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Doctor insights on: Endometrial Biopsy Procedure Note

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How is endometrial biopsy done? Can this procedure confirm presence of abnormal cells or a surgery/operation is required to check for abnormal cells?

How is endometrial biopsy done? Can this procedure confirm presence of abnormal cells or a surgery/operation is required to check for abnormal cells?

Uterine sample: Usually an endometrial biopsy is completed in the office by inserting a small catheter/tube through your cervix and into the uterus. This takes a sample of tissue from the lining of the uterus. It can evaluate the presence of normal or abnormal cells in the uterus.
A surgical procedure (D&C) may be necessary if unable to do an office biopsy. ...Read more

Dr. Sandra Lora Cremers
2 Doctors shared insights

Biopsy (Definition)

Biopsy is tissue removed by needle or cutting to remove part of a body part. It is usually a small amount of material that is processed by a pathologist. Most of the time it is stained and looked at through a microscope to arrive at a diagnosis. Special processes are done for some tissues or problems. The purpose is to tell what the problem is (diagnosis). ...Read more


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Is endometrial biopsy a very painful procedure? Was told once I have a narrower cervix. Stories online are causing me much panic & sleepiness nights.

Relax: Please relax! Most women do fine with endometrial biopsy. The doctor inserts a very thin 3mm straw like pipe into your uterus to obtain some tissue. It is true that you might have pain and discomfort and cramps, but if you relax and breathe the actual insertion part takes only a minute or two. Take 800mg ibuprofen and 1000mg acetaminophen an hour before procedure if not allergic to them. ...Read more

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[contd from q re: 60 year old to have endometrial biopsy] I have never had symptoms of uterine problems (bleeding, cramps, pain, etc). Why is this procedure being performed? My last pap was normal.

Why would: U let your doc do a procedure without asking him or her why? I do not know any doc who would do that without a reason! In my pts the reason I would do it and I would tell them the reason before hand, would be post menopausal bleeding, or too thick endometrium on a pelvic ultrasound, or endometrial cells seen on a pap, but my pt would know why and have the choice to refuse the bx. ...Read more

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55 yow, history of complex partial seizures, postmenopausal, endometrial biopsy neg, day hosp. Hysteroscope D&C scheduled, could this procedure trigger a seizure?

55 yow, history of complex partial seizures, postmenopausal, endometrial biopsy neg, day hosp. Hysteroscope D&C scheduled, could this procedure trigger a seizure?

Unlikely: But, if your complex partial seizures are not well controlled, and your medications are placed on hold for the procedure, then you do have increased risks. Maybe receive your meds that day via intravenous route. ...Read more

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What is endometrial biopsy?

Inside lining of the: Generally, in women over age 35 who have an increase in overall bleeding, the inside lining of the uterus is sampled to ensure its not uterine cancer. This is different from cervical cancer checked by pap. It involed inserting a tube with a suction device or brush in an an exam similar to a pap. It can make you cramp so take 2 aleve (naproxen) if u can. Don't worry, alot of biopsies and find few cancers. ...Read more

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Who need a endometrial biopsy?

Endometrial Biopsy: Generally, an endometrial biopsy is indicated for peri menopausal women who experience dysfunctional uterine bleeding that fails to respond to medical treatment. Your doctor will also order an ultrasound to take a look at the uterus. ...Read more

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How dangerous is an endometrial biopsy?

How dangerous is an endometrial biopsy?

Minor: There are two types: a curettage and a biopsy. The lining of the endometrium is sample through the vagin and cervix. You usually don't feel anything as there are no nerves in the endometrium. Rarely, perforation through the uterus wall may occur, but this is an exceedingly uncommon and unlikely scenario. ...Read more

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How long dies an endometrial biopsy hurt?

Cramps.: Some Motrin before the biopsy prevents the pain for the 6 hours that some people cramp. ...Read more

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What if my endometrial biopsy is abnormal?

What if my endometrial biopsy is abnormal?

