Doctor insights on:
Endocrine Bone Diseases In Children
Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more
None: While called an endocrine disorder, to my knowledge, there is no specific organ/gland damage. Any pathologist can to weigh in? ...Read more
There are so many:
Achondroplasia (dwarf), osteogenesis imperfecta (brittle bones, fragilitas ossium)
osteopetrosis (marble bone disease, osteosclerosis) hereditary multiple exotosis (osteochondromatosis) osteochondromatosis of radius and ulna.
Osteochondromatosis of humerus. Cartilage-capped solitary osteochondroma of rib. Enchondromatosis (ollier's disease). ...Read more
No: I do not believe the two are interconnected. ...Read more
No: Paget's disease is a disorder of abnormal bone remodeling. We all lose and build none everyday. In paget's, there's more building than losing, but in an abnormal structure, which makes the bone unstable and prone to breaking. There is often a lot of blood flow to the areas involved and so it can be red and hot. ...Read more
Genetic associations: To name some: there are lysosomal storage disease and hurler's syndrome which can affect both heart and bones. Patients with turner's syndrome are born with bone dysplasia and quite often cardiac defects. Tuberous sclerosis may affect heart and bones also. ...Read more
Yes: Actonel (risedronate) is also commonly used.Get a more detailed answer ›
What types of rare metabolic bone diseases could keep the growth plates from closing? What types of symptoms would help identify if you have them?
Different diseases: This seems like a more complicated question than can be answered on this forum. I would suggest you talk to your Primary Care Physician or an orthopedic doctor if you feel as though there is something going on with you, or at least list some of the symptoms you are having to help get a better answer. ...Read more
No short answer: There are literally hundreds of primary bone or systemic (whole body) disorders that can affect bone formation, metabolism, maintenance. There are just as many benign and malignant tumors that can arise in or affect bone. Expertise in bone diseases crosses many specialties as well quite a few textbooks. ...Read more
No: Paget's is not caused by infectious agents including viruses. ...Read more
Varies: There are multiple disease processes that can involve the bone. Many are metabolic and affect the rate and manner on which bone is formed; osteoporosis and osteomalacia are two examples. Endocrinologists are among the specialists that treat many forms of bone diseases if you need evaluation, as do rheumatologist and some orthopedic surgeons. ...Read more
Rickets: The classic answer is rickets, which is a disease of bone due to severe vitamin d deficiency caused by low dietary consumption and low sunlight exposure. Historically rickets is a disease that affects darkly pigmented individuals. As other, more subtle functions of vitamin d are being described and sunscreen is more widely used, vitamin d levels below recommended levels are becoming more common. ...Read more
Is it true if an adult's growth plates never close post puberty they'll keep growing taller throughout their life? What bone diseases can cause that?
Growth plates: Highly unlikely but if you are concerned see an Endocrinologist and/or a bone specialist ...Read more
No: Not any that I can immediately think of! I'm sure someone else will answer this if they think of one! ...Read more
Heart disease: No direct relationship but one doesn't rule out the other. ...Read more
Pagets disease: Pagets disease of the bone has nothing to do with Paget's disease of the breast. ...Read more
Depends on age: SMalignant bone tumors begin in pre teens as PNET lesions ie Ewings sarcoma. This progress with age to osteogenic Sa. In older teens we see osteogenic sarcoma. Older people get enlarging lesions such as Pagets disease which converts to sarcoma. Cartilagenous tumors can be congenital or isolated as parostoeal chondrosarcomas. With many epithelial malgiancies tumors can spread to bone. ...Read more
Not very much to:
Start. Most people who have paget's disease of bone experience no symptoms. When symptoms do occur, the most common complaint is bone pain.
Pelvis. Paget's disease of bone in the pelvis can cause hip pain.Skull. An overgrowth of bone in the skull can cause hearing loss or headaches.
And others see the link below. ...Read more