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Doctor insights on: Etiology Or Pathophysiology Of Dementia

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Which type of neurological disease causes brain deterioration?

Which type of neurological disease causes brain deterioration?

Brain disease: Everything from genetic disorders and trauma to strokes and neurodegenerative diseases. ...Read more

Dr. Maureen Nash
1,478 doctors shared insights

Dementia (Definition)

A brain disorder that seriously affects a person’s ability to carry out daily activities. The most common form of dementia among older ...Read more


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What type of drugs cause dementia or alzheimers?

What type of drugs cause dementia or alzheimers?

Alcohol: We have no evidence alzheimer's is caused by a drug. However chronic excessive alcohol use is associated with dementia. There are negative cognitive effects of many other drugs including marijuana and opiates but few dementia syndromes described. To cause dementia there would need to be brain damage. ...Read more

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What symptoms precede the onset of alzheimer's or Parkinson's diseaase?

What symptoms precede the onset of alzheimer's or Parkinson's diseaase?

Different symptoms: Alzheimer's and parkinson's disease are quite different from each other. See these links for the 10 warning signs for each of these disorders. Alzheimer's: http://www.Alz.Org/alzheimers_disease_know_the_10_signs.Asp parkinson's: http://www.Parkinson.Org/parkinson-s-disease/pd-101/10-early-warning-signs-of-parkinson-s-disease. ...Read more

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Can a head injury cause or hasten Alzheimer's disease or other types of dementia?

Can a head injury cause or hasten Alzheimer's disease or other types of dementia?

The immediate effects of a head injury can include dementia symptoms, such as confusion, memory loss, and changes in speech, vision and personality: Depending on the severity of your injury, these symptoms may clear up quickly, last a long time or never go away completely. However, such symptoms that begin soon after your injury generally don't get worse over time as happens with Alzheimer's disease. Certain types of head injuries, however, may increase your risk of developing Alzheimer's disease or other dementias later in life. The greatest increase in future dementia risk seems to occur after a severe head injury that knocks you out for more than 24 hours. A moderately serious head injury that causes unconsciousness for more than 30 minutes, but less than 24 hours, also seems to increase risk to a smaller extent. There's no evidence that a single mild head injury that doesn't knock you out, or that knocks you out for less than 30 minutes, increases your risk of dementia. However, repeated mild injuries may increase risk of future problems with thinking and reasoning. You're likely at greatest risk of developing dementia or Alzheimer's later in life, post-head injury, if you also have other risk factors. For example, carrying one form of the apolipoprotein E (APOE) gene increases the risk of Alzheimer's in any individual. It's important to note that many people who sustain a severe head injury never develop Alzheimer's disease or later dementia. More research is needed to understand the link. ...Read more

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What sort of disease is cerebellar syndrome?

What sort of disease is cerebellar syndrome?

Incoordination: There are several features of people with cerebellar dysfunction with symptoms ranging from walking incoordination, hand incoordination, inability to do alternating movements, eye dysfunction and multiple others. Basically, your cerebellum coordinates the complex movements of your body and therefore cerebellar syndrome is a dysfunction of that coordination. It can be much more complex than this. ...Read more

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What type of mutation causes dementia with lewd bodies?

What type of mutation causes dementia with lewd bodies?

Allele, not a mutant: It's not well understood, but often appears in those w/ Parkinson's, so a link with the PARK11 gene has been studied. Like Alzheimer's or Parkinson's, most cases since not all end up w/ it LBD is not thought to be strongly inheredited. Yet LBD risk is heightened w/ inheritance of an allele. Info here: https://en.wikipedia.org/wiki/Dementia_with_Lewy_bodies ...Read more

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What are the causes of hypoxic ischemic encephalopathy?

What are the causes of  hypoxic ischemic encephalopathy?

Lack of oxygen/blood: Hypoxic-ischemic encepahalopathy is caused by a lack of oxygen and blood flow. This can occur around the time of birth, for example, from compression of the umbilical cord, or throughout life for example from cardiac arrest. ...Read more

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What causes the development of spongiform encephalopathy?

What causes the development of spongiform encephalopathy?

Prions: Prions are small abnormal proteins that can be transmitted by eating certain types of foods which usually contain parts of the central nervous system (i.e. The brain). The prions cause a reaction in the brain of the consumer which affect other normal proteins which leads to brain damage and progressive neuro-degeneration. ...Read more

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Is there any type of parasite that causes a nutrient deficiency, some type of anemia or vascular dementia?