Treatment: Abnormal biopsy could be revealing inflammation, hyperplasia or neoplasia of endometrium.
Sometimes, endometrial biopsy fragments can show stromal tissue changes, suggestive leiomyoma (benign tumor).
Ob-gyn physician follow up recomended.
Thank you for question. ...Read more

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What is done during an endometrial biopsy?

Endometrial biopsy: An endometrial biopsy starts just like a Pap smear. A speculum is inserted an the cervix is visualized. The cervix is cleaned off, then a tiny tube is inserted through the cervix into the uterus to get a tiny bit of tissue. It takes about 5 seconds once the tube is inserted. There is normally some cramping during the procedure. The cells are then sent to pathology for evaluation. ...Read more

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What will an endometrial biopsy feel like?

What will an endometrial biopsy feel like?

Cramping: The procedure is variably uncomfortable for different patients, but generally quite tolerable. Some patients may have some discomfort or cramping, during or several hours later, and may have some vaginally spotting. However, most effects are mild and very temporary. ...Read more

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What can you find out with an endometrial biopsy?

Much: It can determine many things including precancerous and cancerous tissue, fertility status, and reasons for heavy or irregular bleeding. ...Read more

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How common is it for someone to need an endometrial biopsy?

Biopsy: Endometrial biopsy is an office procedure to determine a possible cause of a woman's irregular or a heavy period. It is usually done in an office and do not require anesthesia. If your doctor wants to rule out a possible malignant process, a biopsy is usually done. ...Read more

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How much tissue is actually removed in an endometrial biopsy?

How much tissue is actually removed in an endometrial biopsy?

Not much but enough: Very little tissue is removed during an endometrial biopsy but multiple studies show that the amount is adequate to make an accurate diagnosis. The main purpose is to rule out cancer or premalignant lesions called endometrial hyperplasia. ...Read more

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Is it normal to have pain 5 days after an endometrial biopsy?

Is it normal to have pain 5 days after an endometrial biopsy?

Yes, it can be: Cramping can be caused by the uterus contracting. You can take Ibuprofen to get some relief. You can even have some bleeding or spotting. ...Read more

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What is the definition or description of: endometrial biopsy?

What is the definition or description of: endometrial biopsy?

Diagnostic biopsy: Endometrial biopsy: a common procedure for sampling the inner lining of the uterus (the endometrium). ...Read more

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I'm having an endometrial biopsy & looking for relief from pain?

Endometrial biopsy: This produces minimal discomfort you should not need pain medication. Procedure is quite simple. ...Read more

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What are the signs that you should get a endometrial biopsy done?

Endometrial biopsy: Endometrial biopsy is performed for abnormal uterine bleeding in anyone over 40-45. If younger than an endometrial biopsy is performed for persistent abnormal uterine bleeding or any abnormal uterine bleeding in the face of risk factors such as obesity or family history. If not menopausal than a pregnancy test should be performed first. ...Read more

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How long does an endometrial biopsy take and how should I prepare?

Good luck: Prepare like you would as if going to your gyn for a routine exam. Listen to any specific instructions from the gyn dr. As instructed, for example, they may have told you to stop Aspirin or Ibuprofen if you are taking those to decrease bleeding, etc. The whole procedure may only take 15 minutes or there about. Preparation and paper work, etc, may be an hour or so. Best wishes. ...Read more

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What is the process of an endometrial biopsy and how does it feel?

Like a pap smear: First a speculum is placed just like for a pap smear. Then the cervix is cleansed with betadine. Next an instrument is placed on the cervix that may cause a menstrual like cramp. Then you may feel some tugging on the cervix while a small catheter is placed inside the cavity of the uterus. This feels like another stronger and sharper menstrual cramp but lasts less than 15 seconds. ...Read more

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Could you tell me what happens if my endometrial biopsy is abnormal?

Ask your GYN doc: It really depends on the exact cause of the abnormality. For instance, endometrial cancer requires different treatment from mild inflammation. You need to speak with your gyn doc for the answer to your question. ...Read more

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How long will it take to get the results back from an endometrial biopsy?

How long will it take to get the results back from an endometrial biopsy?

