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Doctor insights on: Erbitux Colon Cancer

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How effective are Cetuximab injections for treating colon cancer?

How effective are Cetuximab injections for treating colon cancer?

Some response: Erbitux was one of the first monoclonals develoed. It targets epidermal growth Factor 1 and is used in metastatic colon Ca that has the wild mutated KRAS. The best response is like Herceptin (trastuzumab) where this epidermal growth factor 2 mAb requires added chemo. As such when Colon Ca is treated with Erbitux + chemo there is an improvement in response for a number of months. No cures have been seen. ...Read more

Dr. Barry Rosen
4,214 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Colon cancer fluid filled in stomach can anyone tell survival period?2nd line chemo going on...Cetuximab n folfri

Colon cancer fluid filled in stomach can anyone tell survival period?2nd line chemo going on...Cetuximab n folfri

Confused???: I do not know what you mean by colon cancer fluid in stomach are you talking about ascites which is a free fluid in the abdomen or there is an abnormal connection because of the cancer between the colon and the stomach either way this is an advance cancer if surgery is not an option chemotherapy do not do much for colon cancer simply follow your doctor instruction and hope for the best. ...Read more

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She is 59sept end 2013 we came to know tht she is having colon cancer stage 3.Then 6cchemos were given n in CT no improvement.Cetuximab goi survival?

She is 59sept end 2013 we came to know tht she is having colon cancer stage 3.Then 6cchemos were given n in CT no improvement.Cetuximab goi survival?

Be patient: Colon cancer is a preventable disease and the only treatment for it is surgery chemotherapy can help when the cancer is spread but containing the cancer is the key simply be patient and follow the doctor instruction and pray for the best. ...Read more

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Can this be colon cancer?

Can this be colon cancer?

Not enough info: Colon cancer can present with or without symptoms. Common symptoms include change in stool caliber/consistency, rectal bleeding or blood with bm, abdominal pain, anemia. If you have not been screened, you should consider the various screening options for colon cancer, includine a stool test to check for blood, colonoscopy, or sigmoidoscopy. If you are having bleeding, you need a colonoscopy. ...Read more

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How to know if colon cancer ?

How to know if colon cancer ?

Get tested: There are many tests that have been developed to test either a patient with concerning symptoms or just as a routine screening exam in an a symptomatic patient. Each individual situation is different. Testing stool for blood or now genetic abnormalities, rectal exam, X-rays such as barium enema or ct scan virtual colonoscopy are examples. Best is colonoscopy as you can both look and do. ...Read more

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What is the cause of colon cancer?

What is the cause of colon cancer?

Multiple factors: Age over 50, chronic intestinal diseases, polyps, diabetes, smoking, sedentary lifestyle, heavy alcohol consumption and filly history of cancer can all increase your risk. Majority occur due to acquired defects in cells lining the intestines from a combination of one or more factors. Small minority are hereditary. ...Read more

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How to know if I have colon cancer?

How to know if I have colon cancer?

Colonoscopy: Colonoscopy + biopsy as indicated. If you do have risk factors, you should have your first screening colonoscopy at age 50. ...Read more

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What are the stages of colon cancer?

What are the stages of colon cancer?

1 through 4: The stage of colon cancer is based upon the depth of penetration of the cancer thru the colon wall, the presence or absence of lymph node involvement, and the presence of cancer elsewhere in the body (metastatic disease). The stage is associated with prognosis and guides our recommendations regarding chemotherapy. ...Read more

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Dr. Eric Kaplan
921 doctors shared insights

Colon Cancer (Definition)

Final few yards of your intestine, between the terminal ileum (small bowell) and rectum. It squeezes water and solidifies waste to stool. It is subject to outpouching (divertics) polyps, and these can become cancers. The cells are abnormal, invade into the muscle and travel ...Read more


Dr. Louis Gallia
1 doctor shared a insight

Colon (Definition)

The colon is another term for the large intestine. This is the final portion of the digestive system, responsible for absorbing water and storing stool before evacuation. It is divided into sections described as cecum; ascending, transverse, descending and ...Read more