Top
30
Doctor insights on: Endocervical Glandular Dysplasia

Share
1

1
I was Diagnosed with Severe Dysplasia (CIN3)involving ectocervical squamous mucosa and fragments of benign endocervical glandular epithelium.?

I was Diagnosed with Severe Dysplasia (CIN3)involving ectocervical squamous mucosa and fragments of benign endocervical glandular epithelium.?

Cervical Cancer: CIN3 is a high risk precursor to cervical cancer and needs to be treated and followed up. Local procedures like LEEP or cone biopsy are important to exclude possible occult invasion. Follow-up following those with visual exam, pap and HPV testing to exclude recurrence or residual are vital. Visual exam to exclude HPV disease of vagina or vulva are also important. ...Read more

Dr. Linda Callaghan
1 Doctor shared a insight

Dysplasia (Definition)

Abnormal cells which may be pre-malignant, but can also result ...Read more


2

2
Epithelial cell abnormality, High-Grade Squamous Intraephithelial lesion, atypical glandular cells and sever dysplasia. What should my concern be?

Epithelial cell abnormality, High-Grade Squamous Intraephithelial lesion, atypical glandular cells and sever dysplasia. What should my concern be?

Pap smear: Is this the result of your pap smear? if yes, then it means moderate or severe cervical intraepithelial neoplasia or carcinoma in situ, which in some cases could lead to cervical cancer. you need Colposcopy and possible biopsy.
Talk to your Gynecologist regarding a treatment plan. ...Read more

3

3
Hi Doctor, what it means small fragment of squamous cells with dysplasia, benign endocervical cells present. Thanks?

Pap: You need to have your pap test repeated in 3 months to see if has reverted to normal, by in itself cells with dysplasia only means that you may have had a past infection or may have HPV ...Read more

5

5
Gastric mucosa showing inflammation, ulceration & high-grade glandular dysplasia?

Gastric mucosa showing inflammation, ulceration & high-grade glandular dysplasia?

Chronic gastritis: The objective findings you describe suggest chronic gastritis. There are many possible causes of this, including hyperacidity, infection with h. Pylori, loss of stomach acid production, or even underlying cancer. It would be a good idea to try to find out what is causing this and doing something to correct it if possible, . ...Read more

6

6
LEEP in Apr. '14, clean margins. Jul. '14 - high grade dysplasia recurs, plus atypical glandular cells. Doc advises hysterectomy. Is this overkill?

LEEP in Apr. '14, clean margins. Jul. '14 - high grade dysplasia recurs, plus atypical glandular cells. Doc advises hysterectomy. Is this overkill?

NO: If truly recurrent dysplasia and no fertility desired, then this is completely a very good option and will give the best result as far as future prognosis. Consider whether removal of the ovaries too may be in your best interest at 46 yo. Discuss with your GYN. Consider a laparoscopic surgery as this allows return to normal faster - but only by really qualified surgeons - not every GYN knows well. ...Read more

7

7
What does it mean when you have benign endocervical glandular ephithelium?

What does it mean when you have benign endocervical glandular ephithelium?

Normal: This means the lining of your endocervical canal in normal. The cervix has an ectocervix which is exposed to the vagina and an endocervix which continues upwards in to the uterus where it is then called the uterine cavity. ...Read more

8

8
What does it mean if you have very rare benign minute fragments of endocervical glandular tissue?

What does it mean if you have very rare benign minute fragments of endocervical glandular tissue?

Endocervical/tissue: A "pap smear" may contain some tissue from the canal leading to the womb (endocervical canal) which grows out over the surface of the cervix and is seen on the pap smear. With a "D&C" some fragments of endocervial glandular tissue will be seen on pathologic diagnostic microscopic exam. This tissue was benign, therefore nothing to worry about. ...Read more

9

9
Atypical endocervical glandular cells favor neoplasty on recent pap. What does this mean?

Atypical endocervical glandular cells favor neoplasty on recent pap. What does this mean?

This is serious: You have cancer until proved otherwise. I hope you do not. If you do, I hope you caught it awhile it is curable. You must follow up ...Read more

10

10
Please explain pap results: "rare hyperchromatic groups of atypical glandular cells, favor endocervical". What could this mean?

Please explain pap results: "rare hyperchromatic groups of atypical glandular cells, favor endocervical". What could this mean?

Colpo: The cells are appearing atypical. So there is suspicion that there could be precancerous or cancerous cells present. Depending on your HPV status your doc most likely will want you to do a colposcopy. ...Read more

11

11
WHAT DOES BENIGN ENDOMETRIUM WITH A PROLIFERATIVE PATTERN, GLANDULAR BREAKDOWN AND DIFFUSE STROMAL BREAKDOWN - SCANT BENIGN ENDOCERVICAL TISSUE MEAN?

WHAT DOES BENIGN ENDOMETRIUM WITH A PROLIFERATIVE PATTERN, GLANDULAR BREAKDOWN AND DIFFUSE STROMAL BREAKDOWN - SCANT BENIGN ENDOCERVICAL TISSUE MEAN?

No worries!: Benign is normal or "non-cancerous". Proliferative just means the cells are in the phase where they are dividing which is normal during the estrogen part of the cycle. Endocervical tissue is just cells that came from inside the cervix - these were also benign! All good news! ...Read more

12

12
Pap results with endocervical glandular cells normal or w/ atypical inflammation. Will treat & retake test. Should I be worried of something serious?

Pap results with endocervical glandular cells normal or w/ atypical inflammation. Will treat & retake test. Should I be worried of something serious?

