Doctor insights on:
Estrogen Uses Women
Tamoxifen is given to breast cancer patients to suppress estrogen or both estrogen & progesterone?
Estrogen: Tamoxifen is given to individuals with specific breast cancers that are driven to grow by the presence of estrogen receptors. Tamoxifen interferes with the activity of estrogen in the breast, preventing cancer growth. The role of Progesterone receptors is unclear, though Progesterone receptors in breast cancer are generally associated with estrogen receptors, making tamoxifen an effective therapy. ...Read moreSee 2 more doctor answers
Does topical estriol get converted into estradiol in women treated for menopause? Is estriol any safer than estradiol? Mammogram/breast exam is normal
NO; Yes: Estriol does not convert to other Estrogens in the body. It is safer because it's the weakest of the Estrogens and has no link to breast cancer. Studies suggest thta estriol has a protective effect. If used incorrectly, though, it can trigger hot flashes. ...Read moreSee 1 more doctor answer
Is combined tamoxifen plus hormonal therapy more effective in pre or postmenopausal women and why?
Tamoxifen: We don't give tamoxifen in combination with hormone replacement in the us. Occassionally use vaginal very low dose estrogen cream for vag dryness and tell pts to use a little as they can to relieve symptoms. Blocking hormones and giving them at same time does not make much sense. ...Read more
Varies: Estrogen levels vary between women and they vary all the time within the same women. There is a generally accepted range based on the time of the menstrual cycle. Women 12 year old woman have higher peak estrogen levels than 40 year old woman and vice versa. So that is a difficult question to answer and may not be as important as why levels change. ...Read more
When prometrium (micronized progesterone) stimulates instead of sedates a perimenopausal woman what should be taken? Estrogen in combo with prometrium (micronized progesterone)?
Go see your doctor: While our impression of estrogen for perimenopausal women has changed dramatically over the last decade, it still should be used for right reason, and sedation is not one of them. So go see your prescribing doctor & tell her/him about your side effects so that s/he can offer you some alternatives (rather than just throw more medications at you). ...Read more
Usually: Because the cream is applied where the effect is needed, there is less chance of estrogen entering the blood stream and traveling to other organ systems to cause unwanted effects. But any medication can have side effects regardless of whether it is taken internally or externally, orally or parentally so please discuss your concerns with your doctor. ...Read more
Not a good idea!: The use of hgh (human growth hormone) is not appropriate for use in treating menopausal symptoms (which I am assuming you are referring to). It would be more appropriate to talk with your doctor about the symptoms you are trying to treat and addressing them in a non-hormonal way if possible. The use of hgh, for example, will likely significantly impact your cholesterol levels in an adverse way! ...Read moreSee 1 more doctor answer
Yes: For woman with premature ovarian failure (pof), we recommend hormone replacement therapy, which includes both estrogen and progesterone. The addition of Progesterone is to regulate menstrual period and prevent uterine cancer. For woman desires for pregnancy, we may be able to reduce her fsh level and induce ovulation in some patients. ...Read moreSee 1 more doctor answer
By the follicle: An amazing dance of hormones coordinates the reproductive system. One of the thousands of egg sacs that are in the ovary matures each month during the reproductive years. During the first two weeks of the menstrual cycle, the follicle releases estradiol, a potent estrogen. After releasing its egg, the follicle becomes a corpus luteum and makes Progesterone instead. ...Read moreSee 1 more doctor answer
Is combined tamoxifen plus hormonal therapy better for breast cancer in pre or postmenopausal women?
Estrogen supression: In general, aromatase inhibitor is only indicated for postmenopausal women ;not for premenopausal; while on the other hand, tamoxifen can be given either in pre or postmenopausal. Only thing is that tamoxifen can cause a little bit higher risk for complication -i.e. Risk for blood clots and risk for develping uterine cancer- when used in older population- age of -65 Y.O. Or above. ...Read moreSee 2 more doctor answers
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