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Doctor insights on: Erythrocytosis Megalosplenica

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Is autoimmune hemolytic anemia hereditary?

Is autoimmune hemolytic anemia hereditary?

No: It can be due to an underlying autoimmune disorder, such as lupus or rheumatoid arthritis. In this case, the underlying autoimmune disorder may be hereditary; but the autoimmune hemolytic anemia is not hereditary. It is simply the manifestation of the underlying disorder. There are also several causes of autoimmune hemolytic anemia that are not inherited. ...Read more

Dr. Angelica Balingit
199 doctors shared insights

Polycythemia Vera (Definition)

A slow-growing blood cancer in which the bone marrow makes too ...Read more


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Low hemoglobine, hematocrit&creatinine w/anisocytosis poikilocytosis anisochromia microcytes dianocytes schitocytes difusse basophilia, what it means?

Low hemoglobine, hematocrit&creatinine w/anisocytosis poikilocytosis anisochromia microcytes dianocytes schitocytes difusse basophilia, what it means?

Get it looked at: Your peripheral smear and your labs need to be reviewed by a hematologist or hematopathologist for accuracy of the lab report and possible diagnosis. It may be nothing more than minor genetic fluke, or something significant. Heads up -- vasculitis in the gall bladder wall is usually nothing to worry about though it scares some pathologists into overcalls. ...Read more

Dr. Liawaty Ho Dr. Ho
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Does nomochromic normocytic anemia indicate renal impairment?

Dr. Liawaty Ho Dr. Ho
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Does nomochromic normocytic anemia indicate renal impairment?

Not necessarily: Normocytic normochromic anemia can be caused by acute blood loss, early iron deficiency, bone marrow supression, anemia of chronic disease, anemia of renal insufficiency, anemia caused by endocrine problem etc. ...Read more

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Is polychromasia typically associated with microcytic anemia (iron deficient anemia)?

Is polychromasia typically associated with microcytic  anemia (iron deficient anemia)?

Iron deficiency is: Usually hypo chromic. Polychromasia is seen in rapidly changing circumstances like hemolytic anemia. ...Read more

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Is sickle cell anemia hereditary?

Is sickle cell anemia hereditary?

Yes.: it is an autosomal recessive disorder, meaning that both parents must be carriers of the mutation. If they are, the chance of each child being affected is 1 in 4. ...Read more

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Hb 10.3, platelets 105000, normoblasts=03/100wbcs. Rbcs morphology is normochromic. Normocytic majority of lymphocytes are atypical. Mononeuclear smal?

Hb 10.3, platelets 105000, normoblasts=03/100wbcs. Rbcs morphology is normochromic. Normocytic majority of lymphocytes are atypical. Mononeuclear smal?

We can't answer: Especially with the abnormal morphology of the lymphocytes, you need to speak either with the treating physician -- primary care or consulting hematologist -- or with a physician you trust. No one here can tell you what this means though it is of course very concerning. ...Read more

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Can normochromic or normocytic anemia cause leukemia?

Can normochromic or normocytic anemia cause leukemia?

No: Anemia (normochromic/cytic or not) can be a sign of leukemia (or a variety of other cancerous or non-cancerous conditions). That is it can associated with leukemia. However, it does not cause leukemia. Correlation does not equal causation. ...Read more

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Whats megaloblastic anemia?

Whats megaloblastic anemia?

Anemia: Megaloblastic anemia is anemia related most commonly to vitamin B12 and Folic Acid deficiency. These problems are easily treated with replacement of the deficient vitamin. There are other much rarer causes of megaloblastic anemia, and other illnesses that may look similar to megaloblastic anemia. ...Read more

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Pediatrics. IGM0.43 WBC4.1 RBC3.60 PLATELETS120 MCV107.0 MCH34.5 NEUTROPHIL0.66 MONOCYTE0.04 BRUISING EASY does this indicate MDS or APLASTIC AMENIA?

Pediatrics. IGM0.43 WBC4.1 RBC3.60 PLATELETS120 MCV107.0 MCH34.5 NEUTROPHIL0.66 MONOCYTE0.04 BRUISING EASY does this indicate MDS or APLASTIC AMENIA?

Easy bruise: These results do not point to an aplastic condition because there is normal WBC count and adequate platelets. They should have done labs for bleeding diathesis such as Prothrombin time(PT/INR) and Partial thromboplastin time (PTT) as well as possible blood clotting factor levels. ...Read more

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What is anemia megaloblastica?

Megaloblastic anemia: Megaloblastic anemia (or megaloblastic anaemia) is an anemia (of macrocytic classification) that results from inhibition of DNA synthesis during red blood cell production.[1]The defect in red cell DNA synthesis is most often due to hypovitaminosis, specifically a deficiency of vitamin B12 and/or folic acid. ...Read more

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Reticulocytes low, pancytopenia, & bone marrow destruction indicates which type of anemia?