Normal: It is normal to have endocervical glandular cells on the pap of a woman in your age group. You should also have been tested for high risk HPV and if that test was negative there is extremely little risk of a problem. Inflamation is also frequently found on paps and unless there is other evidence an infection it is not necessary to treat. Hope that helps. ...Read more

15

15
I have just received my results from the leep procedure I had done a week ago, it was CIN iii, endocervical glandular involvement, and clear margins. What are the recurrence rates for my diagnosis?

Need more info: Your recurrence rate is dependent on many personal conditions, including your age. With negative margins your recurrence rate is lower. You need to review this with your physician. ...Read more

16

16
Atypical glandular cells - favor neoplastic was my pap smear test result. Negative colposcopy- & endocervical curretings result. Please explain.

Maybe benign and overcall: It is possible that the cells are reactive and they were over called as worrisome for cancer but in fact are completely normal this would explain the findings. You should have me look at the pap smear I will give you the right answer. ...Read more

17

17
Pap/ HPV reflex to hpv16/18 with ct/cg show endocervical, glandular or metaplastic cells/ or parabasal cells present. Is this simply inflammation?

Pap/ HPV reflex to hpv16/18 with ct/cg show endocervical, glandular or metaplastic cells/ or parabasal cells present. Is this simply inflammation?

In reality, this is: All what you have to do if having history of HPV is doing PAP smear more diligent and vigilant than those without HPV since there is nothing could be done with the past, in attesting: Life is a constant changing and adjusting dynamic process of struggle to cope with reality, certainty, & uncertainty of daily living for survival, growth, & continuation from inception to eternity. ...Read more

18

18
How often should I be tested if I have dysplasia?

Your doctor is your: Your best guide is your doctor who gave you this diagnosis. Most such reports require follow up anywhere between 6 monthly to once yearly. Where is this dysplasia located?
Please check with your doctor about further follow up. ...Read more

19

19
What is the definition or description of: dysplasia?

Abnormal cells: Abnormal cells which may be pre-malignant, but can also result from infections and inflammation. ...Read more

20

20
What is skeletal dysplasia and what are the symptoms?

Dwarfism: Skeletal dysplasia is any of more than 200 conditions that result in the abnormal size and shape of bones and consequent disproportionately short stature, commonly called "dwarfism.". ...Read more

21

21
Skeletal dysplasia? What exactly is this andbwhat are symptoms?

Dwarfism: Disproportionately short stature dwarfism is skeletal dysplasia and it is officially osteochondrodysplasia. There are around 200 different disorders. These people have changes of cartilage and bone growth and can develop changes such as abnormal shape and size of the bones, . ...Read more

22

22
What is cervical dysplasia?

Abnormal cells: This is complicated so stay with me. Hpv is a virus that can infect cells on the cervix. When hpv gets into the cell it can cause the cell to make abnormal proteins. This makes the cell look different under the microscope. If the infection progresses, the cells can become cancerous. This is rare but dysplasia should be addressed. It can go away on its own in some cases. Others need treatment. ...Read more

23

23
Is level 3 dysplasia cancer?

Is level 3 dysplasia cancer?

No but need followup: Type iii dysplasia (pap smear) itself is not cancer means had severe abnormal cells need careful further evaluation, for cancer cells with out invasion (in situ cancer). Must be followed with close observation for any change. ...Read more

24

24
Can dysplasia lead to cancer?

Can dysplasia lead to cancer?

Yes: Progression from normal cell to cancer is like going from white to black over a grey spectrum that keeps getting darker. Normal cell can become dysplastic-- become severe dysplastic -- become low grade cancer-- become high grade. ...Read more

25

25
What's cervical dysplasia mean?

What's cervical dysplasia mean?

Precancerous cells: Dysplasia of the cervix are cells which are showing cellular changes consistent with pre-cancerous lesions. They are graded as low-grade (atypia or cin-1) or high-grade (cin 2, 3, or carcinoma in situ). Low grade cells can be followed while high grade lesions need to be identified (colposcopy) & removed (leep or cone biopsy). ...Read more

26

26
What causes Cervical dysplasia?

What causes Cervical dysplasia?

Usually HPV virus: Dysplasia is one of the early steps in mucosal transformation. The phenotypic structure of the mucosal cells begins to transform toward malignant phenotype and can be picked up on Pap. With newer monoclonals defining the immunogenic protein characterizing cervical Ca changes, normal mucosal cells can be shown to expression tumor protein even though the cells look normal, the ImmunoPap. ...Read more

27

27
What causes dysplasia of cervix?

What causes dysplasia of cervix?

Human Papillomavirus: The most common cause of dysplasia of the uterine cervix is human papillomavirus (hpv). There are several hundred types, but 6, 11, 16, 18, 32, and 33 are the most common. It is a pre-cursor to the development of cancer. However, with cervical cytology (pap smears), people with low grade dysplasia (lgsil) rarely progress, while patients with hgsil will have excision (cone biopsy). ...Read more

28

28
What is this cervical dysplasia?

Precancerous cells: These are abnormal cells in the cervix that have a potential to turn into cancer but are not yet a cancer. ...Read more

29

29
Symptoms of epiphyseal dysplasia?

Mild pain: Multiple epiphyseal dysplasia is an inherited disorder, that affects the joints of the long bones in the arms and legs. There are 2 types based on inheritance (either recessive or dominant)
symptoms are usually mild, and include joint pain, early arthritis, a waddling gait. Some a have other deformities like scoliosis, malformations of the hands and or feet. ...Read more

30

30
What's bronchopulmonary dysplasia?

What's bronchopulmonary dysplasia?

Lung scarring: Bronchopulmonary dysplasia is a condition of airway & lung scarring that occurs in premi's & micro premi's during their prolonged need for ventilation or oxygen in those critical weeks. Xrays are seen to gradually change to show the characteristic patterns that correlate with pathology seen under the microscope when a kid doesn't survive. ...Read more