Doctor insights on:
Epidermal Growth Factor Ihc
Yes: Vascular endothelial growth factor (vegf) is a substance that cells produce which helps them recruit the growth of new blood vessels. Blood vessels are essential in bring normal cells and cancer cells the oxygen and nutrients they need to keep growing. The growth of some types of cancer can be slowed or controlled by blocking vegf. ...Read moreSee 1 more doctor answer
Is a neurofibroma tumor 2.5 CM in size positive for s100, pgp9.5, NSE, factor XIIIa, CD 34, desmin, and SMA cancer? Negative for CD68.
KGF and hair growth: Abstract keratinocyte growth factor-2 (kgf-2) is found in dermal papilla fibroblasts and its receptor, fibroblast growth factor receptor 2 (fgfr2), in the neighboring outer root sheath of keratinocytes. Administration of recombinant human kgf-2 (rhkgf-2) at 10 ng ml(-1) significantly stimulated human hair-follicle cell proliferation in organ culture (26-35%). Thus, rhkgf-2 is a promising therapeut. ...Read moreSee 1 more doctor answer
Yes: Vascular endothelial growth factor (vegf) is a substance that cells produce which helps them recruit the growth of new blood vessels. Blood vessels are essential in bring normal cells and cancer cells the oxygen and nutrients they need to keep growing. The growth of some types of cancer can be slowed or controlled by blocking vegf. ...Read more
Fundamental!: All living things need a blood supply to deliver food, water, and get rid of waste. A circulating cancer cell needs to evade detection, get out of the blood vessel, and establish that blood supply: angiogenesis!. All these actors under molecular control, and likely normal during in utero development. Cut off the blood supply, choke the tumor. ...Read more
Very seldom: People who are carriers for ataxia-telangiectasia are at extra risk for some of the non-hodgkin's lymphomas, but there's no knowing if this is you. One double mch2 syndrome also produces lymphomas. Beyond this, and a very weak tendency for lymphomas to be diagnosed in family members (maybe we look harder), evidence that lymphoma is hereditary is conspicuously lacking. ...Read moreSee 1 more doctor answer
Is there any correlation between h/o breast & cerv cancer, and growing lumbar hemangioma & adenomatous & hyperplastic colon polyps, w/o cancer gene?
None of these: Are linked genetically, to environmental exposures, or familial clusters. ...Read more
Tumor: Monoclonal proliferation of lymphoid cells is usually an indication of tumor of the lymphoid tissue. ...Read more
Tamoxifen: Tamoxifen has been the standard drug that blocks estrogen receptors in patients whose tumors are considered ER+ A new type of anti-estrogen drug appears to work better than the estrogen-blocking drug tamoxifen . Exemestane (Aromasin), belongs to a class of drugs called aromatase inhibitors. But, for exemestane to work in premenopausal women, the drug can only be given when ovarian function is being suppressed.The Aromatase inhibitors, work by preventing other hormones from changing into estrogen, which fuels certain cancer growths ...Read more
Tough question: If you mean hereditary, there are a few families that have a high incidence of lymphomas. If you mean, are there changes in the dna in lymphoma - the answer is yes...Several types of lymphoma have distinct mutations that can be easily found in a biopsy specimen. Also, individual patient's tumor genes can be analyzed by a technique called micro-array which shows common patterns in survival. ...Read moreSee 2 more doctor answers
Stimulate reaction: Tumor necrosis-alpha , ( tnf) also known as cachexin or cachectin is a cytokine mainly secreated by macrophages stimulates the acute phase of inflamation. Tnf regulates the immune cells, performs varieties functions as pyrogen ( causing fever ), regulates cell proliferation, differentiation, apoptosis ( cell death or suicide ) , in lipid metabolism, in coagulation of blood etc. ...Read more
What does benign follicular cells in mixed micro macrofollicular pattern, focal hurthle cell changes histiocytes mean? 3cm nodule on thyroid fast grow
Discuss: For a 3 CM fast growing thyroid mass, there is a higher chance of false negative with the biopsy. Not all the mass could be cancerous and the cancer spot could have been missed during fna because the mass is big at 3 cm. Most prudent step now is to follow for size changes and rebiopsy if it changes in 1 year. Depending on your age and current compressive symptoms, surgery is an option. ...Read moreSee 1 more doctor answer
Pathologic diagnosis....Resected thymus shows reactive b cell hyperplasia vs low grade b cell lympho proliferative disorder. Is this lymphoma?
Could be...: Certain lymphomas grow so slow that sometimes it is difficult for the pathologist to make the call between malignant or not. I suspect they may do additional work on the specimen and that your doctor will evaluate you further with labs, additional scans or another biopsy. If you have not seen a hematologist, maybe this is the time. Don't panic, just follow up his/her lead. Best to you. ...Read more
Not necessarily : It would be extremely unlikely to occur ...Read more
ACTUALLY IT CAN BE: There are some genetic abnormalities that predispose people to have sarcoma- for instance: li- fraumeni syndrome- where there is 7% risk for sarcoma; gardner syndrome/fap- related to high frequency of intraabdominal desmoid tumor, retinoblastoma is associated with osteosarcoma, rothmund-thomson syndrome (poikiloderma congenitale) is associated with osteosarcoma- etc. ...Read moreSee 1 more doctor answer
There are: literally millions of genes that control cell growth not only in pancreatic tissue but throughout the entire body. Why do you ask? ...Read more