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Doctor insights on: Exchange Transfusion

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Dr. Juan Merayo-Rodriguez
6 doctors shared insights

Exchange Transfusion (Overview)

Exchange transfusion describes a particular type of transfusion where the patient's blood is filtered such that the abnormal components are removed (red blood cells or platelets) and then the patient receives those components back from a donor transfusion. In other words, you exchange whatever your have that is defective for a working component from a donor.


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What is the definition or description of: exchange transfusion?

What is the definition or description of: exchange transfusion?

Exchange your blood: Exchange transfusion describes a particular type of transfusion where the patient's blood is filtered such that the abnormal components are removed (red blood cells or platelets) and then the patient receives those components back from a donor transfusion. In other words, you exchange whatever your have that is defective for a working component from a donor. ...Read more

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Dr. Juan Merayo-Rodriguez
6 doctors shared insights

Exchange Transfusion (Overview)

Exchange transfusion describes a particular type of transfusion where the patient's blood is filtered such that the abnormal components are removed (red blood cells or platelets) and then the patient receives those components back from a donor transfusion. In other words, you exchange whatever your have that is defective for a working component from a donor.


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If an rh-positive baby is suffering from erythroblastosis fetalis. An exchange transfusion is performed, why?

If an rh-positive baby is suffering from erythroblastosis fetalis. An exchange transfusion is performed, why?

Increase RBC mass: Most likely the mother is Rh neg. and has made anti-Rh antibodies destroying baby's Rh pos. red cells. Exchange transfusion to the baby with Rh neg. blood will prevent hemolysis or transfused blood and increase oxygen capacity for the newborn. This process will also decrease the amount of bilirubin in baby's plasma and prevent kernicterus (yellow staining seen in parts of the brain) ...Read more

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An rh-positive baby is suffering from erythroblastosis fetalis. Why would an exchange transfusion be performed?

An rh-positive baby is suffering from erythroblastosis fetalis. Why would an exchange transfusion be performed?

Increase RBC mass: Most likely the mother is Rh neg. and has made anti-Rh antibodies destroying baby's Rh pos. red cells. Exchange transfusion to the baby with Rh neg. blood will prevent hemolysis or transfused blood and increase oxygen capacity for the newborn. This process will also decrease the amount of bilirubin in baby's plasma and prevent kernicterus (yellow staining seen in parts of the brain) ...Read more

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The blood of choic for an exchange transfusion of an ABO hdn in a b-postive baby.. Is it o or b postive packed or whole blood..?

The blood of choic for an exchange transfusion of an ABO hdn in a b-postive baby.. Is it o or b postive packed or whole blood..?

Your doc knows: Usually it's reconstituted packed rbc with fresh frozen plasma, o neg, but it may be a whole blood as well (depends what is available, reconstitution of PRBC takes time). ...Read more

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How does exchange transfusion benefit sickle cell patients?

Removes sickle cells: Acute red cell exchange is useful in acute infarctive stroke, in acute chest and multi-organ failure syndromes. The process replaces sickled red blood cells with normal red blood cells. This procedure can also benefit certain patients on chronic transfusion plans by replacing sickled cells without increasing the viscosity of blood. ...Read more

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Why would they do exchange transfusion in sickle cell patients?

Why would they do exchange transfusion in sickle cell patients?

Exchange transfusion: Sickled cells can cause dangerous complications such as stroke, multiorgan failure syndrome, acute chest syndrome, hepatic sequestration crisis, and priapism. Exchange transfusions remove the patient's sickled blood and replace it with normal blood, reversing or lessening the effects of the aforementioned complications and allowing restoration of normal organ function. ...Read more

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Why do doctors cross-match an infant's and mother's blood before performing an exchange blood transfusion?

Why do doctors cross-match an infant's and mother's blood before performing an exchange blood transfusion?

ABO incompatability: Generally, if the mother is known to be of O blood type, we also check the baby's blood type as well as check for antibodies in the baby's blood (direct coombs test). If there is ABO incompatibility, positive coombs, high reticulocyte count and early jaundice then the baby will possibly require an exchange transfusion to prevent kernicterus ...Read more

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What are some possible transfusion reactions?

What are some possible transfusion reactions?

Fever, itching, TACO: Acute reactions include: hemolytic;febrile, non-hemolytic;bacterial contamination;allergic / anaphylaxis; ransfusion-related acute lung injury (trali) transfusion-associated circulatory overload (taco) chronic reactions include: hemolytic; transfusion associated graft vs. Host disease (ta-gvhd);platelet refractoriness;post transfusion purpura;infectious disease;iron overload. ...Read more

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IGG. Transfusion for m-GUS disease?

No.: MGUS is not a disease per se. It is an abnormal antibody in blood by definition not caused by serious diseases like myeloma or lymphoma and therefore is not treated. It's importance is that MGUS has an annual cancer risk of 0.1 - 1%. ...Read more

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What are the benefits of a blood transfusion?

What are the benefits of a blood transfusion?

Treat anemia: People with significant anemia (low red blood cell count) have a reduced ability to deliver oxygen to the brain and other organs of the body. Correcting anemia with a blood transfusion can improve the symptoms of anemia such as fatigue and dizziness, and in more serious cases can be life-saving. ...Read more

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Dr. Juan Merayo-Rodriguez
318 doctors shared insights

Transfusions (Definition)

Sometimes babies are given whole blood to supply what they are lacking, and sometimes only components of blood, such as platelets or ...Read more