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Doctor insights on: Estrogen Related Breast Cancer

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What is the role of estrogen in breast cancer?

What is the role of estrogen in breast cancer?

Stimulates the growt: About 80% of breast cancer are er positive which means that the cancer cells are stimulated to grow by estrogen in the body. Decreasing the estrogen levels with tamoxifen which is an estrogen blocker in premenopausal women and aromatase inhibitors which stop estrogen production in sites other than the ovaries in post menopausal women is an important treatment. ...Read more

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Dr. Barry Rosen
4,464 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Do high estrogen levels cause breast cancer in men?

Do high estrogen levels cause breast cancer in men?

IT'S A RISK FACTOR: Prolonged exposure to estrogen is a risk factor for breast cancer in men. Obesity, liver cirrhosis and high alcohol intake can lead to a high estrogen state. ...Read more

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Is it true that estrogen increases the risk of breast cancer?

Is it true that estrogen increases the risk of breast cancer?

HRT-yes: The use of hormone replacement therapy (hrt) for menopause has been shown to increase the risk for breast cancer when used longer than 5 years. Oral contraceptives do not have any relation nor increase in risk of breast cancer. ...Read more

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If my breast cancer feed off estrogen bein a female how can I reduce it in my body?

If my breast cancer feed off estrogen bein a female how can I reduce it in my body?

Anti-hormone drugs: If you have been diagnosed with hormone-receptor positive breast cancer, you should be on a medication to either block estrogen (tamoxifen) or, if you are post-menopausal, to decrease the level of estrogen in your body (letrozole, anastrazole, or exemestane). You can lose weight if you are obese, which will also decrease the estrogen in your body. However, anti-estrogen drugs are very important! ...Read more

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How long would I have to take estrogen before I start worrying bout breast cancer.?

How long would I have to take estrogen before I start worrying bout breast cancer.?

5 yrs or less: It has been shown that using hormone replacement therapy (hrt) can increase one's risk of breast cancer when taken for longer than 5 years. Because of this we no longer recommend taking hormones for long periods of time. Work with your gynecologist for options to deal with the symptoms of menopause. ...Read more

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If I had breast cancer, can I take estrogen in menopause?

If I had breast cancer, can I take estrogen in menopause?

Probably not: You should speak with your oncologist, however, Estrogens are usually not recommended if you have had breast cancer. ...Read more

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How do breast cancer anti estrogen pills work?

How do breast cancer anti estrogen pills work?

Starve tumor: Many tumors are fed by estrogen - the main female horomone. Anti-estrogen pills block the effects of estrogen (in a variety of different ways) and thereby starve the tumor from a vital growth factor. Even if you are postmenopausal (or even male) your body still produces estrogen in places like the adrenals and subcutaneous fat. ...Read more

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What is estrogen receptor positive breast cancer?

What is estrogen receptor positive breast cancer?

One with receptors.: These are tumors with estrogen receptors on them. This makes them susceptable to some chemotherapeutic agents, like tamoxifen. ...Read more

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What is meant by having estrogen receptor positive breast cancer?

What is meant by having estrogen receptor positive breast cancer?

Feeds the cancer: Most breast cancers are estrogen receptor positive. The cancer cells have receptors that fit the estrogen molecule that a body produces. Think: a lock and key - when estrogen binds to the receptor the tumor cell is stimulated to grow and divide. Er+ tumors can be blocked by tamoxifen and Arimidex (anastrozole) (and others) that interfere with this pathway. ...Read more

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Should a 65-year old woman with a family history of breast cancer continue estrogen?

Should a 65-year old woman with a family history of breast cancer continue estrogen?

Probably not.: This can increase the risk for some breast cancers and endometrial cancer. Having a family history does not help. However, low dose hormone replacement therapy may be possible. It would be wise to see your doctor to be sure. ...Read more

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If I have too much estrogen, or not enough progesterone, does that make me more susceptible to breast cancer?

If I have too much estrogen, or not enough progesterone, does that make me more susceptible to breast cancer?

