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Doctor insights on: Exercise Letrozole Breast Cancer

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Dr. Barry Rosen
1,337 doctors shared insights

Breast Cancer (Definition)

Breast cancer results when glandular cells lining the milk ducts and lobules of the human breast begin to grow in an unregulated manner. The growth occurs initially inside the ducts but eventually breaks outside into the breast tissue and ultimately spreads both to the lymph nodes in the armpit and via the bloodstream to other parts of the body. Because of the promoting affect of estrogen almost all breast cancer occurs in women and is a rarity in men. The unregulated growth is due to both inherited and acquired genetic defects. It is the most common malignancy in women but it often curable if found early and treated effectively with surgery, hormonal therapy, chemotherapy and targeted therapy, or a combination thereof. Early detection before the malignancy becomes large enough to be felt depends on mammography/sonography and MRI imaging of the breast ...Read more


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How long should a 50 yr old woman having breast cancer continue letrozole?

How long should a 50 yr old woman having breast cancer continue letrozole?

Tamoxifen is: Beneficial for 5 years, longer use provides no protection. Anastrazole and Letrozole are newer, are being tested beyond 5 yrs. These are indicated in tumors with + estrogen receptor. The use of these drugs for prevention without er+ breasst cancer is not proven. Protracted beyond 5 yrs of teh aromatase inhibitors is not yet proven. ...Read more

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How effective is letrozole (Femara) for treating breast cancer?

How effective is letrozole (Femara) for treating breast cancer?

Variable: Depends on 1) whether the tumor is estrogen receptor positive, 2) stage of the cancer. If metastatic, it works better for bone and soft tissue metastases and not very well for liver and lung metastasizes. Often used as an adjuvant treatment after surgery and often with radiotherapy ...Read more

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Are there people who should not take femara (letrozole) for breast cancer?

Are there people who should not take femara (letrozole) for breast cancer?

Premenopausal women: This is an aromatase inhibitor. This class of drugs is not effective for premenopausal women. It is used in the adjuvant setting and occasionally for metastasis. ...Read more

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What is the percentage of her2 breast cancer recurring if I stop taking femara (letrozole) which I have been on for 2 1?

What is the percentage of her2 breast cancer recurring if I stop taking femara (letrozole) which I have been on for 2 1?

Talk to your onc: Your oncologist would be the best one to answer this question. It's not a good idea to stop taking med without a discussion with the prescribing physician, especially when cancer is involved. ...Read more

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What is the percentage of her2 breast cancer recurring after 3 years with 2 1/2 years on femara (letrozole). I want to stop the femara (letrozole) due to the side effects.?

Hard to say: Hard to say without more details. You are lucky in a way to have a tumor that. Can be attacked with chemo, herceptin, (trastuzumab) and hormone blockade. Not all patients tolerate femara. There are other ai drugs and other options. Talk to your oncologist for options. ...Read more

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I'm just after an op for breast cancer grad3 and I have been told I have non Hopkins lymphoma and basilar migraine and letrozole ?

I'm just after an op for breast cancer grad3 and I have been told I have non Hopkins lymphoma and  basilar migraine and letrozole ?

Very complicated!: It sounds like you have 2 different cancers: 1. Breast cancer, and 2. Non-Hodgkins lymphoma. Letrozole is a medication used to treat breast cancer when the tumor has the estrogen receptor. It does not treat lymphoma. You can ask your doctor what treatment is planned for each cancer. Best of luck to you! ...Read more

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Can femara (letrozole) (used for breast cancer) have gum bleeding as a side effect ?

Can femara (letrozole) (used for breast cancer) have gum bleeding as a side effect ?

Controllable w-floss: So vascularized with blood vessels, gums look pink to red. Hormones and medications can make them "hyper-reactive" to plaque setting off an immune response that includes bleeding. Additionally, meds that cause dry mouth can increase plaque levels by reducing the self cleansing (plaque diluting) action of saliva. Try flossing, accurately and carefully twice a day. Skipping a single day =bleed. ...Read more

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Can i take phentermine to lose weight while taking femara (letrozole) after surgery for breast cancer?

Ask your oncologist: Letroaole (femara) is an aramatase inhibitor blocks estrogen production , may gain , Phentermine has amphetamine like effects , has several side effects , may inter react with Femara (letrozole) , only your doctor can advise its use. ...Read more

Dr. Barry Rosen
4,223 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


Dr. Ana Adelstein
74 doctors shared insights

Letrozole (Definition)

Letrozole is a commonly used medicine for the prevention/treatment of certain types of breast cancer. It is a safe medicine. It prevents the conversion of male to female hormones. It is also commonly used now for fertility treatment. It can help ovulation and can help a woman make an extra egg sometimes. It is often used instead of Clomid (clomiphene) for fertility treatment ...Read more