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Doctor insights on: Etoposide Allergy In Children

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Dr. John Chiu
2,628 Doctors shared insights

Allergies (Definition)

Allergies occur when your immune system is triggered by envirionmental factors it should ignore--for example, pollen in the air, or dander on a cat or dog--and creates cells to fight against them. An allergic reaction typically causes itching, congestion, or drainage, and ...Read more


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Who should not use Toposar (etoposide)?

Who should not use Toposar (etoposide)?

Toposar (etoposide): "TOPOSAR is contraindicated in patients who have demonstrated a previous hypersensitivity to etoposide or any component of the formulation." See: http://dailymed. Nlm. Nih. Gov/dailymed/drugInfo. Cfm? Setid=c9080cf5-4fc3-4cf9-a241-6e40a6fddc75 ...Read more

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Etoposide chemotherapy IV vs oral, what is the difference?

Commonly used IV: Etoposide is most effective when used Intravenously. Oral use required several days of therapy and offeres little advantage. So it is rarely used in modern oncology (It became popular for a few years in the 1990s. I no longer use it at all.. ...Read more

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What is the meaning of vp16, the chemotherapy agent etoposide?

Code designation: Vp-16 is the abbreviation of its code designation from the manufacturing company - bristol; - code designation vp-16-213, abbreviated as vp-16. No it is not named after somebody/chemist etc. ...Read more

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Why etoposide administered before ifosfamide in chemotherapy?

Why etoposide administered before ifosfamide in chemotherapy?

NO SPECIFIC REASON: Here are 3 possible reasons:
1) Most clinical trials use this sequence, although it has been given after in other studies as well
2) Etoposide is a shorter infusion 1-2 hours, Ifosfamide typically hours to 24 hrs, requiring monitoring of urine
3) Giving etoposide 1st also allows opportunity to give IV hydration prior to ifosfamide ...Read more

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Is there a drug interaction between etoposide and multivitamins?

Is there a drug interaction between etoposide and multivitamins?

Etoposide & vit E: Altho there are potential benefits of using vit e with cancer agents, there are also potential interactions with those that work by generating oxygen species to damage cancer dna & proteins. It is therefore advised not to use vitamin E during chemotherapy until it is researched further. Ask oncologist about other vitamins. ...Read more

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Please can you explain what is the major adverse effect of etoposide during chemotherapy?

Adverse reactions: There are many side effects for etoposide ranging from serious to common side effects. The more serious ones are bone marrow suppression which can cause anemia, low platelets and white cell count. Also major allergic reaction, seizures, low blood pressure, liver toxicity, lung disease, skin reactions, and visual problems. More common are tiredness, fevers, anorexia, diarrhea, stomach pain. ...Read more

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What is etoposide (also known as vp16)?

Chemotherapy drug: Etoposide is a chemotherapy drug based on compounds found in the American Mayapple. It acts by blocking enzymes (topoisomerases) that facilitate the unwinding of DNA - a process needed for DNA replication and cell division. It is toxic to cancer cells, which are characterized by relentless cell division. It is useful in a variety of malignancies ranging from lung cancer to leukemia. ...Read more

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Can pregnant women use Toposar (etoposide)?

Toposar (etoposide): Toposar (etoposide) is pregnancy Category D (Positive evidence of risk). ...Read more

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What should I expect on my third cycle of ifosfamide and etoposide?

Same as before.: There shouldn't be much difference in terms of symptoms from one cycle to the next. It is possible that your bone marrow may rebound more slowly after multiple cycles of treatment, and that can cause lower blood counts, but otherwise the symptoms and side effects should be similar to your prior 2 cycles. ...Read more

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Soon start my third cycle of ifosfamide and etoposide. How much more?

Depends...: Every chemotherapy regimen is different depending on what cancer you are treating and what stage the cancer is. Some regimens use a very limited number of cycles of Ifosfamide and Etoposide (i+e), other cancers require >10 cycles. It all depends. Ask your oncologist. ...Read more

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What is the drug interaction between etoposide and vitamins?

There really is: Limited defined interactions between etoposide and vitamins. There is a hypothetical concern about antioxidants like Co Q10, vitamins A, C and E and selenium preventing cell damage and thus making certain anticancer agents less effective but there is limited formal data in this regards. If you take supplements with anticancer meds review this with your doc and avoid "mega" doses. ...Read more

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Do etoposide and cisplatin cause alopecia?

Do etoposide and cisplatin cause alopecia?

Yes: Yes, the regimen will give you alopecia. ...Read more

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What is Toposar (etoposide)?

Toposar (etoposide): Toposar (etoposide) treats cancer of the testicles and small cell lung cancer. ...Read more

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Why does hair fall out when you take etoposide for chemo?

Why does hair fall out when you take etoposide for chemo?

DNA damage: Traditional chemotherapy like etoposide kills fast growing cells. Cancer cells are fast growing, so it attacks them. But, many other cells of our body are growing and dividing, like hair follicles and the linings from our mouth to our anus. Chemo kills these cells too; this explains hair loss, mouth sores, nausea, vomiting, and diarrhoea. ...Read more

Dr. Suzanne Galli
43 Doctors shared insights

Etoposide (Definition)

Etoposide is a cell division inhibitor which is a ...Read more


Dr. Milroy Samuel
16 Doctors shared insights

Etopophos (Definition)

Etopophos is a cell division inhibitor which is a ...Read more