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Doctor insights on: Esophageal Squamous Cell Carcinoma

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Is metastatic squamous cell carcinoma genetic?

Is metastatic squamous cell carcinoma genetic?

Genetic component?: There could be genetic component to a squamous cell cancer, although the exact implications on treatment aren't known. Obviously if there is a strong family history of cancers, or if it strikes someone who is young and/or a non smoker/drinker i would suspect a strong genetic contribution. Without more details, it is hard to say with any certainty. ...Read more

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Dr. Barry Rosen
4,348 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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What are squamous cell carcinoma, basal cell carcinoma, and melanoma?

What are squamous cell carcinoma, basal cell carcinoma, and melanoma?

Types of cancer: Malignant melanoma is a type of cancer that originates from the melanocytes. It often travels to distant locations in the body and is the deadliest form of skin cancer. Basal cell carcinoma rarely travels to other parts of the body, but will recur locally if not treated appropriately. Squamous cell carcinoma rarely travels to other parts of the body. ...Read more

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Invasive non keratinizing squamous cell carcinoma tongue showing nests of malignant squamous cells grade 3 prognosis?

Invasive non keratinizing squamous cell carcinoma tongue showing nests of malignant squamous cells grade 3 prognosis?

Can be cured: If no nodes palpable and lesion localized, RT chemo can reduce size and position site for curative resection. Partial glossectomy after initial therapy. If larger and not responsive to chemo, Ive used hight dose MTX with citrovorum factor over 12 hrs. Most effective in presence of nodal disease Basic chemo is Platinum/Taxol + RT ...Read more

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Is squamous cell carcinoma keratoacanthoma variant deadly?

Is squamous cell carcinoma keratoacanthoma variant deadly?

Not really: Not necessarily. It could appear suddenly and grow rapidly. But then it will reach a certain size then it will stop growing, and then regress weeks to months later. As long as it is contained, localized in the skin- surgical resection will take care of that . However if it has metastasized ( which is not common ) -then it will give you problem. ...Read more

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Non-small cell carcinoma vs small cell carcinoma?

Non-small cell carcinoma vs small cell carcinoma?

Small cell was: Distinguised because there is almost never a role for surgery, and always a role for chemotherapy. Non-small cell prior to 1980 never had chemotherapy. Both are caused by smoking sclc 100%; /nsclc 90-95%. Nsclc just in lung usually treated with surgery. Any + node gets chemo. If mediastinal nodes are positive, standard is chemo/xrt. Get more than 1 opinion before starting treatment if yo have ? ...Read more

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Is infiltrative basal cell carcinoma an aggressive cancer?

Is infiltrative basal cell carcinoma an aggressive cancer?

Can Be: Usually basal cell carcinoma tend to be less aggressive than some other types of skin cancers. Here is a good resource for more on the topic http://www.Cancer.Net/cancer-types/skin-cancer-non-melanoma. ...Read more

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What characterizes early stage squamous cell carcinoma?

What characterizes early stage squamous cell carcinoma?

Nothing: Even in the lung, squamous cell carcinomas are usually silent until they have become large enough to cause coughing up of blood -- one of the common ways in which it announces itself. On the skin, of course, a growing mass with a rough surface is (depending on how it looks) likely to be a squamous skin cancer; these are usually easy to cure. Good luck. ...Read more

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What exactly is squamous cell carcinoma lung cancer?

What exactly is squamous cell carcinoma lung cancer?

One type of cancer: There are a number of variants of lung cancer and these are named for their microscopic appearance, the main ones being: squamous cell, adenocarcinoma, small cell carcinoma and large cell carcinoma. In squamous cell cancer, the tumor cells resemble skin cells. This type of tumor is commonly seen in smokers. ...Read more

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Does invasive squamous cell carcinoma spread quickly?

Does invasive squamous cell carcinoma spread quickly?

Depends: Origin of cancer is very important. If skin, usually not unless large, ulcerated lesion. Depending on site, stage at presentation then plays a role. Squamous cancers can origin wherever there is skin lining with then resultant pattern of spread so tough to say more. ...Read more

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What is vasive squamous cell carcinoma?

What is vasive squamous cell carcinoma?

"Invasive" - deeper: Skin squamous cell carcinoma (scc) often goes through stages of evolution on its way to becoming "invasive" and eventually metastasizing. It may begin as an area of sun damage or pre-cancer (actinic keratosis) and worsen to become a superficial scc that does not yet invade deeper (scc in situ). Eventually, the scc will start to go deeper and become "invasive", then metastasize if left unchecked. ...Read more

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Is squamos cell carcinoma of tonsils cureable?

Is squamos cell carcinoma of tonsils cureable?

Yes: It may be curable but you will need and extensive work up and close follow up with your otolaryngology surgeon (ent). Depending on the extent of cancer treatment may consist of any combination of surgery, radiation, and chemotherapy. Maintaining your nutrition and mental health during this time would be very important as well. ...Read more

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What is squamous cell vs basal cell skin cancer?

