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Doctor insights on: Enlarged Liver Enzyme Associated Disease Lymphoma

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Dr. William Singer
2 doctors shared insights

Liver (Definition)

This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more


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Is an enlarged liver enzyme is more associated with graves' disease or lymphoma?

Depends: Liver enzyme elevations reflect liver cell injury. Certain medications used to treat graves disease can affect the liver and periodic liver enzyme checks are warranted. Certain lymphomas can involve the liver and therefore can cause enzyme elevations. ...Read more

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Can Celiac disease cause very high liver enzymes?

Depends!: Elevated liver enzymes can be due to a number of different conditions. They can even be elevated temporarily for no reason, & fall to normal the next time it is checked. Are you on any meds? Do you feel bad? There isn't enough info to give you a decent answer. Give a little more history, and add any meds or other medical problems that you have in your health history and it will help us answer ...Read more

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Does liver disease cause parotid swelling?

Does liver disease cause parotid swelling?

Usually not: Generally no, but there are many things which can cause swelling of the parotid glands (spit glands in the cheeks). You should have it checked out by your md, but in general, painful swelling of the parotid glands can be initially treated with hot compresses, good hydration (lots of water) and sour foods/liquids taken 5-10x/day (vinegar, lemon juice, sour candies, etc). ...Read more

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Ace levels high, liver enzymes high, possible sarcoidosis dx, can sarcoidosis cause fatty liver on ultrasound. Dr scheduling liver& lymph biopsy.

Ace levels high, liver enzymes high, possible sarcoidosis dx, can sarcoidosis cause fatty liver on ultrasound.  Dr scheduling liver& lymph biopsy.

Sarcoidosis - Liver: The most common radiographic finding of hepatic sarcoidosis is hepatomegaly. Ultrasound can show diffuse increased homogeneous or heterogeneous echogenicity in hepatic sarcoidosis appearing similar to fatty liver. Focal liver nodules (thought to represent coalescence of small granulomas) can also be seen in hepatic sarcoidosis. Liver involvement by sarcoidosis typically responds well to steroids. ...Read more

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LIVER ENLARGED & ECHOGENIC CONSISTENT WITH NONSPECIFIC HEPATIC PARENCHYMAL DISEASE SUCH AS STEATOSIS. NO FOCAL MASS IS SEEN.Spleen size 16cm??

LIVER ENLARGED & ECHOGENIC CONSISTENT WITH NONSPECIFIC HEPATIC PARENCHYMAL DISEASE SUCH AS STEATOSIS. NO FOCAL MASS IS SEEN.Spleen size 16cm??

See doctor: The size of the spleen is of note. This enlarges for many reasons. The liver also enlarged is of concern as well. There should be a coordinated laboratory values to help make sense of imaging results. Not a good idea to speculate on cause without more data. Speak to your doctor for more data ...Read more

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Is hepatitis b infection associated with liver cancer?

Is hepatitis b infection associated with liver cancer?

Yes: Unlike most viral hepatitides, hepatitis b is associated with liver cancer regardless of the presence of cirrhosis. Therefore, blood test (i.e. Alpha-fetoprotein) and imaging study (i.E abdominal ultrasound) are recommended every 6 months beginning at the age of 40. ...Read more

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Panc elastase test shows insufficiency. Have fatty liver. Is pei cause of fatty liver? Is there connection between fatty liver and pancreatic cancer?

Panc elastase test shows insufficiency. Have fatty liver. Is pei cause of fatty liver? Is there connection between fatty liver and pancreatic cancer?

No, just description: Like most dx, just a label for a pattern, as judged by whatever metrics. Yes, there is observed relation between fatty liver ; developing liver cancer. Fatty liver most commonly due to persistent low-fat, hi-carb (i.e. All sugars, simple ; complex) foods. Liver, to protect rest of body from ?sugar (toxic), converts sugars into triglyceride fats. If can't export into external fat, then fatty liver. ...Read more

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Could elevated liver enzymes be a sign of liver cancer?

