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Doctor insights on: Estrogen Hormone Replacement Therapy

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Still confused about estrogen, hormone replacement therapy and cardiovascular disease?

Still confused about estrogen, hormone replacement therapy and cardiovascular disease?

Complex issues: Female hormones increase thromboembolism, deep venous thrombosis--progesteron is blamed, more than estrogen--because at menopause, there is changes in blood coagulation?Increase weight, arteriosclerosis, metabolic syndrome all of this increase risk of cardiovascular disease-- estrogen can be given at low dose for brief periods. ...Read more

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Dr. Bryan Treacy
834 doctors shared insights

Hormone Replacement Therapy (Definition)

Usually done to provide the hormones that would be deficient upon surgical removal or inactivity or malfunction of a hormone producing gland or organ. The endocrinologist is the medical specialist that specializes amongst other things , in doing just that. Insulin/glucagon-pancreas, thyroid hormone-thyroid, ovaries, testicles, hypothalamus, ...Read more


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What are healthy blood levels of estrogen when on hormone replacement therapy?

What are healthy blood levels of estrogen when on hormone replacement therapy?

Invalid: There is no validity to following blood estrogen levels in order to adjust the dosage of hormone replacement. At age 32, I would not expect that you should need hormone replacement, unless you went through early menopause or had surgical removal of your ovaries. In postmenopausal women the dose is adjusted based on symptoms (hot flashes, sleep issues), not blood levels. ...Read more

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Why would my estrogen go down and testosterone go up while on MTF hormone replacement therapy?

Why would my estrogen go down and testosterone go up while on MTF hormone replacement therapy?

MTF: Does not make sense to me. I see MTF and FTM patients only after they have been evaluated and referred by a Psychologist and have yet to encounter this - not that I see that many, perhaps one or two a month. Something doesn't sound right so please have your doctor explain what is happening or have the doctor refer you to someone else. ...Read more

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Hormone replacement therapy. Estrogen alone increases risk of uterine cancer. Adding progesterone increases risk of breast cancer, but reduces risk of uterine cancer. What's the right balance?

Hormone replacement therapy. Estrogen alone increases risk of uterine cancer. Adding progesterone increases risk of breast cancer, but reduces risk of uterine cancer. What's the right balance?

Individual: Yes, estrogen alone does increase the risk of uterine cancer over time. And yes the whi showed that the combination of a certain synthetic estrogen and a certain synthetic progestin increased the risk of breast cancer. But most specialists do not use those older types of synthetic hormones and with newer medications the risks are lower and different. So a balance can be achieved. ...Read more

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Does hormone replacement therapy have significant risks?

Does hormone replacement therapy have significant risks?

It can: If not monitored. Estradiol and estriol levels are much higher in ovulating women & pregnant women, respectively. Birth control estrogen is 5x more potent than the estrogen used in hrt and carries risks of blood clots, heart attack etc. Estrone levels are high in overweight women who carry the same risks. Hrt that is not converted to estrone is the key, in my opinion. ...Read more

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How long do you need therapy for before starting hormone replacement therapy?

Please clarify: Hi. I'm not sure what you're referring to. We replace LOTS of hormones (thyroid, insulin, growth hormone, cortisol, aldosterone [given as fludrocortisone], estrogen, testosterone, progesterone, anti-diuretic hormone (given as DDAVP], etc, etc). I suspect you may be referring to archaic terminology for gonadal steroid replacement, but in that case, I have no idea what "therapy before starting" is ...Read more

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Does anyone have to be on hormone replacement therapy because of unbearable symptoms?

Does anyone have to be on hormone replacement therapy because of unbearable symptoms?

Yes: Hormone replacement therapy is used for things like unbearable symptoms. I assume we are talking about menopausal symptoms, but estrogen replacement can help with vaginal irritation, fatigue, hot flashes, etc. Talk to your doctor about it. ...Read more

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What's hormone replacement therapy (hrt) in 2012?

What's hormone replacement therapy (hrt) in 2012?

SAFE for most women: Hrt (and its reputation and safety) constantly changes as new studies come out. Here is the best 2012 review: in patients with no increased risk of breast cancer, heart disease, or blood clots, trans-dermal hrt (patch, cream, gel) is relatively safe, and safe for just a few years, but as few as necessary. An even better review: talk to your own doctor. ...Read more

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How safe was hormone replacement therapy? Will it come back?>

How safe was hormone replacement therapy? Will it come back?>

Bioidenticals: The women's health initiative study was terminated early for increase in breast cancer, heart attack ; stroke looked at only Premarin ; prempro which contain conjugated equine Estrogens ; progestin (synthetic; not progesterone). Studies show bioidentical hormones (hormones exactly like those you make) are safe for most people (men need HRT too). Progesterone ; estriol protect vs. Breast cancer. ...Read more

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Dr. Michael Kleerekoper
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Hormone (Definition)

A hormone (from greek ὁρμή, "impetus") is a chemical released by a cell or a gland in one part of the body that sends out messages that affect cells in other parts of the organism. Only a little amount of hormone is required to alter cell metabolism. In essence, it is a chemical messenger that transports a signal from ...Read more


Estrogen (Definition)

Estrogen is a hormone that is secreted by the ovaries and affects ovulation, ...Read more