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Doctor insights on: Endometrial Stromal Sarcoma

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Endometrial sqamous metaplastic cells?

Endometrial sqamous metaplastic cells?

Benign change: This not a cancer or pre-cancer but a benign, that is inconsequential finding. ...Read more

Dr. Suzanne Galli
2 doctors shared insights

Sarcoma (Definition)

By definition, it is malignant (i.e., being locally invasive and at least theoreticlally capable of metastasizing), and arises from / mimics muscle or connective tissue elements that are not marrow or immune / white cells. The sarcomas are a tremendously varied and troublesome family of tumors, though thankfully less common than carcinomas and the leukemia / ...Read more


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Endometrial sqamous metaplastic cells endo biopsy has been done?

Endometrial sqamous metaplastic cells endo biopsy  has been done?

Please clarify: Pap smears and biopsies often show both squamous metaplastic endocervical cels and endometrial cells. Beyond a heads-up that hpv may be present, squamous metaplasia isn't a great concern. If you can rephrase what you are asking, someone here will be glad to help. ...Read more

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What does this mean?Endometrial biopsy:benign proliferative endometrium with ciliated cell metaplasia without hyperplasia or malignancy

What does this mean?Endometrial biopsy:benign proliferative endometrium with ciliated cell metaplasia without
hyperplasia or malignancy

Normal : It's benign tissue that shows estrogen effect (proliferative endometrium), cell changes that are benign (ciliated metaplasia) & no precancerous or cancerous cells. It's normal and usually means you can avoid major surgery if you have bleeding. Consider hormonal management or an ablation if you have bleeding problems. Take care. ...Read more

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Histological section shows mainly decidualised endometrial tissue with hyperplastic glandular component specimen: uterine evacuation?

Histological section shows mainly decidualised endometrial tissue with hyperplastic glandular component

specimen: uterine evacuation?

Hyperplasia: The sample you describe is suggestive of overgrowth of tissue in the uterus due to irregular menstrual cycles. It is seen in women who go for > 6 months without bleeding and suggests overstimulation due to estrogen effect. If left untreated, it could lead to endometrial cancer. Still, it is very slow growing but needs to be monitored. ...Read more

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Uterine wall- non secretory surface endometrium over myometrium. Uterine nodule - leiomyoma of uterus without cellular atypia. Uterine cervix- chro?

Uterine wall- non secretory surface endometrium over myometrium.   Uterine nodule -  leiomyoma of uterus without cellular atypia. Uterine cervix- chro?

Path report: Is this a biopsy? Are you bleeding? Results of a hysteroscopic procedure? Go to the post procedure follow up and discuss the next step with your gyn physician. ...Read more

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Endometrial polyp? Simple cystic hyperplasia, endometrium. Is it cancerous?

Endometrial polyp?  Simple cystic hyperplasia, endometrium. Is it cancerous?

Assuming the polyp: Was removed and "simple cystic hyperplasia" is the final diagnosis in the pathology report, then yes, it is benign. The pathology report needs to be understood in its entirety. It is also important to follow up with your doctor regarding the need for any further workup, if necessary. ...Read more

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What is differentiated adenocarcinoma endometrium?

What is differentiated adenocarcinoma endometrium?

Cancer of the uterus: This is a medical expression used when doctors report a diagnosis of Cancer of the Uterus lining(endometrium). Your gynecologist can explain further, so call him/her up ASAP and ask how to get this disease treated soon. ...Read more

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Colon biopsy:huge tubulovillous adenoma with marked atypia, multi foci adenocarcinoma in situ &one tiny focus suggestive of micro invasion.Is it cancer?

Colon biopsy:huge tubulovillous adenoma with marked atypia, multi foci adenocarcinoma in situ &one tiny focus suggestive of micro invasion.Is it cancer?

Yes: Adenocarcinoma in situ is cancer. The area suggestive of micro invasion suggests you should have rather aggressive followup screening which I am sure your doctor has, or will soon suggest. Stay on top of this and follow his/her advice. ...Read more

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2specs: mesothelial-lined tissu w/endometrial-like stroma: 1 stain: cd10positiv in stroma; 2: calretinin&d2-40 postv in mesoth. Cells. Poss malignant?

2specs: mesothelial-lined tissu w/endometrial-like stroma: 1 stain: cd10positiv in stroma; 2: calretinin&d2-40 postv in mesoth. Cells. Poss malignant?

