Doctor insights on:
Evolving Melanoma In Situ
Colon biopsy:huge tubulovillous adenoma with marked atypia, multi foci adenocarcinoma in situ &one tiny focus suggestive of micro invasion.Is it cancer?
Means localosed in place. Medical terms is for carcinoma "localized and did not spread out" it is really description of precancerous condition with bad name that disturbs many patients. Carcinoma in situ is not a killer. If left untreated will develop into invasive cancer ...Read more
What does "atypical intraepidermal melanocytic proliferation, suggestive of melanoma in situ" mean in diagnosis?
Viral insertion: DCIS is the earliest phase of transformation to malignancy developing in the ductal system before invasion into parenchyma has occurred. It is defined on mammo by clustered microcalcification. In general the long terminal repeat of the MMTV viral genome enters the ductal cell to initiate transformation. with time the cells become aggressive and invade basement membrane helped by the EBV virus ...Read more
Surgical excision: That is a pathological description of an excised lesion. There are two major ethos of treating a squamous cell cancers. The first is radiation, but this can leave permanent skin discoloration, and breakdown. Surgical excision with frozen echoing will help rule out. ...Read moreSee 1 more doctor answer
Yes: All melanomas are considered malignant however they have different levels of metastatic potential. This means that some melanomas have the ability to spread to other parts of the body while others, especially in situ melanomas, have little or no risk of metastasis. ...Read moreSee 1 more doctor answer
What is inverted papilloma with dysplasia and foci of in situto invasive squamous cell carcinoma(transitional)?
Please tell me if a lentiginous junctional dysplastic nevus is really melanoma in situ. My doctor won't respond.
There is a subtle di: Melanoma in situ is different than a dysplastic nevus, but it is a continuum. They both need to be treated in the same manner, re-excision with a negative margin.But remember one is a cancer the other one is a precursor of cancer. So it has long term health implications for health insurance etc. ...Read moreSee 1 more doctor answer
My pathology report states junctional and lentiginous melanocytic nevus, extending to the peripheral edge. Is this melanoma?.
Mole, not cancer: Here is a translation of your path report: Junctional- location as it relates to depth in the skin, the junction between epidermis and dermis. lentiginous- means flat dark spot, melanocytic- made up of pigment cells (melanocytes), nevus - a lesion that contains nevus cells a type of melanocyte, aka "mole". This is a benign spot that appears to have been completely removed. Not a malignancy. ...Read more
What does this mean? Inverted papilloma with dysplasia and foci of in situ invasive squamous cell carcinoma (transitional)?
Premalignant: An inverted papilloma is a tumor in which surface epithelial cells grow downward into the underlying supportive tissue. It may occur in the nose and/or sinuses or in the urinary tract (bladder, renal pelvis, ureter, urethra).. With dysplasia and in-situ squamous Ca this would probably be a premalignant sinus carcinoma bordering on squamous cell Ca needing resection. ...Read more
Nodular melanoma: Three of the four types of melanoma remain superficial in the epidermis and grow RADIALLY (laterally), often for several years, before entering the VERTICAL GROWTH PHASE where they grow downward and invade the dermis with the potential to metastasize. The fourth type of melanoma is nodular melanoma which STARTS in the vertical growth phase and can metastasize from the outset. ...Read moreSee 1 more doctor answer
Spread of cancer: Melanoma in situ is the term used to describe when the skin cancer only involves the surface (epidermis) of the skin and has not spread to any other tissues in the body; there is a 99.9% five year survival rate. Invasive melanoma indicates that the cancer has spread below the surface into the dermis of the skin. Metastatic melanoma indicates spread of the cancer to other areas in the body. ...Read moreSee 3 more doctor answers
Nearly 100% cure: If the area is removed in its entirety, most patients have essentially a 100% cure rate. The catch is that anybody who has 1 melanoma is at risk for developing other melanomas at other skin sites for the rest of their life. So even though the in situ melanoma site is essentially cured, you still have to avoid sun exposure and keep up with your skin screenings on an annual basis! ...Read moreSee 1 more doctor answer
Metastasis: Stage IV (4) melanoma is the highest stage that a melanoma can reach. It is diagnosed by finding distant spread or metastasis to other parts of the body. Stage is different from clark's levels and breslow levels, although these can impact lower stages. (ajcc cancer staging manual, 7th ed., 2010). ...Read moreSee 3 more doctor answers
Melanoma: Nodular melanoma typically skips the radial growth phase which predominates in the superficial spreading type of melanoma. However, that does not mean that it cannot change in diameter over 2 years. 2 years is way too long time to have a nodular melanoma. ...Read moreSee 1 more doctor answer
Invasive non keratinizing squamous cell carcinoma tongue showing nests of malignant squamous cells grade 3 prognosis?
Can be cured: If no nodes palpable and lesion localized, RT chemo can reduce size and position site for curative resection. Partial glossectomy after initial therapy. If larger and not responsive to chemo, Ive used hight dose MTX with citrovorum factor over 12 hrs. Most effective in presence of nodal disease Basic chemo is Platinum/Taxol + RT ...Read more
Father65,biopsy result of nasal polyps- Moderately differentiated infiltrating keratinizing squamous cell carcinoma with areas vasaloid. is it cancer?
Pathology moderate atypical dysplastic nevus, recommend further excision. Is this cancer/melanoma?
Yes: Common sites are the lymph nodes, lung and liver, but it can potentially spread anywhere. ...Read more
Pigmented lesion . In face..Recent increase size..Irregular border....Biopsy reveals malignant cells infiltration ...Whats diagnosis plz?
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