Depends on lab: Most pathology laboratories have a 2-3 day turn around time. However, timing factors and special studies can increase the time to results. To improve your chances of a quick turn-around time, schedule your biopsy early in the day and early in the week. Consider requesting that your biopsy be reviewed by a specialist in gynecologic pathology, although this can take longer to arrange. ...Read more

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If I need to have an endometrial biopsy performed how should I prepare for it?

Nothing: Endometrial biopsies do not require any preparation. Ask your doctor, but use of an anti-inflammatory medications, such as aleve, (naproxen) can help with any cramping that might occur after the biopsy - this cramping is usually similar to menstrual cramps and is short lived. ...Read more

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How long does it usually take to get the results back from an endometrial biopsy?

Depends on lab: Using one of the big labs like quest or labcorp results should be available in 48 hours. ...Read more

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Diagnosis on my endometrial biopsy states: no tissue recovered after routine processing. What does that mean?

See below: The biopsy did not recover enough tissue for processing for microscopic examination. Your endometrium may be so atrophic that it did not yield tissue on biopsy or it may have been a technical problem. Please discuss the matter with your doctor to see if an other attempt at biopsy is warranted. ...Read more

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How painful is an endometrial biopsy? I've read stories about women passing out, going into shock, etc. Any truth to those claims? I'm so scared

Discomfort: Different people react differently to the discomfort of dilatation of the cervix that is needed to pass the instrument through the canal. The biopsy per se should not be that painful. Express your concern to your doctor to ensure you have adequate pain medication and if needed, be under moderate sedation. ...Read more

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Had endometrial biopsy around 12 this afternoon sent to quest. Approx. How long to get results and if bad do they make it priority and tell dr early?

Time: If we consider legality, it is mandated that abnormal results be notified to physician? It is his priority to notify you, the pt. Some tests do take time if complex. Talk to your dr. If delay. ...Read more

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Is it possible to have an endometrial biopsy while menstrating?

Is it possible to have an endometrial biopsy while menstrating?

Yes, but...: It is possible, but your doctor is more likely to just get blood. Discuss it with your doctor. ...Read more

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Will having an endometrial biopsy break my hymen?

Unlikely: An endometrial biopsy requires placing a speculum in the vagina. For a virginal woman, it can sometimes be accomplished without disturbing an intact hymen with a very narrow speculum. Many women of the age that would necessitate a biopsy however do not have a narrow intact hymen even if they are virginal. ...Read more

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How long will I bleed for after an endometrial biopsy?

How long will I bleed for after an endometrial biopsy?

No bleeding: Endometrial biopsy can be performed not only for diagnostic evaluation of tissue, but as treatment to stop endometrial bleeding. If you bleeding for few days, please see your doctor. ...Read more

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Why am I still bleeding days after an endometrial biopsy?

Why am I still bleeding days after an endometrial biopsy?

ToBleedOrNotToBleed: Some light spotting for a few days is not unusual, but if it persists for over a week, especially if increasing in amount or accompanied by pain, foul odor or fever then you should see your doctor ASAP. Now, at your age, having the biopsy is a bit unusual so maybe the reason your doctor got the biopsy is the reason for the prolonged bleed (e.g.friable tissue)but in any case, your doctor should know ...Read more

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Do I panic had endometrial biopsy friday results not back yet?

Never panic: Panic isn't helpful. Most of the time the biopsy will return benign and you and your doctor can discuss management options for abnormal bleeding. Biopsy results are typically finalized within a few days-- you can call your office to see if they are back. ...Read more

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When should an endometrial biopsy be done for abnormal bleeding?

When should an endometrial biopsy be done for abnormal bleeding?

If it is unexplained.: If the cause of abnormal bleeding cannot be explained, especially in women over 40, and definitely in all postmenopausal women, an endometrial biopsy should be done to rule out a cancer of the uterus. An endometrial biopsy will take a sampling of cells from inside the uterine cavity that can be sent to a pathologist to look for abnormal cells or hormone imbalances. ...Read more

Dr. Deepali Kashyap
164 Doctors shared insights

Endometrial Biopsy (Definition)

Endometrial biopsy: a common procedure for sampling the inner lining of ...Read more