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Doctor insights on: Endocrine Pancreatic Insufficiency

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What is primary adrenal insufficiency (addisons disease)?

What is primary adrenal insufficiency (addisons disease)?

Adrenal cortex: The adrenal cortex makes lots of hormones. Very important are cortisol and aldosterone which help maintain life and salt balance. Addison's disease is caused by adrenal cortex damage rendering it unable to make these hormones anymore, mostly autoimmune cause in us. Patients often have a bronzed look. Hydrocortisone replacement is a lifesaving necessity. Fludrocortisone may also become necessary. ...Read more

Dr. Mark Pack
3 doctors shared insights

Pancreas (Definition)

Abdominal organ. It is digestive organ: it secretes enzymes into the small bowel which break down food and help its absorption. It is also an endocrine organ: it produces hormones involved in sugar control and control of digestion. Insulin is one of these hormones. Diabetics either lack Insulin (type 1 diabetes) or have inadequate ...Read more


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Is adrenal insufficiency hereditary?

Is adrenal insufficiency hereditary?

It can be.: One cause of adrenal insufficiency, addison's disease, is an auto-immune disorder. The immune system mistakenly makes antibodies targeting one or more proteins in the adrenal cortex, and winds up destroying the adrenal cortex, so that the adrenals can no longer make cortisol, or other hormones. As is true for most auto-immune disorders, a tendency to develop addison's can run in families. ...Read more

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What causes adrenal insufficiency?

What causes adrenal insufficiency?

Multiple causes: Infections of the gland by bacteria, including meningococcus and tb, metastatic tumors and primary tumors of adrenals, metabolic disorders, e.g., congenital adrenal hyperplasia, lack of pituitary stimulation, amyloid infiltration and sudden stoppage of steroid treatment etc. ...Read more

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Is central diabetes insipidus related to adrenal insuffiency? Im having an ACTH test to check adrenal function.

Is central diabetes insipidus related to adrenal insuffiency? Im having an ACTH test to check adrenal function.

Can be: Hi. If you have Addison's (skin, crease, gum, and scar darkening, malaise, nausea, dizziness, vital signs abnormalities, electrolyte abnormalities, etc), your ACTH will be very high. Addison's is most commonly an autoimmune disease. At least a subset of idiopathic central DI appears to be autoimmune in nature, and the risk of that goes up with other autoimmune diseases. If real, you got 2 rare 1's ...Read more

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Can cryofibrinogenemia cause partial adrenal insufficiency?

Can cryofibrinogenemia cause partial adrenal insufficiency?

Theoretically yes: Cryofibrinogenemia increases your risk of arterial and venous clots. Antiphospholipid syndrome does the same thing, and is associated in rare cases with primary adrenal insufficiency. So it's theoretically possible that the same mechanism could cause adrenal insufficiency in cryofibrinogenemia, by clotting off the blood vessels that supply the adrenal glands. Good question! ...Read more

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Can kidney cysts cause adrenal insufficiency?

Can kidney cysts cause adrenal insufficiency?

No: The adrenal glands, sitting on top of each kidney, are typically preserved in cystic kidney diseases. However that does not exclude screening for ai if clinical features are present such as unexplained hypotension, salt craving or worsening headaches. ...Read more

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Is primary adrenal insufficiency the same as addison's disease?

Often, yes: Addison's disease is an autoimmune disease which harms the cortex of the adrenal glands. However, anything that damages the adrenal cortex can also cause primary adrenal insufficiency. ...Read more

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Do women with addison's adrenal insufficiency have low estrogen ?

Do women with addison's adrenal insufficiency have low estrogen ?

Not significantly: The adrenal glands produce hormones which are precursors to estrogen, but that only comprises a small amount relative to what the ovaries make. Ovaries are the source of most estrogen in females. If menstrual cycles are irregular in properly treated addison's disease, autoimmune disease of the ovaries may need to be considered also. ...Read more

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Can Lyme disease cause adrenal insufficiency?

