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Doctor insights on: Estrogen Based Breast Cancer

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Is dcis breast cancer genetic?

Is dcis breast cancer genetic?

It can be: Dcis, the earliest form of breast cancer, can be associated with brca mutations. 13% of women under 50 diagnosed with dcis had a brca mutation in retrospective (looking backwards) studies. Women with a family history of breast or ovarian cancer or dcis before age 50 should have genetic counseling. For more info: http://clincancerres.Aacrjournals.Org/content/13/14/4306.Full. ...Read more

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Dr. Barry Rosen
4,450 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Do the breast enhancement pills "breast actives" cause breast cancer or uterus cancer?

Do the breast enhancement pills "breast actives" cause breast cancer or uterus cancer?

Unknown: Breast enhancement pills are not regulated and therefore may have various unknown substances in them. Some of those substances, especially if they include estrogen, may increase risk of cancers. ...Read more

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What is estrogen receptor positive breast cancer?

What is estrogen receptor positive breast cancer?

One with receptors.: These are tumors with estrogen receptors on them. This makes them susceptable to some chemotherapeutic agents, like tamoxifen. ...Read more

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Male breast cancer and testosterone supplementation?

Male breast cancer and testosterone supplementation?

What is the question: Asking if testosterone causes male breast cancer or increases its risk? Asking if testosterone should be taken by a man with breast cancer? Should not take hormone supplements if one has male breast cancer without conferring with your oncologist first. ...Read more

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Relation between phytoestrogens based cream for breast firming and breast cancer?

Relation between phytoestrogens based cream for breast firming and breast cancer?

Estrogens are double: Edged. You do not state age or menopausal status. All estrogens, phyto, endogenous or pharmacy have risk. So weigh if it is worth it. I'd vote no. ...Read more

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My mom had lobular breast cancer at 52. Brca negative. Is lobular breast cancer more genetic based than ductal?

My mom had lobular breast cancer at 52. Brca negative. Is lobular breast cancer more genetic based than ductal?

No its medullary: a quote from Lancethttp://www.ncbi.nlm.nih.gov/pubmed/9167459: "The occurrence of invasive lobular carcinoma and invasive ductal carcinoma was not significantly different between carriers of BRCA1 or BRCA2 mutations and controls. Medullary or atypical medullary carcinoma was, however, found more often in BRCA1 (13%, p ...Read more

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Are breast cancer and colon cancer linked?

Are breast cancer and colon cancer linked?

Not directly usually: There is debate about how closely these 2 cancers are related. Both have hereditary natures and are more common generally in obese patients. Both often begin with more benign precursor lesions like dcis for breast cancer and benign polyps for colon cancer. Both are very common but there is little evidence that having either predisposes to having the other. ...Read more

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Describe breast cancer staging according tnm?

Describe breast cancer staging according tnm?

Tumor,Nodes,Mets: The t, n, m system classifies breast cancers based upon tumor size(t), lymph node status(n), and presence of cancer elsewhere in the body(m). Stage i is limited to small cancers +/- microscopic ln disease. Stage ii describes tumors 2-5cm +/- ln disease. Stage iii is for more advanced tumors (>5cm, skin/chest wall involvement) +/- multiple/distant ln. Stage IV describes metastatic disease. ...Read more

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Tamoxifen is given to breast cancer patients to suppress estrogen or both estrogen & progesterone?

Tamoxifen is given to breast cancer patients to suppress estrogen or both estrogen & progesterone?

Estrogen: Tamoxifen is given to individuals with specific breast cancers that are driven to grow by the presence of estrogen receptors. Tamoxifen interferes with the activity of estrogen in the breast, preventing cancer growth. The role of Progesterone receptors is unclear, though Progesterone receptors in breast cancer are generally associated with estrogen receptors, making tamoxifen an effective therapy. ...Read more

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Does estradi case breast cancer?

Does estradi case breast cancer?

Possibly: Estrogen receptor type of cancer incidence fell after scientific studies linking estrogen use with increased risk of breast cancer caused many women to discontinue their use, but other studies gave less convincing conclusions. ...Read more

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Do fibrocystic breast changes increase my risk of breast cancer?

Do fibrocystic breast changes increase my risk of breast cancer?