Reticulocytes low, pancytopenia, & bone marrow destruction indicates which type of anemia?

Complex problem: It appears that your bone marrow is not making new blood, so you have anemia due to the failure of production. If you have pancytopenia then the problem is much more than anemia alone. Such situation are either due to leukemia or preleukemic conditions like Myelodysplastic syndrome(MDS). You need a blood specialist to help you sort it out and guide you further. ...Read more

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Does alpha thalassemia causes leukemia?

Does alpha thalassemia causes leukemia?

No: Alpha and beta thalassemia have not been reported to cause leukemia, which is cancer of the white blood cells. There is a study of beta thal. Major & intermedia patients in iran, where researchers found 5 leukemia cases in about 4, 600 patients. That is a higher rate of leukemia than in the general population there, but details were unavailable as to what other factors were present in the patients. ...Read more

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Ferritinin 800, iron 167. And macrocytic anemia. Liver , kidney, wbc, platelets, neutrophil, B12 normal. Why? Is it preleukemia?

Ferritinin 800, iron 167. And macrocytic anemia. Liver , kidney, wbc, platelets, neutrophil, B12 normal. Why? Is it preleukemia?

At least 2 problems: You realize that we can't diagnose you. With the very high serum ferritin and up-there serum iron, assuming the blood was not drawn during an acute illness, you have hemochromatosis until proved otherwise. How anemic you are, whether this is real macrocytosis, what your physical findings and other labs are are best known to your hematology consultation. Hope nobody gave you iron supplements. ...Read more

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What causes sickle cell anemia besides malaria?

What causes sickle cell anemia besides malaria?

Malaria doesnt cause: Sickle cell anemia is a hereditary disease caused by a mutation in the dna coding for hemoglobin. Scientists have long known that sickle cell anemia protects carriers from malaria infections, which could be advantageous in certain parts of the world. Malaria does not cause sickle cell anemia. ...Read more

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Whats a normocytic normochromic anemia?

Whats a normocytic normochromic anemia?

Normal looking cells: Normocytic means the red blood cells are normal size; normochromic means normal color (amount of hemoglobin which gives the red blood cells their red color. Anemia means you have fewer than the normal number of red blood cells. ...Read more

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Hypercellular Marrow,increased Trilineage Hematopoiesis,reactive lymphoplasmacytosis, Erythropoiesis normoblastic and decreased. Myeloblasts not increased Megakaryocytes increased, include young forms

Hypercellular Marrow,increased Trilineage Hematopoiesis,reactive lymphoplasmacytosis, Erythropoiesis normoblastic and decreased. Myeloblasts not increased Megakaryocytes increased, include young forms

Marrow confusion: Complex because the answer is dependent on the hematologists total examination and not just a marrow. There is a difference between dysmorphic cells and immature forms so no diagnosis can be made from your comments. Stick with the hematologist or concologist. ...Read more

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Adult male,bone marrow biopsy show Erythroid hyperplasia RBC borderline on high side,thrombocytopenia fluctuate, Splenomegaly,negative for infections.

Adult male,bone marrow biopsy show Erythroid hyperplasia
RBC borderline on high side,thrombocytopenia fluctuate,
Splenomegaly,negative for infections.

CBC Results: If you can send us the complete blood count (CBC) report which includes Hb, WBC, Platelet counts done from 2 different dates, we can tell you if there is anything serious or how to manage your concerns. WE need to know the number of platelets(Count). RBC numbers are not useful...instead we use hemoglobin as a better test to reflect any problems with RBCs. ...Read more

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Is chronic pancytopenia anemia curable?

Depends on cause: Chronic pancytopenia means low white & red cells and low platelets. Reversible causes such as nutritional deficinecies, immune disorders, drug-related can be treated effectively. However, patientsw with inherited conditions or bone marrow disorders need a detailed work-up and treatments may not be effective. ...Read more

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Is malaria and sickle cell anemia related?

Is malaria and sickle cell anemia related?

Sickle cell Trait: can offer some protective value regarding severity of malarial disease. In a person who has sickle-cell trait – the red blood cells are destroyed prematurely before the Plamodium can reproduce. According to one study “Sickle cell trait provides 60% protection against overall mortality. Most of this protection occurs between 2-16 months of life, before the onset of clinical immunity..." ...Read more

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How follic acid deficiency causes megaloblastic anemia?

It just does :): Hello- your body needs Folic Acid to make red blood cells properly. If you do not have enough it compromises the process. The body will not be able to produce red blood cells as well (anemia) and they will be bigger than normal red blood cells (megaloblastic = big). Thankfully some Folic Acid replacement should fix the problem quite easily. ...Read more

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