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Doctor insights on: Etoposide Allergy In Children

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Dr. John Chiu
2,638 Doctors shared insights

Allergies (Definition)

Allergies occur when your immune system is triggered by envirionmental factors it should ignore--for example, pollen in the air, or dander on a cat or dog--and creates cells to fight against them. An allergic reaction typically causes itching, congestion, or drainage, and ...Read more


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Who should not use Toposar (etoposide)?

Who should not use Toposar (etoposide)?

Toposar (etoposide): "TOPOSAR is contraindicated in patients who have demonstrated a previous hypersensitivity to etoposide or any component of the formulation." See: http://dailymed. Nlm. Nih. Gov/dailymed/drugInfo. Cfm? Setid=c9080cf5-4fc3-4cf9-a241-6e40a6fddc75 ...Read more

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Etoposide chemotherapy IV vs oral, what is the difference?

Commonly used IV: Etoposide is most effective when used Intravenously. Oral use required several days of therapy and offeres little advantage. So it is rarely used in modern oncology (It became popular for a few years in the 1990s. I no longer use it at all.. ...Read more

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What is the meaning of vp16, the chemotherapy agent etoposide?

Code designation: Vp-16 is the abbreviation of its code designation from the manufacturing company - bristol; - code designation vp-16-213, abbreviated as vp-16. No it is not named after somebody/chemist etc. ...Read more

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Why etoposide administered before ifosfamide in chemotherapy?

Why etoposide administered before ifosfamide in chemotherapy?

NO SPECIFIC REASON: Here are 3 possible reasons:
1) Most clinical trials use this sequence, although it has been given after in other studies as well
2) Etoposide is a shorter infusion 1-2 hours, Ifosfamide typically hours to 24 hrs, requiring monitoring of urine
3) Giving etoposide 1st also allows opportunity to give IV hydration prior to ifosfamide ...Read more

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Is there a drug interaction between etoposide and multivitamins?

Is there a drug interaction between etoposide and multivitamins?

Etoposide & vit E: Altho there are potential benefits of using vit e with cancer agents, there are also potential interactions with those that work by generating oxygen species to damage cancer dna & proteins. It is therefore advised not to use vitamin E during chemotherapy until it is researched further. Ask oncologist about other vitamins. ...Read more

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Please can you explain what is the major adverse effect of etoposide during chemotherapy?

Adverse reactions: There are many side effects for etoposide ranging from serious to common side effects. The more serious ones are bone marrow suppression which can cause anemia, low platelets and white cell count. Also major allergic reaction, seizures, low blood pressure, liver toxicity, lung disease, skin reactions, and visual problems. More common are tiredness, fevers, anorexia, diarrhea, stomach pain. ...Read more

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What is etoposide (also known as vp16)?

Chemotherapy drug: Etoposide is a chemotherapy drug based on compounds found in the American Mayapple. It acts by blocking enzymes (topoisomerases) that facilitate the unwinding of DNA - a process needed for DNA replication and cell division. It is toxic to cancer cells, which are characterized by relentless cell division. It is useful in a variety of malignancies ranging from lung cancer to leukemia. ...Read more

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Can pregnant women use Toposar (etoposide)?

Toposar (etoposide): Toposar (etoposide) is pregnancy Category D (Positive evidence of risk). ...Read more

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What should I expect on my third cycle of ifosfamide and etoposide?

Same as before.: There shouldn't be much difference in terms of symptoms from one cycle to the next. It is possible that your bone marrow may rebound more slowly after multiple cycles of treatment, and that can cause lower blood counts, but otherwise the symptoms and side effects should be similar to your prior 2 cycles. ...Read more

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Soon start my third cycle of ifosfamide and etoposide. How much more?

Depends...: Every chemotherapy regimen is different depending on what cancer you are treating and what stage the cancer is. Some regimens use a very limited number of cycles of Ifosfamide and Etoposide (i+e), other cancers require >10 cycles. It all depends. Ask your oncologist. ...Read more

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What is the drug interaction between etoposide and vitamins?

There really is: Limited defined interactions between etoposide and vitamins. There is a hypothetical concern about antioxidants like Co Q10, vitamins A, C and E and selenium preventing cell damage and thus making certain anticancer agents less effective but there is limited formal data in this regards. If you take supplements with anticancer meds review this with your doc and avoid "mega" doses. ...Read more

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Do etoposide and cisplatin cause alopecia?

Do etoposide and cisplatin cause alopecia?

Yes: Yes, the regimen will give you alopecia. ...Read more

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What is Toposar (etoposide)?

Toposar (etoposide): Toposar (etoposide) treats cancer of the testicles and small cell lung cancer. ...Read more

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Why does hair fall out when you take etoposide for chemo?

Why does hair fall out when you take etoposide for chemo?

DNA damage: Traditional chemotherapy like etoposide kills fast growing cells. Cancer cells are fast growing, so it attacks them. But, many other cells of our body are growing and dividing, like hair follicles and the linings from our mouth to our anus. Chemo kills these cells too; this explains hair loss, mouth sores, nausea, vomiting, and diarrhoea. ...Read more

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Please explain why does your hair fall out when you take etoposide for chemo?

Please explain why does your hair fall out when you take etoposide for chemo?

