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Doctor insights on: Enlargement Liver Spleen

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Dr. Neigatha Graney
2 doctors shared insights

Liver (Definition)

This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more


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Is it possible for galbladder disease to cause spleen or liver enlargement?

Is it possible for galbladder disease to cause spleen or liver enlargement?

No: There would be no association of the gallbladder that i can think of that would cause liver damage to the point of liver enlargement, cirrhosis, or spleen enlargement. ...Read more

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I have enlarged spleen and enlarged liver and sugar count was 375 . Typ 2 diabeties, tx includes med every day. The enlargements just started 2 weeks?

I have enlarged spleen and enlarged liver and sugar count was 375 .  Typ 2 diabeties, tx includes med every day. The enlargements just started 2 weeks?

Not the spleen: By itself, uncontrolled diabetes can cause a 'fatty' liver with enlargement but splenomegaly is not generally associated with diabetes per se. ...Read more

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3 yr old TPN dependent for 2 yrs. She has splenomegaly (measured 8.9) alt/ast looks great. Can TPN cause spleen enlargement w/out affecting liver?

3 yr old TPN dependent for 2 yrs. She has splenomegaly (measured 8.9) alt/ast looks great. Can TPN cause spleen enlargement w/out affecting liver?

Doubtful, but: I have never seen TPN cause isolated splenomegaly without some involvement of the liver, but i would defer the final answer to a peds GI doc. However, i would be more concerned that whatever underlying condition that is causing her to be TPN dependent and not able to use her gut is contributing to her splenomegaly, and not the TPN itself. ...Read more

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I have too much extra copper in my body. Because of that my liver and spleen are large. What are my options.....?

I have too much extra copper in my body. Because of that my liver and spleen are large. What are my options.....?

Wilson's disease: There are chelating therapy available.....being young....your chances are better..... oral penicillamine with pyridoxine,indefinitely. Alternately, trientine. oral zinc interferes with copper absorption in gut. It is an autosomal recessive, watch with whom you shire a child....... ...Read more

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What would cause a spleen and liver to be inflamed?

What would cause a spleen and liver to be inflamed?

More info needed: but usually enlargement of both spleen and liver is due to "portal hypertension", which is most commonly due to cirrhosis of the liver. ...Read more

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If spleen is removed does the liver take over all functions or do any of the serious functions get lost? Also since liver works more, overstressed?

If spleen is removed does the liver take over all functions or do any of the serious functions get lost? Also since liver works more, overstressed?

Not completely, & no: There is much duplication within the immune system. That said, the spleen is important, especially for handling certain bacteria. Special vaccinations should be given, if not before, definitely after splenectomy. Liver also is part of the reticulo-endothelial system, but it will work just fine if the spleen has to be removed. ...Read more

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I have had pain radiating from the front to the back over the liver (and the other side (spleen side - but just in back there), for the past few days.

I have had pain radiating from the front to the back over the liver (and the other side (spleen side - but just in back there), for the past few days.

RUQ pain: Could be gallbladder or gastritis with or without H pylori a bacteria. May need antibiotics or if gallbladder surgery. . Could also be acute hepatitis from medicaitons ,alcohol, or pancreatitis from blockage due to gallstone or medication or alcohol. F/u/ w/ doc. ...Read more

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How can I tell if my liver or spleen is swollen?

Physical exam: Perhaps the best place to start with determining if your liver or spleen is enlarged or abnormal is with a physical examination from a skilled provider such as a primary care physician. Such a person can take a history from you and then examine your body. If after that, there are questions left unanswered, imaging studies such as an ultrasound and/or a few lab tests might be helpful. ...Read more