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Doctor insights on: Exocrine Pancreatic Insufficiency

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Is adrenal insufficiency hereditary?

Is adrenal insufficiency hereditary?

It can be.: One cause of adrenal insufficiency, addison's disease, is an auto-immune disorder. The immune system mistakenly makes antibodies targeting one or more proteins in the adrenal cortex, and winds up destroying the adrenal cortex, so that the adrenals can no longer make cortisol, or other hormones. As is true for most auto-immune disorders, a tendency to develop addison's can run in families. ...Read more

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Dr. Tiffanie Noonan
3 doctors shared insights

Pancreas (Definition)

Abdominal organ. It is digestive organ: it secretes enzymes into the small bowel which break down food and help its absorption. It is also an endocrine organ: it produces hormones involved in sugar control and control of digestion. Insulin is one of these hormones. Diabetics either lack Insulin (type 1 diabetes) or have inadequate ...Read more


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What is primary adrenal insufficiency (addisons disease)?

What is primary adrenal insufficiency (addisons disease)?

Adrenal cortex: The adrenal cortex makes lots of hormones. Very important are cortisol and aldosterone which help maintain life and salt balance. Addison's disease is caused by adrenal cortex damage rendering it unable to make these hormones anymore, mostly autoimmune cause in us. Patients often have a bronzed look. Hydrocortisone replacement is a lifesaving necessity. Fludrocortisone may also become necessary. ...Read more

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Can chronic mesenteric ischemia cause pancreatic insuffiency?

Can chronic mesenteric ischemia cause pancreatic insuffiency?

No.: Chronic mesenteric ischemia (cmi) occurs because of poor blood flow to the intestines, classically needing 2 out of 3 blood vessels to the gut with a significant narrowing. The usual symptoms of cmi are abdominal pain after meals, unintended weight loss, and a "fear of eating." the pancreas has such a rich blood supply that poor blood flow to it is not usually a problem. ...Read more

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Which test is better for diagnosing pancreas insufficiency: stool panc elastase or serum lipase/amylase? Would either diagnose pancreatic cancer?

Which test is better for diagnosing pancreas insufficiency: stool panc elastase or serum lipase/amylase? Would either diagnose pancreatic cancer?

Both together: Neither of the tests alone tells much. A combination of tests and exams will lead to diagnosis. Pancreatic cancer is not able to be ruled out by any test or imaging study. It can only be absolutely proven by some form of biopsy. A ct guided needle or egd with brushing a may be the only way to find it. ...Read more

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Does pancreatictist lead to pancreatic cancer ?

Does pancreatictist lead to pancreatic cancer  ?

Risk factors 2 watch: The risk of pancreatic cancer is increased in: tobacco smokers, being overweight, workplace exposure to certain chemicals, age >45, male gender, Afro American race, family history, genetic syndromes, diabetes, liver cirrhosis, chronic pancreatitis, possibly H.pylori, diets (rich in red meat, pork, processed meats), physical inactivity, heavy alcohol intake. Best to change what risks you can please ...Read more

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How accurate is pancreatic polypeptide In detecting pancreas tumor?

How accurate is pancreatic polypeptide
In detecting pancreas tumor?

NOT VERY!!!: Hi. Pancreatic polypeptide (PP) is NOT a screening test for pancreatic tumors. The only pancreatic cells that make PP are rare neuroendocrine cells in the Islets of Langerhans (an already tiny fraction of the pancreas). And those would be a TINY, TINY fraction of all pancreatic tumors. But hey, if it's a PP secreting neuroendocrine tumor of the pancreas, you'd have it dialed! Good luck! ...Read more

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What is 'pancreas biliary system'?

What is 'pancreas biliary system'?

Pancrease (pancrelipase) and biliar: The biliary system is a collection of tubes that end in gall bladder. The panreatic duct arises in pancreazse and joins common bile duct. This tube empties into small intestine just past end of stomach. ...Read more

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Panc elastase test shows insufficiency. Have fatty liver. Is pei cause of fatty liver? Is there connection between fatty liver and pancreatic cancer?

Panc elastase test shows insufficiency. Have fatty liver. Is pei cause of fatty liver? Is there connection between fatty liver and pancreatic cancer?