What is squamous cell vs basal cell skin cancer?

Different growth: Basal cell skin cancers often grow deeper and more destructive when left untreated causing large ulcerated areas. Squamous carcinomas more often spread radially and have a higher risk of spread to other organs if left untreated. ...Read more

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Is a squamous cell something that forms squamous cell carcinoma?

Is a squamous cell something that forms squamous cell carcinoma?

Not necessarily: Squamous cells are normal constituents of skin and some of the other linings, e.g., vagina. Squamous cells per se do not give rise to any cancer. Some cancer have squamous cell features. ...Read more

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What is the difference between: basal cell carcinoma epithelioma, squamous cell carcinoma, and melanoma?

Skin cancer: The difference between basal cell carcinoma, squamous cell carcinoma, and melanoma has to do with how the skin cancer cells appear under the microscope as well as how they behave. Therefore it is important that they be diagnosed and treated as quickly as possible by a healthcare professional who specializes in this area. ...Read more

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Whats non-small cell carcinoma?

Whats non-small cell carcinoma?

Non Small cell ca: Is the most common type of lung cancer, another type is small cell ca (which is more aggressive). Both are challenging to diagnose at an early stage. Please consult with your oncologist for prompt diagnosis, and treatment options. Good luck. ...Read more

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Basal cell carcinoma multifocal superficial?

Excision: This type of basal cell needs excision with a 3-5 mm margin. Consult with your dermatologist or plastic surgeon. ...Read more

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What is poorly differentiated squamous cell cancer?

Very malignnt.: This is a kind of squamous cancer that is poorly organized, or has no resemblance to what squamous lining should look like. It follows that this is a very serious cancer that must be treated very aggressively for any chance of a favorable outcome. ...Read more

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Whats squamous metaplasia?

Whats squamous metaplasia?

Benign / worrisome: Usually this is a pap smear finding. Metaplasia is replacement of a normal mature tissue type with another normal mature tissue type, in the cervix the columnar epithelium in the endocervix replaced by a squamous type. It is usually caused by the hpv virus and depending on the strain may present a slightly increased risk for progression toward something that is actually dangerous. ...Read more

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Endocervical and/or squamous metaplastic cells?

Endocervical and/or squamous metaplastic cells?

Pathologist speak: This simply means that when the pathologist reviewed your pap smear it contained either normal cells from the inside of the cervical opening or cells that were not microscopically different in appearance from cervical cells. ...Read more

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Can invasive moderately differentiated squamous cell carcinoma of esophagus lead to death?

Can invasive moderately differentiated squamous cell carcinoma of esophagus lead to death?

It can: Esophageal cancer is very serious, and is a difficult cancer to treat. For your type, there's debate about the best treatment strategy (surgery vs chemoradiation vs all 3). Your specific prognosis will depend on the stage of disease, but esophagus cancer is always quite serious. Best of luck to you. ...Read more

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What are stages of squamous cell carcinoma?

What are stages of squamous cell carcinoma?

Differentiated: The pathology report will desribe well, moderate or poorly differentiated. Well differentiated is less advanced. It will also describe depth on invasion and whether nerves are involved. An evaluation of lymph nodes is done to confirm squamous cell is localized to skin. In advanced cases it will have spread requiring surgery followed by radiation, and possible chemotherapy. ...Read more

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Is a squamous cell something that forms squamous cell carcinoma?

Not necessarily: Squamous cells are normal constituents of skin and some of the other linings, e.g., vagina. Squamous cells per se do not give rise to any cancer. Some cancer have squamous cell features. ...Read more

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How risky is squamous cell carcinoma of the tonsil?

How risky is squamous cell carcinoma of the tonsil?

Depends: Early stage tonsil cancer due to hpv has a relatively good prognosis. Advanced cancer due to smoking, and alcohol has worse outcome. See this site for more information on oral cancers. http://www.cancer.gov/cancertopics/pdq/treatment/oropharyngeal/healthprofessional. ...Read more

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Can cyberknife surgery be used for squamous cell carcinoma?

Can cyberknife surgery be used for squamous cell carcinoma?

Cyberknife is: Not surgery, not a knife..It is a linear accelerator placed on a robotic arm to deliver stereotactic radiotherapy in high but very accurate arcs or beams to ablate anatomic abnormalities. It does not care about cell type. You need to discuss if it is appropriate for your sq ca; what the alternatives are; adverse effects; cost; who pays. ...Read more

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Is there a defiinite cure for stage 3 squamous cell carcinoma?

Is there a defiinite cure for stage 3 squamous cell carcinoma?

Need clarification: Stage 3 squamous cell carcinoma of ----? What organ? What kind of cancer ? Cervical? Head and neck cancer? Esophageal cancer? Lung cancer? Anal cancer? ...Read more

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Can a biopsy show how aggressive squamous cell carcinoma of the skin is?

Can a biopsy show how aggressive squamous cell carcinoma of the skin is?

