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Doctor insights on: Estrogen Receptor Negative Breast Cancer Can I Stay On My Patch

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Dr. Barry Rosen
1,336 doctors shared insights

Breast Cancer (Female) (Definition)

Breast cancer results when glandular cells lining the milk ducts and lobules of the human breast begin to grow in an unregulated manner. The growth occurs initially inside the ducts but eventually breaks outside into the breast tissue and ultimately spreads both to the lymph nodes in the armpit and via the bloodstream to other parts of the body. Because of the promoting affect of estrogen almost all breast cancer occurs in women and is a rarity in men. The unregulated growth is due to both inherited and acquired genetic defects. It is the most common malignancy in women but it often curable if found early and treated effectively with surgery, hormonal therapy, chemotherapy and targeted therapy, or a combination thereof. Early detection before the malignancy becomes large enough to be felt depends on mammography/sonography and MRI imaging of the breast on an annual basis. ...Read more


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What is estrogen receptor positive breast cancer?

What is estrogen receptor positive breast cancer?

One with receptors.: These are tumors with estrogen receptors on them. This makes them susceptable to some chemotherapeutic agents, like tamoxifen. ...Read more

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What is meant by having estrogen receptor positive breast cancer?

What is meant by having estrogen receptor positive breast cancer?

Feeds the cancer: Most breast cancers are estrogen receptor positive. The cancer cells have receptors that fit the estrogen molecule that a body produces. Think: a lock and key - when estrogen binds to the receptor the tumor cell is stimulated to grow and divide. Er+ tumors can be blocked by tamoxifen and Arimidex (anastrozole) (and others) that interfere with this pathway. ...Read more

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Natural breast cancer remedies? I learned that estrogen-receptor blockers treat cancer, but what are some ER blockers?

Natural breast cancer remedies? I learned that estrogen-receptor blockers treat cancer, but what are some ER blockers?

I am not sure what u: Mean by "natural" but if u mean something other than what ur oncologist recommends u are putting urself at great risk of failed treatment. There have been great strides made in the treatment of breast cancer and the current therapies are well documented and successfully employed with thousands of patients every year. Feel free to obtain a second opinion but seek a proven treatmnt, not snakeoil. ...Read more

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Estrogen receptor ER positive breast cancer adjuvant Taxol (paclitaxel) benefits?

Estrogen receptor ER positive breast cancer adjuvant Taxol (paclitaxel) benefits?

Get Oncotype: In order to answer this question, more details are needed (size of tumor, lymph node involvement, etc). A test that will help to decide if you need chemotherapy or not is the oncotype dx. I highly recommend you speak with your oncologist and even consider a 2nd opinion. ...Read more

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My mom had estrogen receptor-positive breast cancer, should I be taking birth control or getting pregnant?

It is your choice.: Even a family history of breast cancer should not stop you from having kids, especially if you are healthy and cancer free. There are also several treatment options for estrogen receptor-positive breast cancer, like tamoxifen. Birth control is, of course, an option if you do not feel ready to have children yet, regardless of your family history. Get counseling from your doctor to be sure. ...Read more

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How long would I have to take estrogen before I start worrying bout breast cancer.?

How long would I have to take estrogen before I start worrying bout breast cancer.?

5 yrs or less: It has been shown that using hormone replacement therapy (hrt) can increase one's risk of breast cancer when taken for longer than 5 years. Because of this we no longer recommend taking hormones for long periods of time. Work with your gynecologist for options to deal with the symptoms of menopause. ...Read more

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How do breast cancer anti estrogen pills work?

How do breast cancer anti estrogen pills work?

Starve tumor: Many tumors are fed by estrogen - the main female horomone. Anti-estrogen pills block the effects of estrogen (in a variety of different ways) and thereby starve the tumor from a vital growth factor. Even if you are postmenopausal (or even male) your body still produces estrogen in places like the adrenals and subcutaneous fat. ...Read more

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Should a 65-year old woman with a family history of breast cancer continue estrogen?

Should a 65-year old woman with a family history of breast cancer continue estrogen?

Probably not.: This can increase the risk for some breast cancers and endometrial cancer. Having a family history does not help. However, low dose hormone replacement therapy may be possible. It would be wise to see your doctor to be sure. ...Read more

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Dr. Barry Rosen
4,214 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


Receptor (Definition)

An organ, cell or molecule that accepts an outside signal and causes an internal change. Eyes receive light, touch receptors send messages to the brain when stimulated by pressure and estrogen receptors bind Estradiol causing responses of normal breast, ovary and uterus cells to rising and falling levels of the female steroid hormones. Most of the time "receptor" refers to one ...Read more