Top
40
Doctor insights on: Endocrine Cells Of The Pancreas

Share
Dr. Creighton Wright
3 doctors shared insights

Pancreas (Definition)

Abdominal organ. It is digestive organ: it secretes enzymes into the small bowel which break down food and help its absorption. It is also an endocrine organ: it produces hormones involved in sugar control and control of digestion. Insulin is one of these hormones. Diabetics either lack Insulin (type 1 diabetes) or have inadequate ...Read more


2

2
How can we transplant the beta cells of the pancrease (pancrelipase)?

How can we transplant the beta cells of the pancrease (pancrelipase)?

Work in progress: Islet or beta cell transplant for Insulin production has scientific backing. Check out jdf/juvenile diabetes foundation website 4 links. The enduring problem is not so much the mechanics of the transplant, but preventing autoimmune response from attacking the new cells. In the meantime, if your'e type i, take advantage of amazing technology for management. Pump, sensor, transmitter, amylin. ...Read more

4

4
Is the pancreas part of the digestive system?

Yes: Pancreas is a solid organ that sits behind the stomach. It is an endocrine organ-makes hormones such as insulin-released into the blood stream. It is an exocrine organ-making digestive enzymes released into the upper small intestine via a duct. ...Read more

5

5
Where is the anatomical location of liver enzymes in the hepatocytes?

Where is the anatomical location of liver enzymes in the hepatocytes?

Liver enzymes: Liver enzymes are in the different parts of the organ with no specific anatomic location. Some enzymes are located in the membrane of the hepatocyte, others in the cytoplasm of the hepatocyte and others are in the cells that line the bile ducts. ...Read more

6

6
What enzymes are released by the pancreas into small intestine?

What enzymes are released by the pancreas into small intestine?

Pancreatic enzymes: Broadly, "pancreatic juice" contains many enzymes, including trypsinogen, chymotrypsinogen, elastase, carboxypeptidase, pancreatic lipase, nucleases & amylase. ...Read more

7

7
Which genes control cell growth in pancreatic tissue?

Which genes control cell growth in pancreatic tissue?

There are: literally millions of genes that control cell growth not only in pancreatic tissue but throughout the entire body. Why do you ask? ...Read more

8

8
What's the role of somatic cells in cancer devlopment?

What's the role of somatic cells in cancer devlopment?

Most cancers: Most cancers arise from somatic cells. The change involves a number of steps, though one of the steps may be an inherited defect/mutation. Cells acquire mutations and the ones providing a survival/growth advantage induce proliferation that leads to more mutations. A fully developed cancer has, on average, about 90 mutations. ...Read more

9

9
The dysfunction within what endocrine organ causes diabetes?

The dysfunction within what endocrine organ causes diabetes?

Complex answer: The pancreas is the easy answer, but it's more complex than that. In type i diabetics, it really is an issue with the pancreas. In type ii diabetics, the pancreas generally makes plenty of insulin, but the body becomes resistant to it. Aside from the pancreas, the liver, muscles, and fat are also involved in maintaining normal glucose levels in the body. ...Read more

10

10
What is the role of the liver and pancreas in controlling the blood glucose level?

What is the role of the liver and pancreas in controlling the blood glucose level?

Liver, pancreas, etc: That is an important question but it would be best, at least for now, to go online and look for articles that discuss your issues. There are many articles specifically designed for patients, not doctors. If you have questions after you have read a few articles feel free to send me a question. ...Read more

11

11
Would the invasion of a cell by viruses increase the osmolarity of the cell?

Would the invasion of a cell by viruses increase the osmolarity of the cell?

No: Everything that enters a cell carries with it an amount of water proportionate to the osmotic pull. A virus, being a single particle, in this physical-chemistry scenario, has the same pull as a sodium ion. The permeability of the cell membrane to water is unaffected. ...Read more

12

12
What are the pituitary hormones that stimulate the production of melanin in the body?

What are the pituitary hormones that stimulate the production of melanin in the body?

Melanocytes: Melanin is produced by melanocytes located in your hair, eyes, and skin. It is the pigment that is responsible for skin color. They are not produced by the pituitary. You might be thinking of melatonin which is produced by the pineal gland and is responsible for the modulation of wake/sleep patterns and seasonal functions. I hope this useful. Take care and well wishes. ...Read more

13

13
What specific Autoimmune diseases attack brain cells and neurons causing a dramatic effect to neurotransmitters,hormones and the function of the brain

What specific Autoimmune diseases attack brain cells and neurons causing a dramatic effect to neurotransmitters,hormones and the function of the brain

Lupus: Systemic Lupus can attack everywhere and lead to the things u asked about. Other considerations are vasculitis syndromes as there is an autoimmune attack on and in blood vessels which can affect neurons indirectly. Myasthenia Gravis also affect the neuromuscular system and affects one of the main neurotransmitter, AcetylCholine. Rheumotologist is specialist to see for autoimmune disorders ...Read more

14

14
What is the role of the pancrease (pancrelipase) in controlling the blood glucose level?

What is the role of the pancrease (pancrelipase) in controlling the blood glucose level?

