Doctor insights on:
Estrogen Progesterone Make Breast Cancer
If I have too much estrogen, or not enough progesterone, does that make me more susceptible to breast cancer?
Breast cancer risk: Maybe: some breast cancers take up estrogen as a sort of growth hormone to encourage growth, so too much estrogen can speed growth of these cancers. There is a very small increase in breast cancer risk with estrogen only given postmenopausally for the symptoms. Relative increase in Progesterone only is associated with some breast disorders also but cancer risk is unclear. ...Read moreSee 2 more doctor answers
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
I have breast cancer-Her 2 positive, progesterone & estrogen positive. On my health record it shows I have breast cancer (HCC). What does HCC mean?
Hormone replacement therapy. Estrogen alone increases risk of uterine cancer. Adding progesterone increases risk of breast cancer, but reduces risk of uterine cancer. What's the right balance?
Individual: Yes, estrogen alone does increase the risk of uterine cancer over time. And yes the whi showed that the combination of a certain synthetic estrogen and a certain synthetic progestin increased the risk of breast cancer. But most specialists do not use those older types of synthetic hormones and with newer medications the risks are lower and different. So a balance can be achieved. ...Read more
Are the risks of getting cancer (especially breast cancer) higher, if I am already on hormone treatment (estrogen and progestogen) at age 17?
Tamoxifen is given to breast cancer patients to suppress estrogen or both estrogen & progesterone?
Estrogen: Tamoxifen is given to individuals with specific breast cancers that are driven to grow by the presence of estrogen receptors. Tamoxifen interferes with the activity of estrogen in the breast, preventing cancer growth. The role of Progesterone receptors is unclear, though Progesterone receptors in breast cancer are generally associated with estrogen receptors, making tamoxifen an effective therapy. ...Read moreSee 2 more doctor answers
Starve tumor: Many tumors are fed by estrogen - the main female horomone. Anti-estrogen pills block the effects of estrogen (in a variety of different ways) and thereby starve the tumor from a vital growth factor. Even if you are postmenopausal (or even male) your body still produces estrogen in places like the adrenals and subcutaneous fat. ...Read moreSee 1 more doctor answer
No: There is no evidence Progesterone of any type prevents breast cancer, "natural" Progesterone or not. If a woman has menses that only occur a few times a year, six or four or fewer, however, Progesterone or progesterone-like compounds can very definitely prevent endometrial hyperplasia (which can lead to uterine cancer), and should be used regularly to oppose continuous estrogen stimulation. ...Read moreSee 2 more doctor answers
Feeds the cancer: Most breast cancers are estrogen receptor positive. The cancer cells have receptors that fit the estrogen molecule that a body produces. Think: a lock and key - when estrogen binds to the receptor the tumor cell is stimulated to grow and divide. Er+ tumors can be blocked by tamoxifen and Arimidex (anastrozole) (and others) that interfere with this pathway. ...Read moreSee 2 more doctor answers
How much estrogen gets into system using vaginal estrogen. Family history of breast cancer but not me. ?
Varies: Per the med insert: Premarin (conjugated estrogens) Vaginal Cream should not be used if you have unusual vaginal bleeding, have or had cancer, had a stroke or heart attack, have or had blood clots or liver problems, have a bleeding disorder, are allergic to any of its ingredients. This is due to significant absorption thru the vaginal mucosa which is dose dependent. Not the same risk for someone with family history only ...Read more
Im on estrogen pills how long should I take them before they run a risk of causing breast cancer and should they be took along?
5 yrs or less: It has been shown that using hormone replacement therapy (hrt) can increase one's risk of breast cancer when taken for longer than 5 years. Because of this we no longer recommend taking hormones for long periods of time. Work with your gynecologist for options to deal with the symptoms of menopause. ...Read moreSee 1 more doctor answer
Stimulates the growt: About 80% of breast cancer are er positive which means that the cancer cells are stimulated to grow by estrogen in the body. Decreasing the estrogen levels with tamoxifen which is an estrogen blocker in premenopausal women and aromatase inhibitors which stop estrogen production in sites other than the ovaries in post menopausal women is an important treatment. ...Read moreSee 1 more doctor answer
Anti-estrogen drugs: Anti-estrogen drugs are given to both premenopausal and postmenopausal women whose cancer is estrogen receptor-positive or progesterone receptor-positive. These cancer may grow when exposed to estrogen. Anti-estrogen medications block or reduce estrogen that is normally produced by the ovaries in premenopausal women or by fat cells, liver, adrenal glands or other organs in postmenopausal women. ...Read more
What can I do for hot flashes can't take estrogen due to breast cancer in family I lost my mom to cancer?
Occurs when glandular cells lining the milk ducts and lobules of the human breast begin to grow in an unregulated manner. Often curable if found early and treated effectively with surgery, hormonal therapy, chemotherapy and targeted therapy, or a combination thereof. Early detection before the malignancy becomes large enough to be felt depends on mammography/sonography and MRI imaging of the breast ...Read more
Most breast cancers are carcinomas. This is a type of breast cancer. These cancers start in the cells that line organs and tissues. In fact, breast cancers are often a type of carcinoma called adenocarcinoma, which starts in cells that make glands (glandular tissue). Breast adenocarcinomas start in the ducts (the milk ducts) or ...Read more
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