Chemo causes loss of: Chemo (drugs like Etoposide) stops the growth of cells in the body, especially in organs where there is rapid cell growth like blood and skin (and hair are part of skin cells). If there is no cell growth the hair become loose and fall out ...Read more

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ALL leukaemia 50+yrs old female patient took: 1500ml methotrexate, 2mg vincristine and 2 doses of 350mg etoposide. Is it the normal procedure or toxic?

ALL leukaemia 50+yrs old female patient took: 1500ml methotrexate, 2mg vincristine and 2 doses of 350mg etoposide. Is it the normal procedure or toxic?

Treatment for ALL?: Adult ALL is a difficult cancer to treat. The choice of drugs is often varied as more than one treatment programs have shown efficacy. Several drugs have been used and found to be useful. These include Methotrexate, Vincristine, Area-C, cyclophosphamide and Asparaginase.. The treatment success is dependent on the experience of the Treating team and the volume of patients treated at the Med- Cent ...Read more

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Can you have gastroparesis long term after treatment for testicular cancer with etoposide and cisplatin chemotherapy? What do you do for this if so?

Can you have gastroparesis long term after treatment for testicular cancer with etoposide and cisplatin chemotherapy? What do you do for this if so?

Not related: Gastroparesis is an ill defined entity of unknown cause. So I would not worry about it. Symtomatic treatment to control your acidity or anorexia may help. Do you have a gastroenterologist treating you for this problem? ...Read more

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Diagnoged with cutaneous tcell lymphoma. Treated with eletron beam. Interferon, gemcitabine, anthracycline, etoposide, procarbazine without improv. I'm 64 y?

Diagnoged with cutaneous tcell lymphoma. Treated with eletron beam. Interferon, gemcitabine, anthracycline, etoposide, procarbazine without improv. I'm 64 y?

There are new agents: There are several new agents for this disease. It is uncommon and you need a good assessment of the status of both your disease and your ability to take treatment. There are oral agents, antibodies, drugs like velcade (bortezomib) that might be helpful. I would suggest an evaluation by an oncologist who is familiar with this disease. ...Read more

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I had a chemo regimen of etoposide, methotrexate, actinomycin D/cyclophosphamide, and Vincristine. 4 yrs later I suffer from constant body pain, why?

I had a chemo regimen of etoposide, methotrexate, actinomycin D/cyclophosphamide, and Vincristine. 4 yrs later I suffer from constant body pain, why?

No online answer: EMA/CO is most often used for aggressive gestational trophoblastic neoplasia (GTN), usually choriocarcinoma. Long term diffuse body pains are not an expected side effect. A Gyn-oncologist should confirm there is no recurrence and then an evaluation from a good physical medicine, rheumatology, or even pain management doc will hopefully find the cause and a way to make you feel better. ...Read more

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Diagnoged with cutaneous tcell lymphoma nhl. Treated with eletron beam. Interferon, gemcitabine, anthracycline, etoposide, procarbazine. Nodules over body.?

Diagnoged with cutaneous tcell lymphoma nhl. Treated with eletron beam. Interferon, gemcitabine, anthracycline, etoposide, procarbazine. Nodules over body.?

Other options: There are multiple other options to include trials avaliable for treatment. Targeted therapy has been proven effective as well as immunotherapy. Would seek these out. ...Read more

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My mother was diagnosed march with LD small cell lung ca. She had 6 chemo vepesid (etoposide) and cisplatin. She was much?

My mother was diagnosed march with LD small cell lung ca. She had 6 chemo vepesid (etoposide) and cisplatin. She was much?

SCLC: Not sure what the question was, but prognosis overall is poor. Only about 1-10% of patients will be alive at 5 years. And the median survival is 12-18 months. Depends upon the extent of the disease at the time of treatment. ...Read more

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After treatment for testicular cancer with etoposide and cisplatin can you develop a delay in gastric emptying? Will this go away?

After treatment for testicular cancer with etoposide and cisplatin can you develop a delay in gastric emptying? Will this go away?

Good Q, but...: First, I would like to salute you for well coping with the care for testicular cancer. However, there would be no straight answer to your Q since life is a one-way street of accumulation, modification, & continuation. Hence, discuss this with your doc; that is most logical to do. Besides, exploring more on life reality will help further on how to cope as in http://formefirst. Com/onLifeBasics. Html. ...Read more

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Etoposide IV was given to my partner with carboplatin as a curative treatment for non-small cell lung cancer. Was this a standard treatment for this?

Etoposide IV was given to my partner with carboplatin as a curative treatment for non-small cell lung cancer. Was this a standard treatment for this?

Setting?: When you say "curative", you mean after surgery or concurrently with radiation? The choice of chemo depends on the situation, the doctor, and institutional or national standards. To answer your question, I normally would use carbo (or cisplatin)/etoposide in small cell lung cancer patients but can't say is a bad choice for nslc patients, especially with radiation. I've used it in that setting. ...Read more

Dr. Ira Friedlander
43 Doctors shared insights

Etoposide (Definition)

Etoposide is a cell division inhibitor which is a ...Read more


Dr. Jeffrey Wint
16 Doctors shared insights

Etopophos (Definition)

Etopophos is a cell division inhibitor which is a ...Read more