Pancreas & glucose: Pancreatic beta cells secrete Insulin when they detect a rise in blood sugar. Pancreatic Alpha cells produce glucagon which stimulates liver to convert glycogen to glucose (as well as fats & proteins ultimately to glucose) when blood sugar levels are low. ...Read more

15

15
Which organs do the pituitary gland influence?

Which organs do the pituitary gland influence?

Many: Breast, adrenal glands, thyroid glands, ovaries and testes, and kidneys, bones muscles, metabolism of the whole body blood pressure control and others. ...Read more

16

16
Describe the function of the adrenal gland?

Describe the function of the adrenal gland?

Multifunctional: Very briefly, the adrenal gland can be divided between the cortex and medulla. The cortex makes a variety of hormones which control salt balance, cortisol, and androgens. The medulla primarily secretes norepinephrine and epinephrine. Functions of medulla and cortex are completely different as are the way their hormones are made and how they work. ...Read more

18

18
What is the primary function of the endocrine system?

What is the primary function of the endocrine system?

Controls everything: The endocrine system is composed of "ductless" glands that produce various hormones. Thyroid hormone controls the bodies metabolism, adrenal hormone is involved with stress hormones, pituitary hormones control other hormones of the body including reproductive hormones. Insulin is a hormone that controls blood sugar. There are thousands of hormones in the body that control various systems. ...Read more

19

19
What is the gland that secretes both exocrine and endocrine hormone?

What is the gland that secretes both exocrine and endocrine hormone?

Pancreas: Endocrine hormones are secreted into the bloodstream to cause effects in other parts of the body. The pancreas secretes Insulin and glucagon to cause these effects. Exocrine hormones are secreted into body cavities with tubes connecting the producing gland into a body cavity. The pancreas secretes a variety of substances into the intestinal tract. ...Read more

20

20
Can you explain the regulation of adrenal cortex function by the way of the pituitary gland stimulation of the adrena?

Can you explain the regulation of adrenal cortex function by the way of the pituitary gland stimulation of the adrena?

Feedforward/feedback: Hi. Hypothalamus important, but to keep it simple, pituitary ACTH stimulates the adrenal cortex to make cortisol. Cortisol negatively feeds back to suppress pituitary ACTH. If cortisol falls or a big stress is encountered, ACTH goes up and stimulates more cortisol production. The pituitary "sees" the increase in cortisol, and cuts back on ACTH to keep cortisol in appropriate range. Diurnal pattern ...Read more

21

21
Is the pancreas classified under endocrine surgery, gastrointestinal surgery, or another type of surgery?

Is the pancreas classified under endocrine surgery, gastrointestinal surgery, or another type of surgery?

Pancreaticobiliary : most bigger centers have a dedicated team for PBS (pancreaticobiliary surgey). In some cases, a general, gi or onc surgeon can be the one specializing in it as well. ...Read more

22

22
Can you tell me about pancreas, it is both an exocrine and an endocrine gland. however, if you were two classify it one of the categories, in which would you place it?

Pancreas: Can you tell me about pancreas, it is both an exocrine and an endocrine gland. however, if you were two classify it one of the categories, in which would you place it? ANS: it excretes enzymes into the gut and insulin into the blood. So both. If it is sick it could be one or the other only. If not sick then it is both. ...Read more

24

24
I have had appendix cancer that spread & thyroid cancer. My dad had pancreatic cancer. I am curious about men1/2 & endocrine cancers. I'm only 37...?

I have had appendix cancer that spread & thyroid cancer. My dad had pancreatic cancer. I am curious about men1/2 & endocrine cancers. I'm only 37...?

Probably not: Appendix cancer is not part of any men syndrome. Pancreatic cancer can be, but it is a specific type called a neuroendocrine tumor. Likewise, the thyroid cancer in men syndromes is called meduallry carcinoma, which make up only about 10% of all thyroid cancers. ...Read more

See 1 more doctor answer
25

25
What is the difference between endocrine cells and target cells?

What is the difference between endocrine cells and target cells?

Endocrine physiology: I am not sure what you are reading and trying to interpret. But presumably "Endocrine cells" refers to the cells of the endocrine organ itself, whereas "target cells" are the cells of the organ that the hormone goes to. Ex. thyroid hormone is made by thyroid endocrine cells, and circulate in blood and interact with target cells in the heart to increase heart rate. ...Read more

26

26
Since neurosteroids are made by glial cells and not endocrine glands, are they considered hormones? Is there a name for non-gland-produced hormones?

Since neurosteroids are made by glial cells and not endocrine glands, are they considered hormones? Is there a name for non-gland-produced hormones?

