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Doctor insights on: Estrogen And Breast Cancer Risk

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Had hyster at 32, ovaries removed. On estradiol 1 mg daily for HRT. Told its needed and safe. No breast cancer risk for estrogen only!? Is this true?

Had hyster at 32, ovaries removed. On estradiol 1 mg daily for HRT. Told its needed and safe. No breast cancer risk for estrogen only!? Is this true?

No breast Ca risk: Question is raised as to rationale of total hysterectomy at 32. Hormone therapy is indicated but has no relationship to the induction of breast Cancer. There latter is induced in most patients by viral transformation thru the Wnt gene and not ingestion of hormones. Fire is not caused by spilling gasoline on paper. The paper must be on fire and Ca must be present in breast for stimulation. ...Read more

Dr. Barry Rosen
4,464 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Total hysterectomy at 32 for bilateral dermoid cysts. On estradiol HRT. Told its safe and no breast cancer risk with estrogen only? Is this true?

Total hysterectomy at 32 for bilateral dermoid cysts. On estradiol HRT. Told its safe and no breast cancer risk with estrogen only? Is this true?

I would agree: Your surgeon ie breast surgeon ,if you had one may not agree.I would say that at this point in your life the benefits outweigh the risks,especially if you don't have a breAst cancer history in your family.The problem with having surgical menopause at such a young age , is genitourinary atrophy and bone loss.It also affects libido ...Read more

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I had a healthy shake that had soy lecithin in it will that cause high estrogen and breast cancer I'm worried?

I had a healthy shake that had soy lecithin in it will that cause high estrogen and breast cancer I'm worried?

A Shake: One shake is not going to alter your risk for anything. Soy lecithin is not a harmful substance anyway and is not a risk factor for breast cancer or any other disease. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. Get HPV vaccine. ...Read more

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What is the role of estrogen in breast cancer?

What is the role of estrogen in breast cancer?

Stimulates the growt: About 80% of breast cancer are er positive which means that the cancer cells are stimulated to grow by estrogen in the body. Decreasing the estrogen levels with tamoxifen which is an estrogen blocker in premenopausal women and aromatase inhibitors which stop estrogen production in sites other than the ovaries in post menopausal women is an important treatment. ...Read more

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If I had breast cancer, can I take estrogen in menopause?

If I had breast cancer, can I take estrogen in menopause?

Probably not: You should speak with your oncologist, however, Estrogens are usually not recommended if you have had breast cancer. ...Read more

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Do high estrogen levels cause breast cancer in men?

Do high estrogen levels cause breast cancer in men?

IT'S A RISK FACTOR: Prolonged exposure to estrogen is a risk factor for breast cancer in men. Obesity, liver cirrhosis and high alcohol intake can lead to a high estrogen state. ...Read more

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Is it true that estrogen increases the risk of breast cancer?

Is it true that estrogen increases the risk of breast cancer?

HRT-yes: The use of hormone replacement therapy (hrt) for menopause has been shown to increase the risk for breast cancer when used longer than 5 years. Oral contraceptives do not have any relation nor increase in risk of breast cancer. ...Read more

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If my breast cancer feed off estrogen bein a female how can I reduce it in my body?

If my breast cancer feed off estrogen bein a female how can I reduce it in my body?

Anti-hormone drugs: If you have been diagnosed with hormone-receptor positive breast cancer, you should be on a medication to either block estrogen (tamoxifen) or, if you are post-menopausal, to decrease the level of estrogen in your body (letrozole, anastrazole, or exemestane). You can lose weight if you are obese, which will also decrease the estrogen in your body. However, anti-estrogen drugs are very important! ...Read more

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How long would I have to take estrogen before I start worrying bout breast cancer.?

How long would I have to take estrogen before I start worrying bout breast cancer.?

5 yrs or less: It has been shown that using hormone replacement therapy (hrt) can increase one's risk of breast cancer when taken for longer than 5 years. Because of this we no longer recommend taking hormones for long periods of time. Work with your gynecologist for options to deal with the symptoms of menopause. ...Read more

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How do breast cancer anti estrogen pills work?

How do breast cancer anti estrogen pills work?

Starve tumor: Many tumors are fed by estrogen - the main female horomone. Anti-estrogen pills block the effects of estrogen (in a variety of different ways) and thereby starve the tumor from a vital growth factor. Even if you are postmenopausal (or even male) your body still produces estrogen in places like the adrenals and subcutaneous fat. ...Read more

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What is estrogen receptor positive breast cancer?