Is there any type of parasite that causes a nutrient deficiency,  some type of anemia or vascular dementia?

Yes: There is a parasitic worm that lives inside pike and carp, and will lodge in the G.I. Tract and block absorption of vit b-12 causing anemia, and cognitive problems like a dementia. It is not like a stroke and is reversible if the vitamin b-12 is replaced, and the worm is dispatched. ...Read more

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Is alcohol a primary cause of anomic aphasia?

Is alcohol a primary cause of anomic aphasia?

Not usually: Alcohol addiction and withdrawal can lead to wernicke's aphasia which is usually characterized by lack of comprehension and fabulations. ...Read more

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What's mechanism of action of isoniazid in cerebellar ataxia in multiple sclerosis?

What's mechanism of action of isoniazid in cerebellar ataxia in multiple sclerosis?

Tough to treat: Cerebellar ataxia is a tough problem too control, but Isoniazid is not going to help. In fact, the only drug that has ever seemed useful symptomatically was buspar, and it helped only a small percentage. Better, if you have ms is to immediately treat all relapses, and use a potent disease modifying agent, such as tysabri, (natalizumab) gilenya, or tecfidera, as there is a chance that some problems may reverse. ...Read more

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What is the pathophysiology of chronic kidney disease?

What is the pathophysiology of chronic kidney disease?

Multiple reasons: Genetics Congenital disorders with altered kidney size, shape, function Medications auto immune disorders Diabetes These are common causes of alterations in kidney function that work by either harming the structure, blood flow or function of the kidney ...Read more

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Cause and treatment of multi infarct dementia?

Cause and treatment of multi infarct dementia?

Stroke is: The cause of multi-infarct dementia. Management is to prevent other strokes from occurring. See doctor regularly to keep blood pressure, cholesterol and diabetes (if you have it) under good control. If abnormal heart rhythm (atrial fibrillation) is present, then would need blood thinner to prevent blood clots in heart which can lead to stroke. ...Read more

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How common is dementia?

Common: Dementia is fairly common and the biggest risk factor is age. More than 1 out of 100 people aged 65 or less have dementia. Roughly 5 out of 100 of those aged 70, 10 of 100 aged 75, 25 of 100 aged 80 and roughly 45-50 out of 100 of those 85 years old and older have dementia. ...Read more

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What symptoms suggest dementia?

What symptoms suggest dementia?

See below: This is classical 10 warning signs and symptoms from web site of alzheimer association. http://www.alz.org/alzheimers_disease_know_the_10_signs.asp once you identify signs and symptoms, then please contact your primary care physician, geriatrician, neurologist or geriatric psychiatrist. ...Read more

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How do I avoid developing dementia?

Reduce risk: There may be ways to reduce the risk of developing dementia such as regular exercise and treating vascular risks such as hypertension, high cholesterol and diabetes. However, there is no way to absolutely prevent dementia (other than dying young, which is not a good option). ...Read more

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What do you recommend for dementia?

What do you recommend for dementia?

Depends: Treatment is tailored according to type of dementia, symptoms, cause etc. ...Read more

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Can overmethylation cause dementia?

Can overmethylation cause dementia?

No: Dementia is usually differentiated into two types: vascular type, and non-vascular type. Vascular dementia is due to disruption in the vascular supply causing degeneration of neurons. Non-vascular dementia, such as Alzheimer's dementia, Lewy body dementia are cause by mechanisms involve amyloid plaque depositions and neurofibrillary tangles, and accumulation of Lewy body in the neuron. ...Read more

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How do you know if you have dementia?

How do you know if you have dementia?

You don't!: There are many things that can cause memory problems! stress is one of the most common. If you have concerns, do not try to diagnose yourself! make an appointment with your family doc and if medically cleared, see a geriatric psychiatrist in your area. ...Read more

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What are the early symptoms of dementia?

What are the early symptoms of dementia?

It depends on Early!: Dementia is a syndrome presenting with significant decline in cognition, including short term memory, leading to behavioral problems and decline in ability to care for self. The onset is usually subtle, gradual and must be differentiated from other causes of imparement, like depression, delirium and normal aging. ...Read more

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I have most of the symptoms of dementia?