Hormones: The terminology has not really caught up to the research. "Hormone" usually refers to a substance that is made in one cell/organ but then influences another organ, like thyroxine or cortisol. Neurosteroids act locally in the synapse on neurotransmission, so not a hormone by usual definition. But there are a lot of substances that act locally (eg. prostaglandins, cytokines). What do we call them? ...Read more

27

27
How can we transplant the beta cells of the pancrease (pancrelipase)?

Work in progress: Islet or beta cell transplant for Insulin production has scientific backing. Check out jdf/juvenile diabetes foundation website 4 links. The enduring problem is not so much the mechanics of the transplant, but preventing autoimmune response from attacking the new cells. In the meantime, if your'e type i, take advantage of amazing technology for management. Pump, sensor, transmitter, amylin. ...Read more

28

28
Hallmark pregnancy symptoms, negative blood test. Pos endocrine issue but bloodwork is normal range, inc w Blood cell count. What could be the problem?

Hallmark pregnancy symptoms, negative blood test. Pos endocrine issue but bloodwork is normal range, inc w Blood cell count. What could be the problem?

I don't understand: your question. There may be no "problem" whatsoever. Women can have symptoms compatible with pregnancy for many reasons other than pregnancy. Since I don't know what your symptoms are, a pregnancy test would be the best way to find out if you're pregnant, and if yours is normal, discuss other potential causes of your symptoms w/your doctor. ...Read more

29

29
How common is a false negative ct when scanning for small cell lung cancer. Weight loss and fatigue present with some endocrine issues.

How common is a false negative ct when scanning for small cell lung cancer.  Weight loss and fatigue present with some endocrine issues.

Very uncommon.: In some respects it depends on how the scan was performed, but, for example, with low dose screening chest CTs, reported sensitivities are generally well above 90%, and in some studies, approach 100% ...Read more

30

30
Are there any artificial pancreases (pancrelipase)?

Are there any artificial pancreases (pancrelipase)?

No: However, transplant of small cellular components of the pancreas which make the insulin, called islets, are done in a few experimental centers around the country. In addition, some patients can do well with an external artificial Insulin pump which delivers Insulin over a two day period and has to be adjusted less frequently than given Insulin shots. ...Read more

See 1 more doctor answer
33

33
What is an endocrine study? How is it done?

What is an  endocrine study? How is it done?

Need more info: Without information as to why an endocrine study was recommended for you, i cannot give you an answer, except to say that most endocrine testing is done through taking a blood sample. ...Read more

34

34
What is endocrine disorder?

What is endocrine disorder?

Hormones: An endocrine disorder is disorder of the endocrine glands which are typically responsible for hormones production/release and regulation. Some examples of endocrine disorders are: disorders of the thyroid, adrenal, pituitary, reproductive system, parathyroid, bone. ...Read more

See 1 more doctor answer
35

35
What is an endocrine gland?

Gland: I may have answered this for you before. Please go online and search for "hormone images". The images should tell you all you need to know about endocrine glands and how they might interact with each other. ...Read more

36

36
What are endocrine system cancers?

What are endocrine system cancers?

Thyroid and ..: Of the endocrine organs, thyroid is the commonest site of cancers. Pituitary tumors while not cancers in the literal sense are still dangerous. Cancers of all endocrine organs are known to occur, e.G, adrenal, parathyroid, pancreatic islets etc. If you include testes and ovaries among the endocrine organs, these two, especially ovary is a common site of cancer. ...Read more

Theresa Yang Dr. Yang
6 doctors agreed:
37

37
How is an endocrine tumor diagnosed?

Theresa Yang Dr. Yang
6 doctors agreed:
How is an endocrine tumor diagnosed?

Combination: A combination of techniques is used to diagnose endocrine tumors. First the patient's symptoms are looked at closely. Lab work is done to verify levels and markers of hormones. Imaging such as mri, ct, ultrasound, or endoscopy can be used to visualize tumor masses. There are dna tests for tumors that are part of a syndrome. ...Read more

See 1 more doctor answer
38

38
What's the cause of neuro endocrine tumors?

Unknown: Like so many other cancers, the cause of neuro-endocrine cancer is unknown. Just consider this to be an accident of nature and accept it as your destiny. ...Read more

Dr. Jennie Law Dr. Law
10 doctors agreed:
39

39
What sort of disorder is an endocrine tumor?

Dr. Jennie Law Dr. Law
10 doctors agreed:
What sort of disorder is an endocrine tumor?

Tumors in hormone: -producing organs, such as the pituitary, thyroid, pancreas, parathyroid, adrenal glands. ...Read more

See 3 more doctor answers
40

40
Can endocrine problems cause osteoarthritis?

Can endocrine problems cause osteoarthritis?

Yes: Hypercortisilinemia can cause osteoarthritis. Hypoparathyroidism can lead to degenerative athritis. ...Read more

Dr. Tyrone Malloy
261 doctors shared insights

Endocrine System (Definition)

The endocrine system is a group of organs composed of glands that secrete hormones. These hormones have important regulatory functions such as growth, metabolism, ...Read more


Upper Abdomen (Definition)

Draw a transverse line through the umbilicus and the upper abdomen includes every part of the belly above this line and below the ...Read more