Doctor insights on:
Endometrial Stromal Sarcoma
By definition, it is malignant (i.e., being locally invasive and at least theoreticlally capable of metastasizing), and arises from / mimics muscle or connective tissue elements that are not marrow or immune / white cells. The sarcomas are a tremendously varied and troublesome family of tumors, though thankfully less common than carcinomas and the leukemia / ...Read more
What does this mean?Endometrial biopsy:benign proliferative endometrium with ciliated cell metaplasia without
hyperplasia or malignancy
Normal : It's benign tissue that shows estrogen effect (proliferative endometrium), cell changes that are benign (ciliated metaplasia) & no precancerous or cancerous cells. It's normal and usually means you can avoid major surgery if you have bleeding. Consider hormonal management or an ablation if you have bleeding problems. Take care. ...Read more
Histological section shows mainly decidualised endometrial tissue with hyperplastic glandular component
specimen: uterine evacuation?
Hyperplasia: The sample you describe is suggestive of overgrowth of tissue in the uterus due to irregular menstrual cycles. It is seen in women who go for > 6 months without bleeding and suggests overstimulation due to estrogen effect. If left untreated, it could lead to endometrial cancer. Still, it is very slow growing but needs to be monitored. ...Read more
Uterine wall- non secretory surface endometrium over myometrium. Uterine nodule - leiomyoma of uterus without cellular atypia. Uterine cervix- chro?
Assuming the polyp: Was removed and "simple cystic hyperplasia" is the final diagnosis in the pathology report, then yes, it is benign. The pathology report needs to be understood in its entirety. It is also important to follow up with your doctor regarding the need for any further workup, if necessary. ...Read more
Colon biopsy:huge tubulovillous adenoma with marked atypia, multi foci adenocarcinoma in situ &one tiny focus suggestive of micro invasion.Is it cancer?
2specs: mesothelial-lined tissu w/endometrial-like stroma: 1 stain: cd10positiv in stroma; 2: calretinin&d2-40 postv in mesoth. Cells. Poss malignant?
Tumor markers: An answer to your question isn't possible on-line. This needs to be discussed with the doctor ordering the test and the doctor interpreting the results. More details of you history and reasons for the testing are needed. It's not possible in this situation to tell you more. ...Read more
Generally no.: Endometrial cells can be 'normal' in a pap test depending upon the age of the patient and the time of the menstrual cycle in which the test was performed. If a pap is collected in a premenopausal woman within 10 days of the onset of bleeding / menses, then the endometrial cells are most likely part of uterine shedding. In postmenopausal women, a finding of endometrial cells needs explanation. ...Read more
Usually not: "cystic degeneration" usually means that a portion of the tumor has died as a result of its blood supply not always being adequate. If the tumor is troubling you, or if it is growing rapidly, or the radiologist has other concerns, you should consider having it removed or you may be given other options such as embolization. If there are other warnings of cancer, you must have it removed. Good luck. ...Read more
Unfortunate: This is usually an unfortunate situation. The most common primary site will be somewhere in the intestinal tract, like the stomach. The pathologists will try many stains on the tissue to help define the origin. This helps with choosing the most appropriate chemotherapy. ...Read moreSee 1 more doctor answer
Invasive non keratinizing squamous cell carcinoma tongue showing nests of malignant squamous cells grade 3 prognosis?
Can be cured: If no nodes palpable and lesion localized, RT chemo can reduce size and position site for curative resection. Partial glossectomy after initial therapy. If larger and not responsive to chemo, Ive used hight dose MTX with citrovorum factor over 12 hrs. Most effective in presence of nodal disease Basic chemo is Platinum/Taxol + RT ...Read more
Mesothelioma biopsy says 'portions of fibrous tissue infiltrated by malignant cells forming nests. tumor cells +'ve for CK7 and calretinin. prognosis?
Marker not prognosis: CK7 and calretinin are used to verify that the tumor is mesothelial in origin (versus adenocarcinoma of the lung). It does not provide information about prognosis. Factors associated with pleural mesothelioma prognosis include: functional status, blood counts, histology (epithelial best vs fibrosarcomatous poorest), and tumor size (degree of involvement of pleural cavity). Several new trials. ...Read more
Pathology report states: Postmenapausal Weakly-proliferative endometrium with focal glandular crowding. Focal mucinous metaplasia. Is this something t?
Excess estrogen : This is suggestive of an increased estrogen state and maybe be a precursor to endometrial hyperplasia. alternatively it may be a component of a polyp. If you are in hormone supplements or tamoxifen you should consider stopping them. It warrants follow up with periodic re biopsy yo make sure nothing else is brewing. The good news is they didn't see any tumor. ...Read more
Chronic non specific cervicitis with squamous hyperplasia, squamous metaplasia + focal ciliated tubal endometrial metaplasia. Cause and treatment?
Are uterine cancer, endometrial / ovarian cancer, and uterine fibroids/other abnormalities detected through pap smear other than cervical cancer?
No.: Pap smears sample cervical cells only.Get a more detailed answer ›
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