No, fibrocystic breast changes don't increase your risk of breast cancer: Fibrocystic breast changes are common. Women with this noncancerous (benign) condition often have lumpy, nodular breasts and experience breast pain that varies throughout the menstrual cycle. Doctors don't know exactly what causes fibrocystic breast changes, but the condition is likely due to hormone changes during your menstrual cycle that affect breast tissue. Although fibrocystic breast changes don't increase your risk of breast cancer, having fibrocystic breasts may make it more difficult for you to feel a new breast lump or other abnormal change — such as a persistent breast lump that doesn't go away with your next menstrual cycle or thickening or firmness within lumpy breast tissue. It's important to become familiar with how your breasts normally feel so that you'll know when something just isn't right. If you detect something unusual, make an appointment with your doctor to have it evaluated. ...Read more

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Correlation between breast cancer and ovarian cancer?

Correlation between breast cancer and ovarian cancer?

SMALL: In 90% of cases there is no correlation. In 10% of cases it may be associated with the hereditary breast ovarian syndrome in which brca 1 & brca 2 mutations are responsable for the increase risk and development of these cancers. ...Read more

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Hormonal effects of chemotherapy for breast cancer?

Hormonal effects of chemotherapy for breast cancer?

Please clarify.: It is unclear from your question what you are asking. Most breast cancers are estrogen-sensitive and can be treated with anti-estrogen medication (tamoxifen, aromatase inhibitors). Many women who are peri menopausal when receiving traditional chemotherapy develop ovarian suppression from the chemo and effectively "go into" menopause. I hope this helps. ...Read more

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Hormone replacement therapy. Estrogen alone increases risk of uterine cancer. Adding progesterone increases risk of breast cancer, but reduces risk of uterine cancer. What's the right balance?

Hormone replacement therapy. Estrogen alone increases risk of uterine cancer. Adding progesterone increases risk of breast cancer, but reduces risk of uterine cancer. What's the right balance?

Individual: Yes, estrogen alone does increase the risk of uterine cancer over time. And yes the whi showed that the combination of a certain synthetic estrogen and a certain synthetic progestin increased the risk of breast cancer. But most specialists do not use those older types of synthetic hormones and with newer medications the risks are lower and different. So a balance can be achieved. ...Read more

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Can ovarian cancer and breast cancer be hereditary?

Can ovarian cancer and breast cancer be hereditary?

Yes, of course: This is one of the classic hereditary cancer syndromes. Sorry, i don't have enough characters to be allowed to give you a full asnwer here, but quoting wikipedia: http://en.Wikipedia.Org/wiki/hereditary_breast%e2%80%93ovarian_cancer_syndrome. ...Read more

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Is breast density a risk factor for breast cancer? Mammogram noted "extremely dense breasts".

Yes, breast density: is a risk factor for breast cancer. The relative risk for extremely dense breasts is about 4x the relative risk of patients with almost entirely fatty breasts, and about 1.6x the RR for "average" density breasts. Find out all you need to know at http://www.breastdensity.info/ ...Read more

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Benign breast disease and the risk of breast cancer?

Benign breast disease and the risk of breast cancer?

Depends: Most benign breast findings do not lead to or cause breast cancer. Some breast tissue biopsies can show benign but possibly pre-cancerous cells, such as atypical ductal hyperplasia or lobular neoplasia (for example). You would need to discuss any breast biopsy results and their possible risks with your doctor. ...Read more

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Can thyroid cancer increase breast cancer risk?

Can thyroid cancer increase breast cancer risk?

Not usually: There are some families who have increased rates of a variety of cancers, including papillary thyroid cancer, breast cancer, and colon cancer. But having one does not cause an risk for another; instead inherited genes put a person at increased risk for both. A person with a history of thyroid cancer should be sure to get recommended mammograms and colon tests. ...Read more

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Could premerin homone replacement cause Paget breast cancer?

Could premerin homone replacement cause Paget breast cancer?

Unlikely: We think that combined hormone replacement including estrogen and Progesterone cause an increase in breast cancer of which paget's disease if the breast is a type. Premarin (conjugated estrogens) only contains estrogen. ...Read more

Dr. Mark Hoepfner
1,072 doctors shared insights

Breast Carcinoma (Definition)

Most breast cancers are carcinomas. This is a type of breast cancer. These cancers start in the cells that line organs and tissues. In fact, breast cancers are often a type of carcinoma called adenocarcinoma, which starts in cells that make glands (glandular tissue). Breast adenocarcinomas start in the ducts (the milk ducts) or ...Read more


Estrogen (Definition)

Estrogen is a hormone that is secreted by the ovaries and affects ovulation, ...Read more