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Doctor insights on: Exchange Transfusion Complications

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What is the definition or description of: exchange transfusion?

What is the definition or description of: exchange transfusion?

Exchange your blood: Exchange transfusion describes a particular type of transfusion where the patient's blood is filtered such that the abnormal components are removed (red blood cells or platelets) and then the patient receives those components back from a donor transfusion. In other words, you exchange whatever your have that is defective for a working component from a donor. ...Read more

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Dr. Juan Merayo-Rodriguez
6 doctors shared insights

Exchange Transfusion (Definition)

Exchange transfusion describes a particular type of transfusion where the patient's blood is filtered such that the abnormal components are removed (red blood cells or platelets) and then the patient receives those components back from a donor transfusion. In other words, you exchange whatever your have that is defective for a working ...Read more


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If an rh-positive baby is suffering from erythroblastosis fetalis. An exchange transfusion is performed, why?

If an rh-positive baby is suffering from erythroblastosis fetalis. An exchange transfusion is performed, why?

Increase RBC mass: Most likely the mother is Rh neg. and has made anti-Rh antibodies destroying baby's Rh pos. red cells. Exchange transfusion to the baby with Rh neg. blood will prevent hemolysis or transfused blood and increase oxygen capacity for the newborn. This process will also decrease the amount of bilirubin in baby's plasma and prevent kernicterus (yellow staining seen in parts of the brain) ...Read more

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An rh-positive baby is suffering from erythroblastosis fetalis. Why would an exchange transfusion be performed?

An rh-positive baby is suffering from erythroblastosis fetalis. Why would an exchange transfusion be performed?

Increase RBC mass: Most likely the mother is Rh neg. and has made anti-Rh antibodies destroying baby's Rh pos. red cells. Exchange transfusion to the baby with Rh neg. blood will prevent hemolysis or transfused blood and increase oxygen capacity for the newborn. This process will also decrease the amount of bilirubin in baby's plasma and prevent kernicterus (yellow staining seen in parts of the brain) ...Read more

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The blood of choic for an exchange transfusion of an ABO hdn in a b-postive baby.. Is it o or b postive packed or whole blood..?

The blood of choic for an exchange transfusion of an ABO hdn in a b-postive baby.. Is it o or b postive packed or whole blood..?

Your doc knows: Usually it's reconstituted packed rbc with fresh frozen plasma, o neg, but it may be a whole blood as well (depends what is available, reconstitution of PRBC takes time). ...Read more

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How does exchange transfusion benefit sickle cell patients?

Removes sickle cells: Acute red cell exchange is useful in acute infarctive stroke, in acute chest and multi-organ failure syndromes. The process replaces sickled red blood cells with normal red blood cells. This procedure can also benefit certain patients on chronic transfusion plans by replacing sickled cells without increasing the viscosity of blood. ...Read more

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Why would they do exchange transfusion in sickle cell patients?

Why would they do exchange transfusion in sickle cell patients?

Exchange transfusion: Sickled cells can cause dangerous complications such as stroke, multiorgan failure syndrome, acute chest syndrome, hepatic sequestration crisis, and priapism. Exchange transfusions remove the patient's sickled blood and replace it with normal blood, reversing or lessening the effects of the aforementioned complications and allowing restoration of normal organ function. ...Read more

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Why do doctors cross-match an infant's and mother's blood before performing an exchange blood transfusion?

Why do doctors cross-match an infant's and mother's blood before performing an exchange blood transfusion?

ABO incompatability: Generally, if the mother is known to be of O blood type, we also check the baby's blood type as well as check for antibodies in the baby's blood (direct coombs test). If there is ABO incompatibility, positive coombs, high reticulocyte count and early jaundice then the baby will possibly require an exchange transfusion to prevent kernicterus ...Read more

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What are the complications from blood transfusions?

What are the complications from blood transfusions?

Potentially many: Though there are potentially many complictions thankfully the rate of complications is low. These can include reactions such as fevers, chills, allergic reactions to serious reactions such as hemolysis (blood destruction), infections (viruses, bacteria). ...Read more

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Do lots of people get complications from blood transfusions?

Do lots of people get complications from blood transfusions?

No: Patients getting a transfusion have their blood typed and examined for antibodies, and these are compared to the specific blood units being used for a transfusion. The blood being transfused is always screened for viral and bacterial contamination and used only if it is negative. There is less risk in a transfusion than in driving your car to work! ...Read more

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What are the long term complications of continuous blood transfusions?

What are the long term complications of continuous blood transfusions?

Iron overload: The main complication from long-term blood transfusion is the iron overload which can lead to organ damage. Although low now days, the risk of infection from blood-born agents may also be increased with long-term multiple blood transfusions. ...Read more

Dr. Juan Merayo-Rodriguez
318 doctors shared insights

Transfusions (Definition)

Sometimes babies are given whole blood to supply what they are lacking, and sometimes only components of blood, such as platelets or ...Read more