight & gain and low blood sugars. ...Read moreSee 1 more doctor answer
The gonads produce: Sperm in men (&testosterone) and eggs/ova in women (& estrogens), and these are also the sites of germ cell tumors. Outside the gonads, the mediastinum and brain (pineal) are the most common extragonadal sites. These are known to produce markers (hcg, alphafeto-protein) and responsve and curable with chemotherapy. Hope this helps. ...Read moreSee 1 more doctor answer
What is life expectancy of small cell neuroendrocrine carcinoma that metastizied to the brain (35 tumors) and spinal fluid (3 tumors)?
Metastatic brain ca: Poor prognosis. 6-8 months or less especially if more than one. ...Read more
Rare family: This is a family of tumors that can be diagnosed by a pathologist (i suggest you get a consensus from 3 of us) that resemble to some degree the gametes and/or the cells of the unborn child. They run from totally benign to very malignant; thankfully today's treatment produces many good responses. ...Read moreSee 1 more doctor answer
Tumor definition: Tumors are growths of tissue - like fat or epithelial lining cells that grow uncontrollably and can be hadmless if benign or dangerous if malignant like a colon or breast cancer. Your doctor will perform a biopsy and send the tissue to a pathologist who can diagnose the tumor and recommend curative or palliative follow up. ...Read more
Pseudotumor cerebri : From the mayo clinic pseudotumor cerebri (soo-doh-too-mur ser-uh-bry) occurs when the pressure inside your skull (intracranial pressure) increases for no obvious reason. Symptoms mimic those of a brain tumor, but no tumor is present. Pseudotumor cerebri can occur in children and adults, but it's most common in obese women of childbearing age. ...Read more
Review and discuss: Tumor boards are part of certified cancer programs all over the country. They usually have the surgeons, radiation and medical oncologists present. Also primary docs, pathologists, and other specialists are present. Nuses, palliative care teams and other support members are there. A patient ' s case is discussed from top to bottom, and a treatment plan is made with input from this team. ...Read more
"Relapse": Cancers that are treated can recur in one of two general ways locally or systemically. A local recurrence can often be retreated with surgery or radiotherapy. Systemic recurrence with tumor developing in distant organs is often managed with chemotherapy. ...Read moreSee 1 more doctor answer
No single answer: Tumors can feel soft or hard and may be painless or painful, depending on the type and location. Sometimes they are associated with changes to the overlying skin. A physician can check any skin spot or lump that is tender, itching, oozing, scaly, doesn't heal, has irregular color, swollen, is enlarging, or any other changes that worry you and make suggestions for further evaluation. ...Read more
Benign and malignant: Tumor refers to an overgrowth of tissue in a selected area. Benign tumors occur in the uterus as fibroids and in breast as fibroadenoma due to hormone stimulation. They do not convert or metastasize. The malignant tumors have oncogene transformations that allow rapid mitotic changes, and produce matrix metalloproteinase for invasion and telomerase activity for immortality. ...Read more
Depends on site: A 12x 8 mm lesion is about 1/2 inch in size. If in pancreas it is dangerous, In lung it can be resected. If if muscle and malignant it can easily be removed. The aggressiveness also depends on the histologic grading where a low grade tumor can be cured and a high grade lesion has to be treated more aggressively. ...Read more
Not CA, can get big: Cancers (malignant) tumors lose normal control with other cells, have unrestricted growth; they can enlarge, spread by blood or lymph. Can be fatal. Benign tumors are abnormal, but not cancers. Can get big, but don't spread by blood or lymph. Generally not fatal, although benign brain tumors can cause a lot of trouble-not much room to spare in the skull. ...Read moreSee 1 more doctor answer
Hard to say: There are many tumors that can occur in this area. Some are benign. Some are related the thyroid tissue, and some are related to the thymus. Lymphomas and lung cancers are just some of the other types. All have different outcomes. ...Read more
Variable by biology.: "tumors" can be either benign or malignant. Those that are malignant have the ability to grow and spread. Malignant neoplasms/tumors often invade adjacent normal tissues and are firm with irregular borders. They sometimes invade / surround nerves and can be associated with pain. Location in the body can be important as well. Hope that this helps. ...Read more
Viral associated: Many disorders have organisms that lead to malignant transformation. When hepatitits C causes cirrhosis one finds hepatomas developing. Gastric inflammation with helicobacter pylori lead to gastric and distal esophageal carcinomas. Aids immunodeficiency is associated with herpes 8 leading to cutaneous Kaposi sarcoma and inflammatory bowel disease has a high association with colon cancer. ...Read more
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