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Doctor insights on: Endometrial Biopsy Cause Elevated Ca 125

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What could be the cause of my thick endometrial lining ( 21mm on CD 11) ? My endometrial biopsy results were normal and all hormone testing is normal.

What could be the cause of my thick endometrial lining ( 21mm on CD 11) ? My endometrial biopsy results were normal and all hormone testing is normal.

Endometrium: The uterine lining may keep growing in response to estrogen. It can occur in PCOS, obesity, taking medications that increase estrogen levels. It is good that you are getting evaluated for it. ...Read more

Dr. Erik Borncamp
2 doctors shared insights

Biopsy (Definition)

Biopsy is tissue removed by needle or cutting to remove part of a body part. It is usually a small amount of material that is processed by a pathologist. Most of the time it is stained and looked at through a microscope to arrive at a diagnosis. Special processes are done for some tissues or problems. The purpose is to tell what the problem is (diagnosis). ...Read more


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How much tissue is actually removed in an endometrial biopsy?

How much tissue is actually removed in an endometrial biopsy?

Not much but enough: Very little tissue is removed during an endometrial biopsy but multiple studies show that the amount is adequate to make an accurate diagnosis. The main purpose is to rule out cancer or premalignant lesions called endometrial hyperplasia. ...Read more

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Will having an endometrial biopsy break my hymen?

Unlikely: An endometrial biopsy requires placing a speculum in the vagina. For a virginal woman, it can sometimes be accomplished without disturbing an intact hymen with a very narrow speculum. Many women of the age that would necessitate a biopsy however do not have a narrow intact hymen even if they are virginal. ...Read more

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I have a fishy smelling discharge after an endometrial biopsy, should I be concerned?

I have a fishy smelling discharge after an endometrial biopsy, should I be concerned?

Possibly: Any abnormal discharge after an endometrial biopsy should be reported to your doctor, as it may be a symptom of having an infection of the uterus. It sounds like there is a just a bacterial overgrowth, called bacterial vaginosis. Antibiotics and probiotics can help treat and prevent "bv." see your doctor to be sure. ...Read more

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I am having an endometrial biopsy by brushing. What does this mean?

I am having an endometrial biopsy by brushing. What does this mean?

Not sure: An endometrial biopsy can be preformed by placing a small cannula inside the uterus and taking a sample. The tube is takes a sample as it is pulled in a circular in and out motion along the lining of the uterus which is the endometrium. It applies a gentle suction to collect the sample, . ...Read more

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Why would my doctor prefer an endometrial biopsy?

More info?: Typically we like to do the one procedure that will give us the most complete information. ...Read more

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Doctor ordered endometrial biopsy, should I be worry?

Doctor ordered endometrial biopsy, should I be worry?

No always worrysome: If doctor ordered endometrial biopsy, he/she wants to understand the cause of your symptoms and you have appropriate treatment. It does not mean you have abnormal result. Be strong and follow doctor's instructions. ...Read more

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How long does cramping last after my endometrial biopsy?

A few hours: Cramping should only last a few hours at most. This also depends on if your cervix needs to be dilated in order to obtain the biopsy. Taking an anti-inflammatory medication prior to the procedure may also help reduce cramping. ...Read more

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Can doctors do an endometrial biopsy when you have period?

Yes: There are a few exceptions for infertility cases but for the most part it does not matter if you are still bleeding at the time of endometrial biopsy. In fact, the cervicl os or opening of the cervix is more open than usual making the biopsy slightly easier. ...Read more

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How long will i bleed after an endometrial biopsy and colposcopy?

How long will i bleed after an endometrial biopsy and colposcopy?

May be a couple of: Days. Most biopsy sites should not bleed for more that a day or two. However, spotting may last longer depending on the reason for the biopsy. It would be prudent to ask your doctor who has more information about your health. ...Read more

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What does it mean when the doctor sends you for an endometrial biopsy?

Varies: It would depend on what symptoms you had. Endometrial biopsy may be done to investigate fertility, assess precancerous and suspected cancerous lesions. ...Read more

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After having an endometrial biopsy, how long do I need to wait to have sex?

After having an endometrial biopsy, how long do I need to wait to have sex?

1 week: Your doctor should have gone over this with you....But typically the rule is one week from most procedures, including endometrial biopsies. ...Read more

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I am 40 recently had endometrial biopsy with report says proliferative endometrium with fibrinous what does this mean?

Endometrial 2 phases: The endometrium(lining of the womb) grows in two phases. The first half of the cycle it is "proliferative" in response to estrogen. the second half of the cycle post ovulation is "secretory", normally. A biopsy was take due to concerns for cancer and your report shows "estrogen only" phase stimulation. At age 40 your MD may add progesterone to decrease the risk of endometrial cancer. ...Read more

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Dr. Bernard Seif
125 doctors shared insights

Ca125 (Definition)

Ca-125 (cancer antigen 125 or carbohydrate antigen 125) is a biomarker/tumor marker for ovarian cancer (etc); however, it is not sensitive or specific enough to use as a screening test. Also, a uk study showed that treating based on ca125 level did not improve outcomes. "125" comes from the 125th attempt to develop a marker. It was introduced by bast ...Read more


Dr. Deepali Kashyap
161 doctors shared insights

Endometrial Biopsy (Definition)

Endometrial biopsy: a common procedure for sampling the inner lining of ...Read more