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Not exactly: Benadryl (diphenhydramine) is diphenydramine, an old first generation antihistamines that lasts about 6 hours and can cause drowsiness and other side effects. Claritin (loratadine) is a new generation antihistamine that can last 24 hours and has less side effects. At this time, there is no real advantage to benadryl, (diphenhydramine) unless a person also wants some sleep.... ...Read more
Zyrtec (cetirizine): Polaramine (dexchlorpheniramine maleate) (dexchlorpheniramine) is an older antihistamine that is not used as often due to dosing every 8 hours and side effects (impaired driving ability). Effectiveness of polaramine (dexchlorpheniramine maleate) was similar to Claritin (loratadine) while a study in healthy adults showed zyrtec (cetirizine) to be a better antihistamine than polaramine (dexchlorpheniramine maleate). Go to: http://www.Ncbi.Nlm.Nih.Gov/pubmed/2972549. ...Read moreSee 1 more doctor answer
Yes: Claritin is a second generation antihistamine which causes much less drowsiness than first generation antihistamine, like benadryl (diphenhydramine). The number of people who feel drowsy on Claritin is so low that it is labeled "non-drowsy". But each of us is unique. I have plenty of patients who feel drowsy on claritin, especially petite women. ...Read moreSee 1 more doctor answer
What antihistamine would be comparable to fexofenadine (allegra)? Is Claritin (loratadine) or zyrtec comparable?
Anti histaminic: Claritin (loratadine) is a prescription anti-histaminic (anti-allergic) medication which has less of a tendency to cause sleepiness as a side effect. Diphenhydramine (benadryl) is not in Claritin (loratadine) but it is an over the counter anti-histamine of slightly higher potency than claritin, (loratadine) but a much stronger tendency to cause drowsiness. ...Read more
Work differently: Claritin in a non-drowsy antihistamine. It doesn't cause sleepiness, but you need to use it every day for it to work really well. It's lousy for severe allergic reactions because it takes days to be fully effective. Benadryl (diphenhydramine) causes drowsiness and only lasts for six hours, but is great for severe allergic reactions and works very quickly. If you're exposed and need help now, Benadryl (diphenhydramine) is better. ...Read moreSee 1 more doctor answer
Antihistamine: Benadryl, (diphenhydramine) polaramine, chlortrimeton etc., are old time antihistamines used for runny nose, sneezing, itching, and other allergies. They are very effective but can cause drowsiness and should be avoided in day time. Carefully read all the side effects. Zyrtec , Claritin & Allegra are newer antihistamines, with lot less drowsiness or other side effects. They work fairly well for most people. ...Read moreSee 1 more doctor answer