Could elevated liver enzymes be a sign of liver cancer?

While it could: Enzymes (alt/ast) indicate liver cell injury/inflammation: hepatitis - from viruses to drugs to alcohol. Alk phos may point to duct obstruction. But these can all be up or none be up in cancer traveled to the liver. ...Read more

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What causes an inhomogeneous spleen in hodgkin lymphoma?

What causes an inhomogeneous spleen in hodgkin lymphoma?

Lymphoma vs. other: The spleen in hl may be heterogeneous/inhomogeneous/non-uniform due to lymphoma involvement, spleen infarction (death) due to cancer death in the spleen, or infection, or "other". The radiologist may or may not be able to determine that and your oncologist might be able to say more about it with knowing the clinical history. ...Read more

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What can cause inhomogenous spleen in hodgkin lymphoma?

What can cause inhomogenous spleen in hodgkin lymphoma?

Lymphoma in spleen: Inhomogenious spleen refer to a ct scan reading where different area of the spleen might have different texture. In general some of these cases are nonspecific, some are related to ifarction (dead tissue) and some are related to lymphoma. In this case, if the patient is already diagnosed with hodgkins lymphoma, most probably these area are lyphoma in the spleen surrounded by normal spleen tissue. ...Read more

Dr. Ziad Akl Dr. Akl
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Increased /coarse hepatic parenchymal echotexture (liver parenchymal disease ) with prominent portal vein and splenomegaly? Wat it means

Dr. Ziad Akl Dr. Akl
2 doctors agreed:
Increased /coarse hepatic parenchymal echotexture (liver parenchymal disease ) with prominent portal vein and splenomegaly?  Wat it means

Severe damage: When damage to the liver occurs for a long time, meaning years, the liver becomes scarred and the veins that bring blood to the liver become distended because of resistance inside the liver. This increased pressure causes the spleen to take more blood and become enlarged. This is called cirrhosis of the liver and can be due to any number of things including alcohol and viral hepatitis. ...Read more

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What is chronic liver parenchymal disease with cirrhosis; varices and ascites?

What is chronic liver parenchymal disease with cirrhosis; varices and ascites?

This sounds serious: To translate, you have liver cell damage and scarring (cirrhosis), which caused abnormally elevated portal vein pressures which caused venous distention in esophagus (varices). You also developed fluid in abdominal cavity, because of the high portal vein pressure. This imaging study is showing advanced stage of liver disease. You must get a specialist to treat you. ...Read more

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What causes an inhomogenous spleen in hodgkin lymphoma?

What causes an inhomogenous spleen in hodgkin lymphoma?

Spleen involvement: Spleen involvement from hodgkin's lymphoma can give you heterogeneous/inhomogenous appearance of the spleen in the ct scan. A pet scan will tell you whether this is involvement from hodgkin's lymphoma or rather from other causes. ...Read more

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What is the prognosis of liver cirrhosis with stage 4 liver cancer? Why people with liver cirrhosis/liver cancer have low hemoglobin, red blood cells?

What is the prognosis of liver cirrhosis with stage 4 liver cancer? Why people with liver cirrhosis/liver cancer have low hemoglobin, red blood cells?

Need to ask your ono: Your oncologist can help. Anemia can be caused by blood loss(which is common in patients with cirrhosis(GI blood loss due to varices). Poor blood formation is also common(Anemia of chronic disease). Blood transfusion can help the pateint. Keep Hemoglobin near 10 Grams. There is some treatment for Liver cancer that could be tried(the medicine is called Nexavar(Sorafenib) ...Read more

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Does liver damage and disease always involve high or abnormal liver enzymes?

Does liver damage and disease always involve high or abnormal liver enzymes?

No: You can have chronic hepatitis B or C with normal liver enzymes. You can also have other chronic liver conditions, such as cirrhosis of the liver, with normal liver enzymes. ...Read more

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Can wilson's disease present as fatty liver or nash?

Can wilson's disease present as fatty liver or nash?

