Doctor insights on:
Essential Thrombocythemia Eczema Lupus
A range of persistent skin conditions that include dryness and recurring skin rashes that are characterized by one or more of these symptoms: redness, skin edema (swelling), itching, crusting, flaking, blistering, cracking, or bleeding. The cause of eczema is unknown but is presumed to be a combination of ...Read more
I have had essential thrombocythemia but suddenly my platelets have dropped low. What could this be?
Many issues: You should see your doctor. Some issues are better discussed in person. ...Read more
By definition: All overgrowths of blood cells and the elements that form them are by definition cancer, since blood cells by their nature travel through the body. Given this, "ET" isn't even a life-shortener on the average, and I hope your illness proves manageable if it needs to be managed at all. ...Read more
By definition: Since the cells of the blood invade tissue, all tumors / clonal overgrowths are by definition cancers. Essential thrombocythemia can usually be kept at bay easily for decades. ...Read more
In the past year my ferritin has gone from 40 to 28. I am 42. No periods. Should i be concerned about this? I also have essential thrombocythemia
See your doctor: You need to be thoroughly evaluated by your doctor to see what's going on. ...Read more
Quite common: For the whole population, maybe 1 person in 2000. It's more common in older folks, less so in youngsters. ...Read more
Yes-5% risk: Essential thrombocythemia is part of myeloprolifeartive neoplasm umbrealla where in et the bone marrow for some uknown reason-proliferate too much platelet- that can go up above a million. They are abnormal and sticky platelet. Due to the abnormal level and function of platelet, there would be risk for blood clots as well as bleeding. The risk of et to develop into acute leukemia is about 5 %. ...Read moreSee 1 more doctor answer
Neoplasm: Essential thrombocythemia (et) is part of group of myeloproliferative neoplasm (mpn) - is a clonal disorder. Mpns are predisposed to clonal evolution and disease transformation to myelodysplasia and/or acute leukemia. The propensity to transform into acute myeloid leukemia differs among the subgroups- being the highest for cml- greater than 90% if left untreated and et being the least - about 5%. ...Read more
Platelets: Need more information like what is your platelts count and any symptoms. No symptom-no treatment. Since you have diagnosis of essential thrombocythemia and tested positive for philadelphia chromosome mean you have hematologist who has ruled out other causes of thrombocythemia and any lymphocytic leukemia connection. Please stay in touch with hematologist. Wish you best of health. ...Read more
ET: Hydroxyurea, anagrelide, and alpha-interferon are conventional therapies for essential thrombocythemia. Pipobroman is widely used in europe, but not available in the United States. Low-dose Aspirin is possibly effective in preventing thrombosis (clot formation) in et. Low-dose asa is especially effective in managing the vasomotor symptoms of et. ...Read more
Too many platelets: The myeloproliferative neoplasms (mpns) involve terminal myeloid cell expansion in the peripheral blood, resulting in various combinations of erythrocytosis (rbc's), leukocytosis (wbc's), thrombocytosis (platelets), bone marrow hypercellularity/fibrosis, and splenomegaly (enlarged spleen). Essential thrombocythemia is a diagnosis of exclusion, made when other forms of mpn are ruled out. ...Read more
Too many platelets: Myeloproliferative disorders are a set of marrow malignancies characterized by excessive production of certain types of blood cells. Essential thrombocytopenia is one of them, in which marrow makes too many platelets. There are well-tolerated oral agents which help. Other myelodysplastic syndromes are polycythemia vera and chronic myelogenous leukemia. ...Read more
See below: Polycythemia vera (PV) is characterized by uncontrolled production of red blood cells along with specific JAK2 gene mutation and decreased epo level. Essential thrombocythemia (ET) comes with uncontrolled elevation in platelet count. JAK2 mutation occurs only in 50% of ET. Bone marrow biopsy may be required for the diagnosis of ET. Both are clonal myeloproliferative neoplasms. ...Read more
May be: It is a mild form of leukemia and may not cause symptoms. Some patients do develop complications. There is no cure through conventional treatments. In some cases bone marrow transplant may be warranted and can cure the disease. See this site for more info. http://www.mayoclinic.org/diseases-conditions/thrombocythemia/basics/definition/con-20034386 ...Read more
Please let me know if there is any alternate treatment for essential thrombocythemia or high platelets?
Always alternatives: There are alternative treatments for everything. However, the question is whether any are effective for ET. None are yet proven but a healthy diet, detoxification, exercise, herbs like turmeric, Japanese Knotweed & medical marijuana, stress reduction, homeopathy and acupuncture are worth exploring. See http://medicalmarijuana.com/medical-marijuana-treatments/E-T- Work with an integrative doctor. ...Read more
My mom is 78 and was diagnosed w/essential thrombocythemia and is treatable with pills.is this a form of cancer?I also here it as a disease.
Manageable cancer: ET, as it also called, is a disease with mutations in bone marrow cells leading to overproduction of platelets, packed bone marrow with abnormal platelet-producing cells, called megakaryocytes. The diagnosis is aided by testing for this mutation. Pills such as hydrea (hydroxyurea) and anagrelide control this overproduction. The disease is somewhat slow growing but can lead to leukemia and need hematology care. ...Read more
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