Lyme disease: There is much speculation, primarily in the lay press about "adrenal exhaustion" due to lyme disease. This seems to be purely theoretical and not based on any firm scientific evidence. The problem is that there is much we do not understand about lyme disease, and it has been the speculative cause of many unexplained illnesses. Stick to "proven" facts, and adrenal insufficiency is not. ...Read more

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Can chronic mesenteric ischemia cause pancreatic insuffiency?

Can chronic mesenteric ischemia cause pancreatic insuffiency?

No.: Chronic mesenteric ischemia (cmi) occurs because of poor blood flow to the intestines, classically needing 2 out of 3 blood vessels to the gut with a significant narrowing. The usual symptoms of cmi are abdominal pain after meals, unintended weight loss, and a "fear of eating." the pancreas has such a rich blood supply that poor blood flow to it is not usually a problem. ...Read more

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Can my heterozygotes status of congenital adrenal hyperplasia (21-Hydrolaxe deficiency, salt-wasting) explain hirsurtism & symptoms like polydipsia?

Can my heterozygotes status of congenital adrenal hyperplasia (21-Hydrolaxe deficiency, salt-wasting) explain hirsurtism & symptoms like polydipsia?

Maybe: Hydroxylase deficiency is actually a continuum, and there are many alleles. A workup is probably not worthwhile. Manage unwanted body hair with electrolysis or lasers -- you're doing yourself a favor. If your urinalysis (chemical, sediment), renal functions (BUN, creatinine) and concentrating ability (SG >1.020) while thirsty) are normal, I would not recommend further studies. ...Read more

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Which test is better for diagnosing pancreas insufficiency: stool panc elastase or serum lipase/amylase? Would either diagnose pancreatic cancer?

Which test is better for diagnosing pancreas insufficiency: stool panc elastase or serum lipase/amylase? Would either diagnose pancreatic cancer?

Both together: Neither of the tests alone tells much. A combination of tests and exams will lead to diagnosis. Pancreatic cancer is not able to be ruled out by any test or imaging study. It can only be absolutely proven by some form of biopsy. A ct guided needle or egd with brushing a may be the only way to find it. ...Read more

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Is primary biliary cirrhosis hereditary?

Is primary biliary cirrhosis hereditary?

Basically no: There's a pair of genes that carry the ability to develop the disease and these run in families, but it's not inherited like sickle cell, huntington's or some of the other familiar entities. http://www.medicalnewstoday.com/releases/151640.php. ...Read more

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Does pancreatictist lead to pancreatic cancer ?

Does pancreatictist lead to pancreatic cancer  ?

Risk factors 2 watch: The risk of pancreatic cancer is increased in: tobacco smokers, being overweight, workplace exposure to certain chemicals, age >45, male gender, Afro American race, family history, genetic syndromes, diabetes, liver cirrhosis, chronic pancreatitis, possibly H.pylori, diets (rich in red meat, pork, processed meats), physical inactivity, heavy alcohol intake. Best to change what risks you can please ...Read more

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Gastroparesis related to hashimoto disease?

Gastroparesis related to hashimoto disease?

It may..: Patients with gastroparesis may usually have underlying diabetes. There are other causes for gastroparesis, including a hypoactive thyroid.It turns out that the most common kind of hypothyroidism is hashimoto's disease, which is an autoimmune disease just like some forms of diabetes!your endocrinologist can definitely provide more info about this. Take care! ...Read more

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Can pancreatic stenting for pancreatic divisum be dangerous?

Can pancreatic stenting for pancreatic divisum be dangerous?

Yes: Any instrumentation during an ERCP can cause acute pancreatitis. But procedures are done when reward>risk. ...Read more

Dr. Tyrone Malloy
267 doctors shared insights

Endocrine System (Definition)

The endocrine system is a group of organs composed of glands that secrete hormones. These hormones have important regulatory functions such as growth, metabolism, ...Read more