Absolutely: Wilson's is infamous for mimicking alcoholic liver disease and nash, with a lot of fat. This is a terrible blunder but i'm afraid it happens. Wilson's is deadly, treacherous, and the screening labs are often misleading. Screening for it should be done early in a liver workup that presents any ambiguities. ...Read more

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Is an enlarged liver enzyme is more associated with graves' disease or lymphoma?

Depends: Liver enzyme elevations reflect liver cell injury. Certain medications used to treat graves disease can affect the liver and periodic liver enzyme checks are warranted. Certain lymphomas can involve the liver and therefore can cause enzyme elevations. ...Read more

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U/s shows "mildly, enlarged liver 17cm prob due to fibrofatty disease" all labs and liver enzymes normal.. How would this be interpreted?

U/s shows "mildly, enlarged liver 17cm prob due to fibrofatty disease" all labs and liver enzymes normal.. How would this be interpreted?

Fatty liver: You have fatty liver from a poor diet and/or chronic alcohol use (even with normal liver enzymes). So, cut back from alcohol, improve your diet, and exercise. This will reduce the progression of your liver disease. ...Read more

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9 yr old f enlarged liver, 6 liver enzymes hi, hi bilirubin, hep abc -, cmv-, mono-.1 mon later enzymes lower&hi cholest., now hi alp&triglycer. Help?

9 yr old f enlarged liver, 6 liver enzymes hi, hi bilirubin, hep abc -, cmv-, mono-.1 mon later enzymes lower&hi cholest., now hi alp&triglycer. Help?

See Your Doctor: Symptoms like these are best determined by a thorough evaluation by your physician. Based on his/her findings, a treatment plan can be developed to help you. ...Read more

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Ultrasound showed enlarged liver and spleen. Ct results 6 days later showed my liver grew 3 cm. liver enzymes are normal. Need direction. Thanks?

Ultrasound showed enlarged liver and spleen. Ct results 6 days later showed my liver grew 3 cm. liver enzymes are normal. Need direction. Thanks?

How do you FEEL?: And why did you have the ultrasound done? Liver size varies from hour to hour depending on blood volume and whether you're digesting dinner versus running a marathon. Three percent of humankind have a palpable spleen for no obvious reason. Some folks have a low-slung liver that's easy to feel; others have a biggish or odd-shaped right lobe. Doubt this exploration will find anything worth treating. ...Read more

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Can acute hepatitis be a sign of permanent liver disease even if liver enzyme levels go back to almost normal?

Can acute hepatitis be a sign of permanent liver disease even if liver enzyme levels go back to almost normal?

Acute hepatitis: Is a form of liver disease. Most people recover from acute viral hepatitis. Unfortunately some cases progress to chronic aggressive form of disease, which can lead to cirrhosis. So have your doctor keep an eye on you. ...Read more

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Can acute hepititis be a sign of liver disease even if liver enzyme levels go back to near-normal?

Can acute hepititis be a sign of liver disease even if liver enzyme levels go back to near-normal?

Depends on cause: Almost all people recover completely from hep a, about 80% recover fully from hep b, only about 20% recover fully from hep c. Other causes of hepatitis, such as cmv, mono are usually transient. Alcoholic hepatitis and non-alocholic steatohepatitis can lead to permanent damage, . ...Read more

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What diseases could a 'liver enzyme screen' show?

What diseases could a 'liver enzyme screen' show?

