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Doctor insights on: Explain The Condition Called Acute Fatty Liver Of Pregnancy

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Explain the condition called acute fatty liver of pregnancy.?

Explain the condition called acute fatty liver of pregnancy.?

Fatty liver: It is a rare medical condition that relates to a lack of enzyme in the mytochondria that is involved in metabolism of fat. As a result fat buils in liver cells leading to acute liver failure which is fatal in high percentage. The only treatment is delivery and intensive care measures to preserve liver function. ...Read more

Dr. James Lin
2 doctors shared insights

Liver (Definition)

This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more


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What is acute fatty liver of pregnancy?

What is acute fatty liver of pregnancy?

Fatty liver: Acute fatty liver of pregnancy (aflp) is a rare, potentially fatal complication that occurs in the third trimester or early postpartum period. Although the exact pathogenesis is unknown, this disease has been linked to an abnormality in fetal fatty acid metabolism. Early diagnosis of aflp sometimes can be difficult because it shares features with other common conditions such as pre-eclampsia, vira. ...Read more

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How bad is acute fatty liver of pregnancy?

How bad is acute fatty liver of pregnancy?

Fatty liver/pregnanc: Is a real life threatening condition which occurs in third trimester or immediately following delivery it is caused by fatty acid metabolism disturbed by mitpchondria in the mother due to deficiency in lchad, (long chain 3hydroxy-co enzymea dehydrogenase) enzyme. Condition used to be thought fatal in the past but aggressive treatment by stabilising mother with support with IV fluids and blood prod. ...Read more

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How do you fix acute fatty liver of pregnancy?

How do you fix acute fatty liver of pregnancy?

Delivery: The cause is not well understood and delivery is the only chance to cure it. Rarely, it can get very severe quickly in pregnancy. ...Read more

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How common is it for somebody to get acute fatty liver of pregnancy?

How common is it for somebody to get acute fatty liver of pregnancy?

Rare: Acute fatty liver of pregnancy is rare. It has an estimated incidence of 1 in 7000 to 1 in 20, 000 deliveries. It is more common in patients with multiple gestations and maybe in women who are underweight. ...Read more

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Are some people more prone to getting acute fatty liver of pregnancy?

Are some people more prone to getting acute fatty liver of pregnancy?

Yes: Anyone who has had acute fatty liver of pregnancy (AFP) is at about a 25% risk for recurrence with future pregnancies. The initial episode appears to have a genetic predisposition due to an autosomal recessive gene defect. There is no current recommendation to screen for this genetic defect. The incidence of AFP is around 1 in 10, 000 pregnancies. ...Read more

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Do lots of people get acute fatty liver of pregnancy, or is it unusual?

Do lots of people get acute fatty liver of pregnancy, or is it unusual?

Uncommon: Acute fatty liver of pregnancy (AFP) is rare, occurring in about 1 in 10, 000 pregnancies. It is quite serious and can be fatal (to mom and / or baby) - good outcomes require prompt diagnosis and treatment, which usually incudes delivery of the baby as soon as the mother is stable. Recurrance risk is about 25% for subsequent pregnancies. ...Read more

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Suspecting acute fatty liver of pregnancy. What will do this to my wife?

Suspecting acute fatty liver of pregnancy. What will do this to my wife?

Serious condition: Acute fatty liver of pregnancy is a serious condition. It can be life threatening to both mother and baby. Treatment is immediate delivery. Unfourtunately, it can recur in the subsequent pregnancy. So, recommendation is to avoid future pregnancy. ...Read more

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What is the treatment for acute fatty liver of pregnancy?

Delivery of baby: Because the patient usually presents with liver failure, kidney failure, and whole host of associated potentially life threatening conditions, the best option is to get the baby delivered and then deal with all of the maternal complications. Maternal and fetal mortality approaches 25% and may even require liver transplant for the mother. ...Read more

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Doctor diagnosed acute fatty liver of pregnancy. What will do this to my wife?

