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Doctor insights on: Enlarged Spleen With Mononucleosis

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Dr. Heidi Fowler
391 doctors shared insights

Infectious Mononucleosis (Definition)

Mononucleosis is a viral disease caused by EB Epstein Barr virus. It can last 10-14 days even up to weeks and become chronic on occasion. A mono assay test can reveal if present and on an CBC can see nucleated or atypical lymphocytes. Sore throat, fatigue, fevers are the main symptoms. Treatment remains bedrest, fluids and Advil 400 mg po q 6 hrs until no symptoms occur. Reg ...Read more


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Will smoking marijuana rupture your spleen if you have an enlarged spleen from mononucleosis (recreational use only)?

Will smoking marijuana rupture your spleen if you have an enlarged spleen from mononucleosis (recreational use only)?

Marijuana: Health: Nope. Absolutely not. I would be curious where you got this myth. Marijuana is an herb that is used to stimulate hunger in those not eating, to calm a stomach in crisis with nausea, vomiting or cramping. It is less dangerous than alcohol or other illicit substances. It does have an addictive potential and so recreational use should not be something done every day. ...Read more

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If i had elevated liver enzymes and enlarged spleen due to mononucleosis, how long do I need to wait to drink alcohol?

If i had elevated liver enzymes and enlarged spleen due to mononucleosis, how long do I need to wait to drink alcohol?

How do you feel?: You'll know when you're ready because you'll feel fully recovered. I hope you're not in any hurry, and that for the rest of your life you'll drink sensibly. ...Read more

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Is it safe to sleep on my stomach while I have an enlarged spleen/liver from infectious mononucleosis?

Is it safe to sleep on my stomach while I have an enlarged spleen/liver from infectious mononucleosis?

Yes: Your body has quite a tolerance when it comes to illness & it would let you know if it didn't like sleeping on your belly by not allowing it. I'd avoid bicycle riding, jogging, or contact sports, anything where you could fall & traumatize both organs, until their swelling subsided. ...Read more

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How long does the spleen stay enlarged during mononucleosis ?

How long does the spleen stay enlarged during mononucleosis ?

3-6 months: It can take 3-6 months for the enlargement of the spleen to go away after having mononucleosis. ...Read more

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My spleen is enlarged from mononucleosis and i'm on an antibiotic called cephadroxil..Will smoking recreational marijuana rupture my spleen?

My spleen is enlarged from mononucleosis  and i'm on an antibiotic called cephadroxil..Will smoking recreational marijuana rupture my spleen?

No: I'd give all recreational drugs and all unnecessary drugs a rest while you are recovering from your mono and while you are on antibiotic treatment which suggests you also have a bacterial infection. ...Read more

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If you have an enlarged spleen from mono, can you feel it?

Depends: It depends on how big it is... If it is big enough for you to feel... You need to see a doctor and avoid any activities that may put you at risk for rupture of the spleen. ...Read more

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If I have an enlarged spleen from mono, should I wear a seatbelt?

Yes, please!: The spleen is one of the most common organs injured following car crashes. It is common for the spleen to enlarge with mono; this makes you more susceptible to splenic injury. Wearing a seat belt will decrease your risk of trauma to the spleen. ...Read more

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Ultrasound to check gallbladder showed enlarged spleen? Nurse gave me the values 9.3 and 480 upper limit but didn't elaborate. Recommended mono test?

Enlarged spleen: needs a work-up and mono is one of the more common causes for the acute enlargement. If negative, then other potential causes need to be considered. ...Read more

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What causes an enlarged spleen? Do not have mono.

What causes an enlarged spleen? Do not have mono.

SPLENOMEGALY: CAUSES: Many: though not that common. Typhoid, septicemia, abscess/cyst in spleen, some viral infection, malaria, toxoplasma infection; hemolytic anemias- e.g. Thalassemia, sickle cell anemia, hereditary spherocytosis; lymphoma, leukemia; some metabolic diseases; liver cirrhosis with portal vein hypertension; sarcoidosis; rheumatoid arthritis. Sound scary, if feeling too sick, check with your doctor. ...Read more

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I am getting mono, enlarged spleen, symptoms etc.?

I am getting mono, enlarged spleen, symptoms etc.?

Yes...: Mono is a viral illness...Chinese medicine is amazing in helping recover form mono and i would suggest it highly. ...Read more

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Do all people with mono have enlarged spleen and lymph glands?