Yes: The borders, the extent of invasion, the depth of invasion, if there is perineural (around nerves), intravascular (within vessels), mitoses (number of division bodies), and if there is necrosis (cell death): these are all measures of how agressive a cancer is. ...Read more

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What is the life expectancy of someone who has metastatic squamous cell carcinoma?

What is the life expectancy of someone who has metastatic squamous cell carcinoma?

It depends: A low-grade squamous cell carcinoma of the mouth metastatic to one neck lymph node may get a cure. A low-grade lung cancer with bone metastases may kill in a few days by causing pneumonia, or be compatible with a few years' survival. In real life, no physician says, "you have thus-and-so long to live". I hope that you will cherish each day of life that you are given, living richly & loving well. ...Read more

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How should I take care of my skin if I have had excision of squamous cell carcinoma?

How should I take care of my skin if I have had excision of squamous cell carcinoma?

Covered: Keep area covered and lubricated. Depending on rea avoid excessive movement. Do not wet area for about one week or until sutures are removed. Do not use any scar creams for the first 6- 8 weeks. Go to follow up visit, and go for routine visits to diagnosis an early skin changes. Use us screen and avoid mid day strong sun. ...Read more

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What would the life expectancy of someone with metastatic squamous cell carcinoma be?

What would the life expectancy of someone with metastatic squamous cell carcinoma be?

Uncertain: It is notoriously difficult to predict the life span in a given patient, especially without knowing all of the person's medical history. ...Read more

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Does chronic yearly sun exposure increase my risk for stage 3 squamous cell carcinoma?

Does chronic yearly sun exposure increase my risk for stage 3 squamous cell carcinoma?

Skin cancer: It is well established that chronic sun exposure increases ones risk of developing skin cancers including basal cell, squamous cell and melanoma. Smoking and alcohol can increase the risk of squamous cell cancers of the head and neck. ...Read more

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I was diagnosed with squamous cell carcinoma invading sclero corneal and deep. What surgical option is there vision 20 100 ?

I was diagnosed with squamous cell carcinoma invading sclero corneal and deep. What surgical option is there vision 20 100 ?

Needs treatments: Squamous cell carcinoma at sclera- corneal junction when invades ( no longer in situ bowman's , need staging of tumor also ) will need excision of conjunctiva 3 mm clear margin along with superficial layers of cornea , added cryotherapy will have lowest recurrence rate of 10 % , eye will be saved , some times chemo- therapeutic ointments are also used, speak to your doctor, . ...Read more

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I have just found out the person who I have been massaging for years has squamous cell carcinoma, could I have this also under my nails?

I have just found out the person who I have been massaging for years has squamous cell carcinoma, could I have this also under my nails?

No: You do not have to worry about squamous cell carcinoma just because one of your massage clients has been diagnosed with it. If you're concerned get a full body skin exam from your physician. ...Read more

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What is squamous cell carcinoma like?

What is squamous cell carcinoma like?

Depends on site: Squamous cell carcinomas of the skin are usually slow growing and metastasize only infrequently. Squamous cell carcinomas of the lung are lethal and a majority of the patients are dead within a year. Squamous cell carcinomas of the esophagus, cervix, oro-pharynx etc fall in between. ...Read more

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What is vasive squamous cell carcinoma?

"Invasive" - deeper: Skin squamous cell carcinoma (scc) often goes through stages of evolution on its way to becoming "invasive" and eventually metastasizing. It may begin as an area of sun damage or pre-cancer (actinic keratosis) and worsen to become a superficial scc that does not yet invade deeper (scc in situ). Eventually, the scc will start to go deeper and become "invasive", then metastasize if left unchecked. ...Read more

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Can you explain squamous cell carcinoma?

Can you explain squamous cell carcinoma?

SCC: Squamous cells are normal epithelial cells present in a layer of the skin called the epidermis. When the architecture of the cell is distorted, severely disorganized, and has uninhibited growth, it becomes a cancer. ...Read more

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What does squamous cell carcinoma mean to you?

Subtype of cancer: It only means-a subtype of cancer. Nothing much. The treatment, prognosis etc- will depend on where is this cancer located primarily? , what is the stage ( how big it is? Any lymph node or adjacent tissue involvement? Any spreading to distant organ? Etc. If you smoke tobacco and drink alcohol- you need to quit. Please discuss in detail with your oncologist. ...Read more

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How do a squamous cell and squamous cell carcinoma differ?

How do a squamous cell and squamous cell carcinoma differ?

SCC: Squamous cells are normal epithelial cells present in a layer of the skin called the epidermis. When the architecture of the cell is distorted, severely disorganized, and has uninhibited growth, it becomes a cancer. ...Read more

Dr. John Ebner
146 doctors shared insights

Squamous Cell Cancer (Definition)

By definition, these mimic the squamous epithelial surfaces of the body that provide protection. Keratin pearls, prominent desmosomes, apoptosis of individual cells, staining for the distinctive molecules in these surfaces all help ...Read more


Squamous Cell (Definition)

Describes the tile like architecture of cells; however, their behavior is deranged, nuclei irregualrly enlarged and ...Read more