Fatty liver/pregnanc: Is a real life threatening condition which occurs in third trimester or immediately following delivery it is caused by fatty acid metabolism disturbed by mitpchondria in the mother due to deficiency in lchad, (long chain 3hydroxy-co enzymea dehydrogenase) enzyme. Condition used to be thought fatal in the past but aggressive treatment by stabilising mother with support with IV fluids and blood prod. ...Read more

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Can fatty liver disease affect home pregnancy tests results?

Can fatty liver disease affect home pregnancy tests results?

Fatty liver: Fatty liver does not affect he pregnancy test results. Fatty liver is. Radiologic diagnosis seen on ct scan or sonogram. It does not affect lab values on less it progresses to cirrhosis but that is rare and takes a long time ...Read more

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I have cirrhosis & fatty liver disease been askd 2 do a study called placebo controlled trial evaluating the safety of GS-6624.should l try it or not?

I have cirrhosis & fatty liver disease been askd 2 do a study called placebo controlled trial evaluating the safety of GS-6624.should l try it or not?

Your decision: Research studies done that follow ethical guidelines have some safety guidelines however possible adverse effects must be discussed and participation benefits. ...Read more

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Fatty liver of pregnancy fatal?

Fatty liver of pregnancy fatal?

Possible: Most fatty liver of pregnancy resolves without problems, a very small number of pts can progress to cirrhosis and liver failure. ...Read more

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What are the causes of a fatty liver of pregnancy?

What are the causes of a fatty liver of pregnancy?

Enzyme deficiency: The association of cases of acute fatty liver of pregnancy with one of the inherited defects in mitochondrial beta-oxidation of fatty acids (the acronym for which is lchad), suggests that some affected women and their fetuses might have an inherited enzyme deficiency in beta-oxidation that predisposes the mother to this disorder. ...Read more

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Non alcoholic fatty liver and pregnancy, what to do?

Non alcoholic fatty liver and pregnancy, what to do?

Talk to OB and liver: specialist. Most cases of non-alcoholic liver disease are related to obesity and/or diabetes, both of which can complicate pregnancy, particularly in a woman over the age of 35. You should see an OB provider with experience in high-risk pregnancies, and consultation with a liver specialist would be reasonable as well. The further weight gain associated with pregnancy may cause problems. ...Read more

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What is the cause of a fatty liver in pregnancy?

Enzyme deficiency: The association of cases of acute fatty liver of pregnancy with one of the inherited defects in mitochondrial beta-oxidation of fatty acids (the acronym for which is lchad), suggests that some affected women and their fetuses might have an inherited enzyme deficiency in beta-oxidation that predisposes the mother to this disorder. ...Read more

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Will fatty liver affect my developing baby during my pregnancy?

Will fatty liver affect my developing baby during my pregnancy?

Fetal liver: Acute fatty liver of pregnancy (aflp) is a rare, potentially fatal complication that occurs in the third trimester or early postpartum period. Although the exact pathogenesis is unknown, this disease has been linked to an abnormality in fetal fatty acid metabolism. Early diagnosis of aflp sometimes can be difficult because it shares features with other common conditions such as pre-eclampsia, vira. ...Read more

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I would like to know if fatty liver will affect my pregnancy and my baby?

I would like to know if fatty liver will affect my pregnancy and my baby?

From the cause!: If you are obese, or have diabetes, or drink too much (the major causes for fatty liver) it will certainly affect the child and pregnancy itself. Ask your doctor for the reasons you have the condition. ...Read more

Dr. Andrew Berry
4 doctors shared insights

Pregnancy (Definition)

When your due date arrives, you will be more than ready to have your baby! Most women deliver the baby somewhere between 37 and 42 weeks. According to the American College of Obstetricians and Gynecologists, only 5% of babies arrive on the exact due date. Approximately 7% of babies are not delivered by 42 weeks, and when that happens, it is referred to ...Read more


Dr. Tiffanie Noonan
1 doctor shared a insight

Fatty Liver (Definition)

A condition where fat makes up more than 5% to 10% of the weight of your liver/ In some cases, this disease can ...Read more