Doctor insights on:
Estrogen Secreting Tumors
Very uncommon: Typically abnormal bleeding is the presenting symptom. They are very uncommon. ...Read more
Tamoxifen: Tamoxifen has been the standard drug that blocks estrogen receptors in patients whose tumors are considered ER+ A new type of anti-estrogen drug appears to work better than the estrogen-blocking drug tamoxifen. Exemestane (Aromasin), belongs to a class of drugs called aromatase inhibitors. But, for exemestane to work in premenopausal women, the drug can only be given when ovarian function is being suppressed. The Aromatase inhibitors, work by preventing other hormones from changing into estrogen, which fuels certain cancer growths ...Read more
Over expression: A number of different malignancies have been associated with production of estrogen. Many are ovarian tumors such as granulosa cell tumors and thecomas. Estrogen-producing endometrioid adenocarcinoma resembling sex cord-stromal tumor of the ovary and Sertoli cell tumors of the testis, and adrenal tumors have also been reported to produce increased levels of estrogen. ...Read more
Breast Cancer?: Are you referring to an er positive breast tumor? If so, this means that the breast tumor has receptors to estrogen. The receptors stimulate the tumor to grow in the presence of estrogen. We use this to our advantage in treating these cancers by blocking the estrogen receptors. ...Read more
What effect will having an adrenal tumor that produces a lot of estrogen have on a female's growth if left untreated?
Take it out: It needs to come out - really rare and potentially malignant. High estrogen levels still increases risk for other cancers, particularly breast and endometrial. Additionally, for the girl, sexual maturity comes quickly, growth will be stunted due to acceleration of growth plate maturity leading to premature closure. Infertiility and other problems. ...Read more
On cabergoline not for tumor, will it increase progesterone & estrogen as I begin to ovulate more consistently.?
Why cabergoline: If it's not a tumor, it means that the tumor is too small to find or you have an elevated prolactin for another reason such as psychiatric meds. Otherwise, there's no need to take cabergoline. If your prolactin is elevated, and then lowered with cabergoline, you may have improvement in hormone secretion and more normal ovulation and possible fertility. ...Read more
I have elevated dhea levels (345) and low estrogen, I am 31 years old and do not have any tumors. Could birth control help balance this out?
If you mean DHEAS: Your level is normal. Why are you taking DHEA? It's metabolized to either cortisone, estrogen or testosterone and you can't control which one. Also, most of the DHEA pills don't really have much DHEA in them. You haven't provided enough facts to really tell you anything, Birth control isn't really used to "balance" anything WHy are you on estrogen and also BCP's? Talk w/your doctor, ...Read more
Can't estrogen blocking meds. Dbl. Mast., clean margins 1.2 cm tumor, no lymph node involv., oncodx score 2, estrogen/progesterone pos. % of return?
Less than 5%: With lesion smaller than 2 cm., negative nodes and ER PR pos. Most recurrences are in residual breast. Sine double mastectomy, any recurrence would be distant mets and with nature of primary lesion, the high risk factors of primary absent would minimaize recurrence. One could consider tamoxifen but I would hold off on meds especially with an oncodx score of 2 which suggests minimal recurrence. ...Read more
Mildly enlarged convex pituitary gland. Being referred to endocrinologist. What could cause this. Elevated prolactin, low estrogen. No discrete tumor.
Pit enlarged: Many causes and good discussion can be found at uptodate. Com May even be normal. ...Read more
Doctors, may you give me names of fibroids anti-tumour foods or foods that can help shrink tumors? And why is estrogen high on monthly periods? Thanks
Fruit & Veggies: Colorful fruit and veggies are rich in flavonoids which block an important enzyme in estrogen biosynthesis. Even if you're a strict vegan its hard to avoid the hormones in the food supply. Trying to be as close to your ideal weight (cut excess body fat), exercise, and eat healthy (fruits & veggies, limit meat/dairy) will help your fibroid situation alot (and will improve your overall health too! ...Read more
I'm having major left brest pain. Since my miscarriage 4mos ago my body can't seem to get better. But to the left brest, it's enlarged& so painful I had to go the the ed. I undersand I may have a brain tumor, is this all connected. My estrogen was 2.5, f
Breast cancer?: You should see a breast surgeon asap; what you describe sounds ominously like inflammatory or anaplastic breast cancer that metastasized to the brain! Please seek expert medical care to further investigate this possibility and assure that your health is in good shape. Best of luck! ...Read more
Mom died of breast cr @47 due to estrogen tumor. She smoked/on pill most of life/had a baby at 40. I don't smoke/or on pill. I am 40. Am I better off?
Always: Always better to avoid smoking...Always a good idea, with risk factors, to follow-up regularly with your family doc/internist/ob/gyn... ...Read more
What causes low blood level of dhea. I'm 25 female. Adrenal tumor maybe? I have high estrogen and chronic fatigue, body pain etc...
See endocrinologist: Dhea isn't a hormone we typically measure at random because it isn't as reliable as the longer 1/2 life of dheas. Likewise, we usually don't measure total estrogen as it isn't helpful. Dhea is most reliable when compared before and after IV acth during stim testing around other hormones. Adrenal insufficiency can't be identified with a random dhea. ...Read more
I have elevated prolactin, not due to pituitary tumor, will cabergoline enable thyroid and estrogen/progesterone ratio to all become balanced?
Probably: High prolactin can result from certain medications, narcotics, stress, as well as from pituitary tumors that are too small to see on imaging studies. High prolactin will cause female pituitary hormone levels to become abnormal, resulting in irregular periods or loss of periods. Cabergoline will lower prolactin and improve this imbalance. High prolactin does not typically cause abnormal thyroid. ...Read more
Foods rich in phytoestrogen, a natural estrogen, include soy products (tofu, soy milk, etc), whole grains and legumes, lignin-rich foods like flaxseeds, millet and barley.
Other foods have estrogenic effects, meaning that the body can "mistake" them for estrogen: fennel seed and cinnamon are examples. Women undergoing menopause may develop symptoms due to low estrogen, and these foods may help. ...Read more
No, but...: ...Alfalfa contains isoflavones which have a low and variable degree of estrogen like activity in animal models. One would have to consume a lot of alfalfa to have much of an effect, and there are side effects associated with this supplement which would need to be seriously considered first. ...Read more
Estroblend: black cohosh and isofavones are natural sources of phytoestrogens that help reduce hot flashes and night sweats.
Phytoestrogens: also called 'dietary estrogens', they are a diverse group of naturally occurring nonsteroidal plant compounds that, because of their structural similarity with Estradiol have the ability to cause estrogenic effects. ...Read more
Yes: Dhea is a male-type (androgenic) hormone from the adrenal glands which can be enzymatically converted to other androgens in your body, which can be converted to Estrogens by the hormone aromatase. Beware of marketing excesses that imply benefits from supplements which are unproven. ...Read more
Symptoms only: If you are still have menopausal symptoms (eg hot flashes, sweats) after age 60 than estrogen replacement therapy may still be indicated. However that is not the usual situation. Typically the risks of estrogen outweigh the benefits in women 60 and older. Estrogen replacement has been shown to increase the risk of heart attacks, strokes and breast cancer. While it can reduce the risk of bone loss. ...Read more
Complicated Question: From a symptomatic point of view, I many times see the exact oposite. Hormones such as cortisol, estradiol, estrone, estriol, testosterone, etc come from cholesterol via a specific pathway. Stress can increase cortisol levels, requiring a trasnformation from dhea to cortisol. This can lead to a reduction in estrogen because there is a reduced amount of "building" material to produce estrogen. ...Read more