I have most of the symptoms of dementia?

First, see your: Family doctor to rule out any medical illnesses that can cause memory problems. If medically cleared, make an appointment with a geriatric psychiatrist for an evaluation. Memory problems can be caused by a number of things. The most important thing is to get the right diagnosis so you will get the right treatment! ...Read more

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Are there typical behaviors of dementia?

Are there typical behaviors of  dementia?

There are many: Dementia can be thought of as a cognitive disorder or as a behavioral illness. Nearly everyone with dementia will have behavior problems at some time. Psychomotor agitation, anxiety, sleep disturbances, appetite disturbances, depression, paranoia/delusions, hallucinations, aggression, mood lability, and apathy are some of the most common symptoms. Most of these symptoms are treatable. ...Read more

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What are the tests that indicate dementia?

What are the tests that indicate dementia?

Step by step: Good diagnosis starts with history and medical exams by your doctor or neurologist. If general medical is fine, usually neurologic exam and tests are geared toward ruling and diagnosis treatable forms of dementia. Early stages may not be evident on medical tests, and neuropsychological testing can play an important role in early diagnosis, treatment and differential with depression. ...Read more

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What are some of the symptoms of dementia?

What are some of the symptoms of dementia?

Memory impairment +: Memory impairment with aphasia, apraxia, agnosia or decreased executive functioning. ...Read more

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How can I reduce the severity of dementia?

Functioning changes: The severity of dementia cannot be changed currently but by changing a person's environment you can help a person be more functional. In early illness some dementia specific medications can slow the loss of functioning. ...Read more

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What are the classic symptoms of dementia?

Symptoms may vary: In each person, but they include memory loss, trouble communicating, difficulty learning or remembering new information, trouble planning or organizing, trouble with coordination or motor functions, personality changes, inability to reason, inappropriate behavior, paranoia, agitation and hallucinations. These must be severe enough to interfer with daily life. ...Read more

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What are the types of dementia you can get?

What are the types of dementia you can get?

There are many.: Alzheimer's dementia is the most common type of irreversible dementia. Others include multi-infarct or vascular dementia, lewy body dementia, frontotemporal dementias, huntington's disease, creutzfeld-jakob disease. Approximately 1 percent of dementia cases are reversible. They include operable brain tumors, vitamin B12 deficiency, thyroid disease, alcoholism or depression. ...Read more

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What happens at the end stages of dementia?

Infection: In severe dementia, alzheimer's, the patient becomes increasingly apathetic and withdrawn, more bed-ridden, and has increased inability to control bowel and bladder. Eventual infections arise, and most perish secondary to pneumonia. ...Read more

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What is the medical definition of dementia?

What is the medical definition of dementia?

A form of dementia: Dementia are conditions marked by decline in cognitive function & difficulty with daily activity.Alzheimer' s disease, characterized by problems with memory is one type. Exact cause unknown but good general health is better. Risk factors include old age & it runs in some families. Some reversible conditions such as depression or low sodium can mimic symptoms so careful diagnosis is the first step. ...Read more

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What different stages of dementia are there?

Seven: Different type of dementias will have different stages and the time course for each stage will vary per individual patient. There are technically 7 stages including pre-dementia, but in clinical practice doctors really focus on mild, moderate, to severity of symptoms. ...Read more

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Are intellectuals less likely to get dementia?

Are intellectuals less likely to get dementia?

With exercise: A combination of physical exercise plus mental challenges does appear to slow the onset and progress of dementia (but cannot prevent it). See http://www.Ncbi.Nlm.Nih.Gov/pmc/articles/pmc1151037/ the physical activity component is crucial, as the brain is itself a physical organ. Indeed it consumes 25% of our energy production, so it the organ most sensitive to energy depletion. ...Read more

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Can people develoup dementia in their twenties?

Very rare, but yes: Early-onset dementia can strike in the thirties and perhaps late twenties. This is especially true for adults with down's syndrome. It is quite rare in any case. Chemically induced brain damage from illicit drug/substance abuse can also present as dementia in young people. ...Read more

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What is the definition of degenerative dementia?

What is the definition of degenerative dementia?

Dementia: Degenerative dementia generally refers to non-reversible loss of cognitive functioning, typically due to certain diseases like Alzheimer's. Dementia of this type cannot be stopped and functioning will continue to decline with progression of disease. ...Read more