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Doctor insights on: Essential Thrombocythemia Eczema Lupus

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I have essential thrombocythemia. Is this a life long disease?

Yes : Treatment of essential thrombocythemia depends on your risk of blood-clotting or bleeding episodes. If you're younger than 60, have had no signs or symptoms, and have no other risk factors for developing blood clots, such as smoking, you may simply need periodic medical checkups. ...Read more

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What does myeloproliferative disorder with essential thrombocythemia mean?

What does  myeloproliferative disorder with essential thrombocythemia mean?

Too many platelets: The myeloproliferative neoplasms (mpns) involve terminal myeloid cell expansion in the peripheral blood, resulting in various combinations of erythrocytosis (rbc's), leukocytosis (wbc's), thrombocytosis (platelets), bone marrow hypercellularity/fibrosis, and splenomegaly (enlarged spleen). Essential thrombocythemia is a diagnosis of exclusion, made when other forms of mpn are ruled out. ...Read more

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What is a myeloproliferative disorder that includes essential thrombocythemia?

What is a myeloproliferative disorder that includes essential thrombocythemia?

Too many platelets: Myeloproliferative disorders are a set of marrow malignancies characterized by excessive production of certain types of blood cells. Essential thrombocytopenia is one of them, in which marrow makes too many platelets. There are well-tolerated oral agents which help. Other myelodysplastic syndromes are polycythemia vera and chronic myelogenous leukemia. ...Read more

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What is the difference between polycythemia vera and Essential thrombocythemia?

What is the difference between polycythemia vera and Essential thrombocythemia?

See below: Polycythemia vera (PV) is characterized by uncontrolled production of red blood cells along with specific JAK2 gene mutation and decreased epo level. Essential thrombocythemia (ET) comes with uncontrolled elevation in platelet count. JAK2 mutation occurs only in 50% of ET. Bone marrow biopsy may be required for the diagnosis of ET. Both are clonal myeloproliferative neoplasms. ...Read more

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How many people have essential thrombocythemia (ET)?

Quite common: For the whole population, maybe 1 person in 2000. It's more common in older folks, less so in youngsters. ...Read more

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Is there a connection betwen essential thrombocythemia and leukemia?

Is there a connection betwen essential thrombocythemia and leukemia?

Yes-5% risk: Essential thrombocythemia is part of myeloprolifeartive neoplasm umbrealla where in et the bone marrow for some uknown reason-proliferate too much platelet- that can go up above a million. They are abnormal and sticky platelet. Due to the abnormal level and function of platelet, there would be risk for blood clots as well as bleeding. The risk of et to develop into acute leukemia is about 5 %. ...Read more

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Is essential thrombocythemia a form of cancer?

Is essential thrombocythemia a form of cancer?

Neoplasm: Essential thrombocythemia (et) is part of group of myeloproliferative neoplasm (mpn) - is a clonal disorder. Mpns are predisposed to clonal evolution and disease transformation to myelodysplasia and/or acute leukemia. The propensity to transform into acute myeloid leukemia differs among the subgroups- being the highest for cml- greater than 90% if left untreated and et being the least - about 5%. ...Read more

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What are the treatment for essential thrombocythemia?

What are the  treatment for essential thrombocythemia?

ET treatment: A drug called hydroxy-urea will be the treatment to reduce platelet levels. Then on the high risk group, Aspirin will be needed too. Discuss in detail with your hematologist. ...Read more