Breast cancer risk: Maybe: some breast cancers take up estrogen as a sort of growth hormone to encourage growth, so too much estrogen can speed growth of these cancers. There is a very small increase in breast cancer risk with estrogen only given postmenopausally for the symptoms. Relative increase in Progesterone only is associated with some breast disorders also but cancer risk is unclear. ...Read more

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Im on estrogen pills how long should I take them before they run a risk of causing breast cancer and should they be took along?

Im on estrogen pills how long should I take them before they run a risk of causing breast cancer and should they be took along?

5 yrs or less: It has been shown that using hormone replacement therapy (hrt) can increase one's risk of breast cancer when taken for longer than 5 years. Because of this we no longer recommend taking hormones for long periods of time. Work with your gynecologist for options to deal with the symptoms of menopause. ...Read more

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How much estrogen gets into system using vaginal estrogen. Family history of breast cancer but not me. ?

How much estrogen gets into system using vaginal estrogen. Family history of breast cancer but not me. ?

Varies: Per the med insert: Premarin (conjugated estrogens) Vaginal Cream should not be used if you have unusual vaginal bleeding, have or had cancer, had a stroke or heart attack, have or had blood clots or liver problems, have a bleeding disorder, are allergic to any of its ingredients. This is due to significant absorption thru the vaginal mucosa which is dose dependent. Not the same risk for someone with family history only ...Read more

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What can I do for hot flashes can't take estrogen due to breast cancer in family I lost my mom to cancer?

What can I do for hot flashes can't take estrogen due to breast cancer in family I lost my mom to cancer?

SSRI;s: Selective Serotonin Reuptake Inhibitors (SSRI's) commonly known as a class of anti-depressants can be effective in minimizing hot flashes. Talk to your GYN MD about this and any other alternatives to estrogen Rx's that may be available. ...Read more

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Estrogen increases the risk of endometrial cancer, but does it increase the risk of breast cancer as well?

Estrogen increases the risk of endometrial cancer, but does it increase the risk of breast cancer as well?

Yes: Studies have shown an increase risk of breast cancer in patients treated with estrogen replacement. In fact, women at high risk for getting breast cancer are treated with tamoxifen or evista (raloxifene). Those drugs block the effect of estrogen on breast tissue. ...Read more

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I had a healthy shake that had soy lecithin in it will that cause high estrogen and breast cancer I'm worried?

I had a healthy shake that had soy lecithin in it will that cause high estrogen and breast cancer I'm worried?

A Shake: One shake is not going to alter your risk for anything. Soy lecithin is not a harmful substance anyway and is not a risk factor for breast cancer or any other disease. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. Get HPV vaccine. ...Read more

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Is cinnamon, ceylon type, in natural from safe for breast cancer survivors? I've read that it contains estrogen.

Is cinnamon, ceylon type, in natural from safe for breast cancer survivors? I've read that it contains estrogen.

Probably yes: Supposedly cinnamon does have some estrogenic properties, but there isn't any strong data out there that suggests those with estrogen receptor (+) breast cancer are at any significant risk with cinnamon consumption. I would caution you that in general, that more is rarely ever better, and that if you are "gung ho" about cinnamon supplementation that you be reasonable about your intake. ...Read more

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Could premerin homone replacement cause Paget breast cancer?

Unlikely: We think that combined hormone replacement including estrogen and Progesterone cause an increase in breast cancer of which paget's disease if the breast is a type. Premarin (conjugated estrogens) only contains estrogen. ...Read more

Dr. Mark Hoepfner
1,072 doctors shared insights

Breast Carcinoma (Definition)

Most breast cancers are carcinomas. This is a type of breast cancer. These cancers start in the cells that line organs and tissues. In fact, breast cancers are often a type of carcinoma called adenocarcinoma, which starts in cells that make glands (glandular tissue). Breast adenocarcinomas start in the ducts (the milk ducts) or ...Read more


Early Breast Development (Definition)

Is the technical name and means breast development earlier than "normal". Breast bud development can begin as early as 8 years old in some girls and is more usually between 10 and 12 years old. If there is actual breast development before age 8 then it can indicate a hormone problem (precocious puberty) and an endocrine appointment ...Read more