Tumor markers: An answer to your question isn't possible on-line. This needs to be discussed with the doctor ordering the test and the doctor interpreting the results. More details of you history and reasons for the testing are needed. It's not possible in this situation to tell you more. ...Read more

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Endometrial cells on pap means cancer?

Endometrial cells on pap means cancer?

Generally no.: Endometrial cells can be 'normal' in a pap test depending upon the age of the patient and the time of the menstrual cycle in which the test was performed. If a pap is collected in a premenopausal woman within 10 days of the onset of bleeding / menses, then the endometrial cells are most likely part of uterine shedding. In postmenopausal women, a finding of endometrial cells needs explanation. ...Read more

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Is uterine fibroid with cystic degeneration cancerous?

Is uterine fibroid with cystic degeneration cancerous?

Usually not: "cystic degeneration" usually means that a portion of the tumor has died as a result of its blood supply not always being adequate. If the tumor is troubling you, or if it is growing rapidly, or the radiologist has other concerns, you should consider having it removed or you may be given other options such as embolization. If there are other warnings of cancer, you must have it removed. Good luck. ...Read more

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Metastatic carcinoma omental tissue with unknown source men?

Metastatic carcinoma omental tissue with unknown source men?

Unfortunate: This is usually an unfortunate situation. The most common primary site will be somewhere in the intestinal tract, like the stomach. The pathologists will try many stains on the tissue to help define the origin. This helps with choosing the most appropriate chemotherapy. ...Read more

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Invasive non keratinizing squamous cell carcinoma tongue showing nests of malignant squamous cells grade 3 prognosis?

Invasive non keratinizing squamous cell carcinoma tongue showing nests of malignant squamous cells grade 3 prognosis?

Can be cured: If no nodes palpable and lesion localized, RT chemo can reduce size and position site for curative resection. Partial glossectomy after initial therapy. If larger and not responsive to chemo, Ive used hight dose MTX with citrovorum factor over 12 hrs. Most effective in presence of nodal disease Basic chemo is Platinum/Taxol + RT ...Read more

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Mesothelioma biopsy says 'portions of fibrous tissue infiltrated by malignant cells forming nests. tumor cells +'ve for CK7 and calretinin. prognosis?

Mesothelioma biopsy says 'portions of fibrous tissue infiltrated by malignant cells forming nests. tumor cells +'ve for CK7 and calretinin. prognosis?

Marker not prognosis: CK7 and calretinin are used to verify that the tumor is mesothelial in origin (versus adenocarcinoma of the lung). It does not provide information about prognosis. Factors associated with pleural mesothelioma prognosis include: functional status, blood counts, histology (epithelial best vs fibrosarcomatous poorest), and tumor size (degree of involvement of pleural cavity). Several new trials. ...Read more

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Pathology report states: Postmenapausal Weakly-proliferative endometrium with focal glandular crowding. Focal mucinous metaplasia. Is this something t?

Pathology report states: Postmenapausal Weakly-proliferative endometrium with focal glandular crowding. Focal mucinous metaplasia. Is this something t?

Excess estrogen : This is suggestive of an increased estrogen state and maybe be a precursor to endometrial hyperplasia. alternatively it may be a component of a polyp. If you are in hormone supplements or tamoxifen you should consider stopping them. It warrants follow up with periodic re biopsy yo make sure nothing else is brewing. The good news is they didn't see any tumor. ...Read more

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Chronic non specific cervicitis with squamous hyperplasia, squamous metaplasia + focal ciliated tubal endometrial metaplasia. Cause and treatment?

Chronic non specific cervicitis with squamous hyperplasia, squamous metaplasia + focal ciliated tubal endometrial metaplasia. Cause and treatment?

Consult you GYN MD: This may be a pap report or biopsy and you don't say which. You need to consult your treating GYN MD who performed the test for your answers. ...Read more

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Are carcinoid tumors carcinoma? Is malignant metastatic stomach carcinoma that's hereditary a carcinoid cancer? carcinoid Neuroendocrine tumors?

Are carcinoid tumors carcinoma? Is malignant metastatic stomach carcinoma that's hereditary a carcinoid cancer? carcinoid Neuroendocrine tumors?

Complicated question: Carcinoids are carcinomas, usually more slow growing than adenocarcinomas. For information in this topic you may consult this link: http://www.webmd.com/cancer/carcinoid-tumors#1 ...Read more