Most: There are many variations in the clinical manifestations of mono and it may not cause any symptoms. Most people with clinical mono do have enlargements of lymph nodes, spleen and liver and these subside on their own with the natural resolution of the infection in an otherwise healthy person. ...Read more

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Can i get advice? I've got and enlarged spleen but no mono and blood test look ok what could it be?

Can i get advice? I've got and enlarged spleen but no mono and blood test look ok what could it be?

Further tests ?: An ultrasound may help. Liver function tests can rule things out. Other viruses can cause this. If increasing in size, this will need definite evaluation and further work up. ...Read more

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Do some children gets an enlarged spleen with all viruses? My son already had mono but he seems to get a slightly enlarged spleen whenever he's sick.

Do some children gets an enlarged spleen with all viruses? My son already had mono but he seems to get a slightly enlarged spleen whenever he's sick.

Not with all viruses: Mononucleosis does cause splenic enlargement but all viruses do not cause splenic enlargement.But there are others beside the Ebstein Barr Virus which causes mononucleosis.Cytomegalo virus causes it.But you say it get enlarged whenever he is sick.I suggest you discuss with your pediatrician if it is of concern.If it goes down after his illness .then I see no problem.Discuss with his Pediatrician ...Read more

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I've an enlarged spleen from mono. I bumped my stomach on the kitchen counter today. Is it possible I ruptured my spleen?

I've an enlarged spleen from mono. I bumped my stomach on the kitchen counter today. Is it possible I ruptured my spleen?

Possible: How do you feel? Splenic rupture is usually accompanied by signs of shock like rapid pulse, low blood pressure and abdominal pain. If you begin experiencing these signs, you should seek medical attention immediately. Thanks for HealthTap! ...Read more

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I have an enlarged spleen, drenching night sweats, a cough, and slight difficulty breathing. I have no way to be seen, but what could this be? mono?

I have an enlarged spleen, drenching night sweats, a cough, and slight difficulty breathing. I have no way to be seen, but what could this be? mono?

Don't think is mono: If it was mono, your most prominent symptoms would be fatigue, sore throat, difficulty swallowing and very swollen neck glands. You did not mention any of those. How do you know you have an enlarged spleen? Now, any difficulty breathing is of concern, since it can go from mild to bad to worse any minute- allergy, asthma? Get medical attention for that breathing problem! ...Read more

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Enlarged spleen and diverticulosis. Any link? Both dx'd late teens, worstened over 20 yrs. Past tests neg. (mono, Crohn's). Will be seeing new doc

Enlarged spleen and diverticulosis. Any link? Both dx'd late teens, worstened over 20 yrs.  Past tests neg. (mono, Crohn's). Will be seeing new doc

No really.: There are many reasons for Enlarged spleen from Infectious etiology to Neoplastic. As you have been under care of doctor, these must have been screened and monitored. Diverticulosis of Intestine is benign condition. Good luck with the new doctor. ...Read more

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I was diagnosed with mono 4 days ago. And my spleen is enlarged. Will it go down on its own? Is garlic good for an enlarged spleen?

Yes: An enlarged spleen is seen in 50 to 60 percent of patients with infectious mononucleosis and usually begins to recede by the third week of the illness. I don't believe taking garlic will alter the course, symptoms, or signs of infectious mono. ...Read more

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My daughter has had mono. I'm pretty sure that I have had it as well. I am just literally exhuasted. All i want to do is sleep. My concern is that for the past few days my lower abdomen has felt strange. I know that you can get an enlarged spleen with mon

My daughter has had mono. I'm pretty sure that I have had it as well. I am just literally exhuasted. All i want to do is sleep. My concern is that for the past few days my lower abdomen has felt strange. I know that you can get an enlarged spleen with mon

You : You are correct regarding an enlarged spleen with mono. The spleen is located on the left side of the abdomen, closer to the middle; it is also closer to your back than your abdominal wall. If your spleen is enlarged and causing you pain, there is the possibility that this pain is radiating to the area you described. You must also consider that this may represent a different process, possibly a UTI (urinary tract infection). For this reason you should see your doctor for an evaluation and testing for mono as well as testing for a possible uti. Lastly remember to drink plenty of fluids and in the meantime avoid any contact sports or strenuous exercise. Take care. ...Read more

Dr. Michael Ein
764 doctors shared insights

Mono (Definition)

Infectious mononucleosis, also known as mono, is a contagious illness caused by the Epstein-Barr virus. Symptoms include fever, fatigue, sore throat, enlarged lymph nodes, and enlarged spleen. It is spread via saliva, hence its ...Read more


Upper Abdomen (Definition)

Draw a transverse line through the umbilicus and the upper abdomen includes every part of the belly above this line and below the ...Read more