What is estrogen receptor positive breast cancer?

One with receptors.: These are tumors with estrogen receptors on them. This makes them susceptable to some chemotherapeutic agents, like tamoxifen. ...Read more

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What is meant by having estrogen receptor positive breast cancer?

What is meant by having estrogen receptor positive breast cancer?

Feeds the cancer: Most breast cancers are estrogen receptor positive. The cancer cells have receptors that fit the estrogen molecule that a body produces. Think: a lock and key - when estrogen binds to the receptor the tumor cell is stimulated to grow and divide. Er+ tumors can be blocked by tamoxifen and Arimidex (anastrozole) (and others) that interfere with this pathway. ...Read more

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Should a 65-year old woman with a family history of breast cancer continue estrogen?

Should a 65-year old woman with a family history of breast cancer continue estrogen?

Probably not.: This can increase the risk for some breast cancers and endometrial cancer. Having a family history does not help. However, low dose hormone replacement therapy may be possible. It would be wise to see your doctor to be sure. ...Read more

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If I have too much estrogen, or not enough progesterone, does that make me more susceptible to breast cancer?

If I have too much estrogen, or not enough progesterone, does that make me more susceptible to breast cancer?

Breast cancer risk: Maybe: some breast cancers take up estrogen as a sort of growth hormone to encourage growth, so too much estrogen can speed growth of these cancers. There is a very small increase in breast cancer risk with estrogen only given postmenopausally for the symptoms. Relative increase in Progesterone only is associated with some breast disorders also but cancer risk is unclear. ...Read more

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Im on estrogen pills how long should I take them before they run a risk of causing breast cancer and should they be took along?

Im on estrogen pills how long should I take them before they run a risk of causing breast cancer and should they be took along?

5 yrs or less: It has been shown that using hormone replacement therapy (hrt) can increase one's risk of breast cancer when taken for longer than 5 years. Because of this we no longer recommend taking hormones for long periods of time. Work with your gynecologist for options to deal with the symptoms of menopause. ...Read more

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How much estrogen gets into system using vaginal estrogen. Family history of breast cancer but not me. ?

How much estrogen gets into system using vaginal estrogen. Family history of breast cancer but not me. ?

Varies: Per the med insert: Premarin (conjugated estrogens) Vaginal Cream should not be used if you have unusual vaginal bleeding, have or had cancer, had a stroke or heart attack, have or had blood clots or liver problems, have a bleeding disorder, are allergic to any of its ingredients. This is due to significant absorption thru the vaginal mucosa which is dose dependent. Not the same risk for someone with family history only ...Read more

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What can I do for hot flashes can't take estrogen due to breast cancer in family I lost my mom to cancer?

What can I do for hot flashes can't take estrogen due to breast cancer in family I lost my mom to cancer?

SSRI;s: Selective Serotonin Reuptake Inhibitors (SSRI's) commonly known as a class of anti-depressants can be effective in minimizing hot flashes. Talk to your GYN MD about this and any other alternatives to estrogen Rx's that may be available. ...Read more

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Hormone replacement therapy. Estrogen alone increases risk of uterine cancer. Adding progesterone increases risk of breast cancer, but reduces risk of uterine cancer. What's the right balance?

Hormone replacement therapy. Estrogen alone increases risk of uterine cancer. Adding progesterone increases risk of breast cancer, but reduces risk of uterine cancer. What's the right balance?

Individual: Yes, estrogen alone does increase the risk of uterine cancer over time. And yes the whi showed that the combination of a certain synthetic estrogen and a certain synthetic progestin increased the risk of breast cancer. But most specialists do not use those older types of synthetic hormones and with newer medications the risks are lower and different. So a balance can be achieved. ...Read more

Dr. James Dukelow
11 doctors shared insights

Thalassemia And Hemoglobinopathy (Definition)

Thalassemia is a type of hemoglobinopathy. It is inherited from one or both of your parents. There are many kind of thalassemia. Most causes anemia (low red blood cell count). Anemia couod be severe requiring blood. Taking iron does not cure the disease. Thalassemia is common in people living in the mediteranian countries, africa, middle east, india, and sotheastern asia such ...Read more


Dr. Hunter Handsfield
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Hsv Type 1 And 2 (Definition)

A variety of infections caused by herpes simplex virus types 1 and 2. Type 1 infections are marked by the eruption of vesicles on lips or at the external nares; type 2 by such lesions on the genitalia. Both types often are dormant and reappear during febrile illnesses or even physiologic states such as menstruation. The viruses become latent and and may not ...Read more