No, just description: Like most dx, just a label for a pattern, as judged by whatever metrics. Yes, there is observed relation between fatty liver ; developing liver cancer. Fatty liver most commonly due to persistent low-fat, hi-carb (i.e. All sugars, simple ; complex) foods. Liver, to protect rest of body from ?sugar (toxic), converts sugars into triglyceride fats. If can't export into external fat, then fatty liver. ...Read more

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Are pancreatic malignant tumors hypoechoic ?

Are pancreatic malignant tumors hypoechoic ?

Yes: The typical echogenicity of the pancreas is hyperechoic to adjacent fat. A hypoechoic mass within the pancreas can be benign or malignant. If you have a hypoechoic mass in the pancreas at age 30, you should undergo an MRI or ct of the abdomen to evaluate it further unless by ultrasound it is obviously cystic. ...Read more

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Is primary biliary cirrhosis hereditary?

Basically no: There's a pair of genes that carry the ability to develop the disease and these run in families, but it's not inherited like sickle cell, huntington's or some of the other familiar entities. http://www.medicalnewstoday.com/releases/151640.php. ...Read more

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Can pancreatic stenting for pancreatic divisum be dangerous?

Can pancreatic stenting for pancreatic divisum be dangerous?

Yes: Any instrumentation during an ERCP can cause acute pancreatitis. But procedures are done when reward>risk. ...Read more

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Can cryofibrinogenemia cause partial adrenal insufficiency?

Can cryofibrinogenemia cause partial adrenal insufficiency?

Theoretically yes: Cryofibrinogenemia increases your risk of arterial and venous clots. Antiphospholipid syndrome does the same thing, and is associated in rare cases with primary adrenal insufficiency. So it's theoretically possible that the same mechanism could cause adrenal insufficiency in cryofibrinogenemia, by clotting off the blood vessels that supply the adrenal glands. Good question! ...Read more

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What distinguishes pancreas, liver, colon, kidney, prostate and gallbladder cancers?

What distinguishes pancreas, liver, colon, kidney, prostate and gallbladder cancers?

Cure varies: Beyond the obvious differences in organ and cell type as well as the various treatment approaches, the most important patient difference is really the chance at cure. Early stage prostate and renal cell (kidney) cancers can be very curable. Even really early stage pancreatic cancers can be quite deadly. ...Read more

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How to diagnose pancreatic dysfunction? Amylase, lipase and insulin blood test?

History & physical: If the pancreas is inflamed or damaged, amylase and lipase are often up, and it's not subtle. If your pancreas isn't functioning properly, you'll be losing weight with no explanation and probably have diarrhea / steatorrhea. Your physician can check your stool for pancreatic enzymes. It's rare but with a suggestive history, a screen may show something that could respond to enzyme replacement. ...Read more

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What causes pancreatic ductal dilation?

What causes pancreatic ductal dilation?

Pancreatic duct dila: This can happen in chronic panceatitis, or if there is a pancreatic neoplasm ( tumor) . Sometimes there are benign tumors in the duct that can eventually become malignant so it is important to check them out. Technically gallstones that are stuck at the spincter of Vater causing pancreatitis can result in pancreatic duct dilatation as can inflammation post ERCP. ...Read more

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Are liver and pancreatic enzymes always elevated with liver and pancreatic cancer?

Are liver and pancreatic enzymes always elevated with liver and pancreatic cancer?

Short answer: No: Most often if a malignant mass presses on the ductal system of liver or panc. (see picture), it can cause abn. blood enzymes. If the mass is small and ducts drain, routine enzymes are usually normal. Gilbert Syndrome, a genetic abn. of up to 7% of folks, has the significance like your fingerprints, and is discussed nicely in: http://ghr.nlm.nih.gov/condition/gilbert-syndrome ...Read more

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Could pancreatic insufficiency be linked with trouble digesting sugars (bc of amylase), or only lipids?

Could pancreatic insufficiency be linked with trouble digesting sugars (bc of amylase), or only lipids?

Chronic pancreatitis: Chronic pancreatitis is hallmarked by problems absorbing fats (greasy, floating stools, sometimes gray or chalky). Problems with sugar metabolism come later as more of the pancreas is damaged. Chronic pancreatitis is further characterized less by low amylase production and more with lack of Insulin production and associated problems with glucagon. ...Read more

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