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Doctor insights on: Experience Agitation Anxiety Pristiq

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Is it normal to experience horrible agitation and anxiety with pristiq?

Is it normal to experience horrible agitation and anxiety with pristiq?

It's not "normal": Not in the true sense of the word normal. It certainly can happen with Pristiq and a number of other antidepressants as well. If you did not have severe anxiety and agitation prior to taking Pristiq and it appeared when first taking Pristiq it is most certainly a side effect of that medication. That requires immediate stopping of that medication. No, it's not normal and it is not common either. ...Read more

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Dr. Ravi Chand
168 doctors shared insights

Pristiq (Definition)

Also called desvenlafaxine, is an antidepressant of the serotonin-norepinephrine reuptake inhibitors, developed by wyeth co. It is the synthetic form of the major active metabolite Effexor (venlafaxine). Can cause nausea, dizziness, constipation, sleep problems, decrease appetite, night terrors, anxiety ...Read more


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I have been taking 5-htp 100mg daily and 25mg pristiq for 4 weeks and starting to feel agitated, short of breath, tired .and a bit dizzy. ?

I have been taking 5-htp 100mg daily and 25mg pristiq for 4 weeks and starting to feel agitated, short of breath, tired .and a bit dizzy.  ?

More needs to be: known about 5-HTP before recommending its use. There have been recent reports of eosinophilia myalgia syndrome associated with its use or contamination. You can read about this on Web-MD. Pristiq can also cause a similar set of side effects in a small minority of people.Also starting two serotonergic agents at the same time is not advised. (increased risk of serotonergic syndrome) Ask your doctor. ...Read more

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I've been taking Pristiq for years with results, tried to get off of it twice but anxiety returned. Can Pristiq be taken as long as needed? For life?

I've been taking Pristiq for years with results, tried to get off of it twice but anxiety returned. Can Pristiq be taken as long as needed? For life?

Yes: Am not aware of any studies or reports showing harm from long-term use of Pristiq. If anything significant appears, doctors are notified immediately by the drug company and FDA. Keep follow-up appointments with your prescribing doctor and enjoy feeling better! ...Read more

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I have bad social anxiety and g.A.D. Is there any medication to prevent chronic blushing? Currently on pristiq(50mg)

I have bad social anxiety and g.A.D. Is there any medication to prevent chronic blushing? Currently on pristiq(50mg)

Behavioral Path: People struggling w/ social anxiety often get hyperfocused on the physical symptoms they experience in dreaded soc situations. This serves 2 magnifiy the intense discomfort that lies at heart of soc anx, viz, discomfort associated w/ the fear of embarrassing urself. Paradoxically, one way 2 "bust your shame" = If u were 2 make urself blush even harderin social situations & draw attn 2 that fact! ...Read more

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I was prescribed pristiq for my severe anxiety. My first day of taking it was today. I'm feeling really tired well more than usual is it a side effect?

I was prescribed pristiq for my severe anxiety. My first day of taking it was today. I'm feeling really tired well more than usual is it a side effect?

Pristiq: Fairly common & temporary side-effect. Talk to your doctor about possibly adjusting the timing of taking the medication so that sedation occur while u r asleep at night. ...Read more

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50mg pristiq (depression anxiety) seemed to lose effectiveness after 3 months 100 stopped working after another 3 on 150 now will this keep happening?

Consider change: There is no evidence that anything over 100mg has more effectiveness in studies. MDs will try higher dosages as tolerability allows as off label use. I would consider adding a second medication depending on what residual symptoms recur, or try adding deplin. ...Read more

Dr. Heidi Fowler
3,036 doctors shared insights

Anxiety (Definition)

Anxiety is a general term for several disorders that cause nervousness, fear, apprehension, and worrying. These disorders affect how we feel and behave, and they can manifest real physical symptoms. Mild anxiety is vague and unsettling, while severe anxiety can be extremely debilitating, having a serious ...Read more


Dr. Alan Ali
433 doctors shared insights

Agitation (Definition)

Agitation is an unpleasant state of extreme arousal (stirred up or excited), ...Read more