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Doctor insights on:
Estrace Estrogen Based Agent
1
Outside of compounded estrogens, is estrasorb the only topical estrogen for hormone regulation, not vaginal issues. ?

No: There are various patches. Vivelle (estradiol) is the most commonly used. I like vivelle (estradiol) because it comes in various doses that allows for very selective titration of dose. ...Read more
Estradiol Level (Definition)
Estradiol is the main estrogen produced by the ovary. The level is a laboratory measurement of estradiol. This level will fluctuate during a menstrual cycle and ...Read more
2
What is Premarin (conjugated estrogens) vaginal cream used for?

FOR VAGINAL DRYNESS: It is used for vaginal dryness during menopause, especially if it also causes painful intercourse it is also sometime used in pediatric practice for labial adhesions. ...Read more
3
When adding estrogen to prometrium (micronized progesterone) for perimenopausal relief how is amt. Determined?

Starting dose: Most people will use 1-2 mg which are the lowest doses for effectiveness, sometime we go higher if symptoms are persistant. ...Read more
4
Which synthetic estrogen is safest, Estradiol Valerate, Mestranol, or Ethinyl Estradiol?

Synthetic meds: 1st no such thing as free lunch ie there's always some potential risk or side effect. 2nd FDA only approves meds which they deem benefit greater than risk (tho obviously not w/o disagreement & controversy). 3rd no studies demonstrate benefit of any oral estrogen over another tho some studies suggest topical safe than oral. 4th Natural isn't safe than synthetic ie tobacco is natural but isn't safe! ...Read more
5
Which costs less: conjugated estrogens (premarin) or the bio-identical estrogen patch?

Varies: The prices for either can vary widely between different pharmacies. The least expensive form of estrogen replacement therapy is usually generic ethynil Estradiol which is available for as little as $4 for a one month supply at some pharmacies. ...Read more
6
Which is better: crinone (progesterone gel) or standard progesterone suppositories?

Crinone (progesterone gel).: Crinone (progesterone gel) is a more absorbable formulation of vaginal Progesterone and approved to prevent preterm birth in women with very short cervix (<15-20 mm) by transvaginal prenatal ultrasound. Suppositories are not approved for that indication! use Crinone (progesterone gel) 8% (90 mg per 1.125g) nightly until 37 weeks if your physician agrees. ...Read more
7
Does serm and synthethic estrogens metabolized as natural estrogen?

Yes: Typically, these are all metabolized the samer. ...Read more
8
Can natural progesterone cream offset the negative effects of synthetic progestin (legonorgestrel)?

no: No. They are both progestins. The cream will work locally but do the same thing. ...Read more
9
Which dose is stronger...10mcg or 0.1mg? I am comparing vagifem and estrace (estradiol) cream

1000 : 1000 mcg make up 1 mg so 100 mcg = 0.1 mg 10 mcg = 0.01 mg 1 mcg = 0.001 so, the 0.1 mg dose is 10 times stronger than the 10 mcg dose. I hope this helps!. ...Read more
10
Which brand of natural progesterone cream is advisable to use for treating pcos & estrogen dominance?

None: Skin Progesterone creams are not fda regulated and absorption rates are unknown - would not use these for anything ...Read more
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11
Is estratest (esterified estrogens and methylestosterone) a biochemical hormone?

Yes...: ...But perhaps you mean bioidentical. All hormones are biochemicals. Estratest (esterified estrogens and methylestosterone) is a combination of methyltestosteone, which is synthetic and not the same as your own testosterone, and mixed estrogen hormones which are excreted by pregnant mares in their urine. These hormones are similar to, but not identical to, natural human hormones. ...Read more
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12
Is 0.625g of Premarin (conjugated estrogens) a lot?

Very standard: Dose.
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13
Does vagifem replace Premarin (conjugated estrogens) & provera?
No: Vagifem treats the vagina locally for atrophic vaginitis. Premarin (conjugated estrogens) and Provera are systemic hormones used for hot flashes. ...Read more
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14
Tamoxifen is given to breast cancer patients to suppress estrogen or both estrogen & progesterone?

Estrogen: Tamoxifen is given to individuals with specific breast cancers that are driven to grow by the presence of estrogen receptors. Tamoxifen interferes with the activity of estrogen in the breast, preventing cancer growth. The role of Progesterone receptors is unclear, though Progesterone receptors in breast cancer are generally associated with estrogen receptors, making tamoxifen an effective therapy. ...Read more
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15
Is the prometrium (micronized progesterone) a bio identical hormone?

Prometrium (micronized progesterone): Yes. Prometrium (micronized progesterone) is natural Progesterone and is a bio identical hormone to human progesterone. ...Read more
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16
If I'm transsexual, will 1.25 mg of Premarin (conjugated estrogens) be effective?

Sorry that your: question has not been addressed yet. I'm not expert in the area you want addressed but encourage you to speak with a doctor who is. That will give you the best answer. Peace and good health. ...Read more
17
When prometrium (micronized progesterone) stimulates instead of sedates a perimenopausal woman what should be taken? Estrogen in combo with prometrium (micronized progesterone)?

Go see your doctor: While our impression of estrogen for perimenopausal women has changed dramatically over the last decade, it still should be used for right reason, and sedation is not one of them. So go see your prescribing doctor & tell her/him about your side effects so that s/he can offer you some alternatives (rather than just throw more medications at you). ...Read more
18
Where is information on normal levels of progesterone, estradiol, estriol, testosterone & dhea?

Lab reference ranges: Levels of these hormones are only as reliable as their test kits. One lab may use a different method for detection than another. You may not be able to compare values between different labs. Labs also set their normal ranges based on multiple tests. You need to discuss these hormones with an endocrinologist as they're trained to understand the different testing methods. ...Read more
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19
Hormone replacement- is the dose and duration of prometrium (micronized progesterone) used in menopause dependent on the dose of estrogen being used by the patient.?

Not necessarily: If you still have a uterus, then you need a combination of estrogen and progesterone. The Progesterone can by taken continuously or in a cyclic fashion. Remember, you are only using the minimum dose of hormones to treat the symptoms that are bothering you. Discuss these doses with your doctor. ...Read more
20
Is postmenopausal bladder prolapse progress slowly? Only using estrace cream for HRT.

Bladder prolapse: Although Estrace cream can assist in keeping the epithelium of the vagina distensible, post menopausal bladder prolapse is more function of the lack of bladder ligament support or prior vaginal childbirth trauma. Patient's who have had multiple vaginal deliveries are more likely to see a more rapid bladder prolapse then not. ...Read more
Estrogen (Definition)
Estrogen is a hormone that is secreted by the ovaries and affects ovulation, ...Read more
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