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Doctor insights on: Endometrial Biopsy Cause Elevated Ca 125

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Dr. Michael Kleerekoper
2 doctors shared insights

Biopsy (Definition)

Biopsy is tissue removed by needle or cutting to remove part of a body part. It is usually a small amount of material that is processed by a pathologist. Most of the time it is stained and looked at through a microscope to arrive at a diagnosis. Special processes are done for some tissues or problems. The purpose is to tell what the problem is (diagnosis). ...Read more


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How much tissue is actually removed in an endometrial biopsy?

How much tissue is actually removed in an endometrial biopsy?

Not much but enough: Very little tissue is removed during an endometrial biopsy but multiple studies show that the amount is adequate to make an accurate diagnosis. The main purpose is to rule out cancer or premalignant lesions called endometrial hyperplasia. ...Read more

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Will having an endometrial biopsy break my hymen?

Unlikely: An endometrial biopsy requires placing a speculum in the vagina. For a virginal woman, it can sometimes be accomplished without disturbing an intact hymen with a very narrow speculum. Many women of the age that would necessitate a biopsy however do not have a narrow intact hymen even if they are virginal. ...Read more

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I have a fishy smelling discharge after an endometrial biopsy, should I be concerned?

I have a fishy smelling discharge after an endometrial biopsy, should I be concerned?

Possibly: Any abnormal discharge after an endometrial biopsy should be reported to your doctor, as it may be a symptom of having an infection of the uterus. It sounds like there is a just a bacterial overgrowth, called bacterial vaginosis. Antibiotics and probiotics can help treat and prevent "bv." see your doctor to be sure. ...Read more

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I am having an endometrial biopsy by brushing. What does this mean?

Not sure: An endometrial biopsy can be preformed by placing a small cannula inside the uterus and taking a sample. The tube is takes a sample as it is pulled in a circular in and out motion along the lining of the uterus which is the endometrium. It applies a gentle suction to collect the sample, . ...Read more

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Why would my doctor prefer an endometrial biopsy?

More info?: Typically we like to do the one procedure that will give us the most complete information. ...Read more

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Doctor ordered endometrial biopsy, should I be worry?

Doctor ordered endometrial biopsy, should I be worry?

No always worrysome: If doctor ordered endometrial biopsy, he/she wants to understand the cause of your symptoms and you have appropriate treatment. It does not mean you have abnormal result. Be strong and follow doctor's instructions. ...Read more

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How long does cramping last after my endometrial biopsy?

A few hours: Cramping should only last a few hours at most. This also depends on if your cervix needs to be dilated in order to obtain the biopsy. Taking an anti-inflammatory medication prior to the procedure may also help reduce cramping. ...Read more

Dr. Jeffrey Wint
125 doctors shared insights

Ca125 (Definition)

Ca-125 (cancer antigen 125 or carbohydrate antigen 125) is a biomarker/tumor marker for ovarian cancer (etc); however, it is not sensitive or specific enough to use as a screening test. Also, a uk study showed that treating based on ca125 level did not improve outcomes. "125" comes from the 125th attempt to develop a marker. It was introduced by bast ...Read more


Dr. Deepali Kashyap
155 doctors shared insights

Endometrial Biopsy (Definition)

Endometrial biopsy: a common procedure for sampling the inner lining of ...Read more