Liver function tests: LFTs (SGOT, SGPT) will not specifically tell you what is causing the liver dysfunction. Rather they are indicators of abnormal liver function and additional studies including hepatitis panel, liver ultrasound, may be necessary. ...Read more

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My latest liver enzyme tests showed I have ALT 11 and AST 20. I have read that a 2:1 ratio of AST to ALT is indicative of liver disease and my numbers are pretty close to that. Can you tell me your thoughts on this? I am a 29 year old female who does drin

My latest liver enzyme tests showed I have ALT 11 and AST 20. I have read that a 2:1 ratio of AST to ALT is indicative of liver disease and my numbers are pretty close to that. Can you tell me your thoughts on this? I am a 29 year old female who does drin

Alcohol>BreastCancer: An ALT of 11 and AST of 20 is normal. The ratio pertains to alcoholic liver disease with abnormally elevated levels and is not an indicator of liver disease by itself. A far more sensitive test is Gamma-glutamyl transpeptidase(GGT). **There is an increased risk of breast cancer in women who drink, even lightly. The risk goes up 30% for each ounce of liquor, each 8oz beer or 5oz wine. ...Read more

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BMI 32, glucose intolerant, had baby 18 mo ago, all labs and enzymes nml-- am I to young for fatty liver? u/S says mild enlarged liver 17cm.

BMI 32, glucose intolerant, had baby 18 mo ago, all labs and enzymes nml-- am I to young for fatty liver? u/S says mild enlarged liver 17cm.

BMI 32: 1: You need to go on diet and also increase your exercise. 2: No adult is too young for fatty liver. You must discuss this carefully with a liver specialist. Your primary doctor can refer you. ...Read more

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What cause weight loss and borderline enlarged liver. Ultasound showed fatty liver but nothing else. All blood work good. Enzymes great. All heps ok.?

Obesity,wt loss: Welcome back. Don't know your current weight. You have lost over 60 pounds since march. What was weight then, now? Still overweight? That could still explain the fatty, enlarged liver. Previously, you stated all tests, including various imaging tests were normal: reassuring. ...Read more

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My liver in CT scan measures 19 cm, and the blood test (viral & enzymes) were normal. is this a major enlarged liver and what is the the normal size?

My liver in CT scan measures 19 cm, and the blood test (viral & enzymes) were normal. is this a major enlarged liver and what is the the normal size?

Need more info: Although at your age we do t expect the liver be enlarged. So it needs further investigation. Is your body weight more than usual. Is it a fatty liver. You need to know the cause of enlargement and don't get caught up into size. Once you know the reason and fix it then it will come back to normal. I hope that help. ...Read more

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Enlarged liver and spleen and elevated enzymes since birth. They think rubella since my antibody was negative in early pregnancy. Could it be?

Enlarged liver and spleen and elevated enzymes since birth. They think rubella since my antibody was negative in early pregnancy. Could it be?

Could be: Many congenital infections could cause those symptoms. Blood tests can usualky tell for sure, but maybe not for a few months. ...Read more

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I have elevated liver enzyme levels and was on Dioycycline for 5 months (from Nov. 2016 - March, 2017). They have come down but are still high. Do y?

I have elevated liver enzyme levels and was on Dioycycline for 5 months (from Nov. 2016 - March, 2017).  They have come down but are still high.  Do y?

Give us the results: If you can send us the present results of your liver Function tests(LFTs) we can be more helpful to you. Most often the liver enzymes will normalize if the offending agent has been removed from your body. ...Read more

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Can tres orix forte syrup cause increase liver enzyme?

Yes: The syrup is a proprietary blend of a Multi-Vit + Cyproheptadine. Cyproheptadine is a Histamine H1 Antagonist. Commonly used for Perennial and seasonal allergic rhinitis and other allergic symptoms. There is a report of Hepatic: Cholestasis, hepatic failure, hepatitis, jaundice. Though the frequency of these adverse events is not defined. Consult your GP for further evaluation and workup. ...Read more

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Dr. ASHRAF MALEK
172 doctors shared insights

Enlarged Liver (Definition)

Hepatomegaly, otherwise known as an enlarged liver, is a clinical finding in which the liver is found to be larger than is normal, either by the physical exam from a physician or by imaging such as CT scan or ultrasound. This can be due to alcoholism, hepatitis viruses, inherited liver ...Read more


Enzyme (Definition)

An enzyme causes the transformation of a compoond to another compound. In living structures, it is the transformation of a protein to another form. An example is from an inactive state ...Read more