Doctor insights on:
End Stage Bile Duct Cancer
Yes?: As a rule, stage 4 cancer of the pancreas is incurable. As to being terminal, it depends on the definition. If you mean it will kill the patient at some point, the vast majority of the times the answer is yes. If you mean it will kill the patient right away, it depends on the situation. Never say never, though, some patients have surprised me in the past. Sorry if it is about you or a loved one. ...Read more
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Be strong, KanabarT: Again, please forgive my frankness. You have written perhaps a dozen times describing a variety of events that are typical of the last stages of metastatic colorectal cancer. There is no predicting the time of death, which may be weeks away, but with rising kidney function tests, thrombocytopenia, and dehydration, perhaps it is time to have a frank talk with the physician about comfort measures. ...Read moreSee 2 more doctor answers
No: Primary liver cancer is when the liver cells themselves, the hepatocytes, transform into cancer cells. Bile duct cancer is when the cells lining the bile duct transform into cancer. Primary liver cancer tends to grow large nodules in one place, and doesn't give a lot of symptoms until the tumors are large. Bile duct cancer tends to obstruct the bile ducts and create symptoms, such as jaundice. ...Read moreSee 1 more doctor answer
Not good, but: Each person is unique. Discss this question w/ the doctors involved in treatment. It's not good, but there are certainly cases that will do better than others. All life ends. Stage 4 cancer is quite advanced and life expectancy is shortened significantly. Overall health can matter a lot for how long and how good. ...Read more
It could be commuted: Until recently, colon cancer metastases in the liver were invariably fatal within a few years. However, there are some new biotechnology findings that suggest this may no longer always be the case. Your oncologist would be the person to ask. ...Read moreSee 3 more doctor answers
Possibly: Removal of liver metastases can sometimes be helpful for patients with colon cancer. A remarkable amount of cancer can be removed usually after there has been some response to chemotherapy. If surgery is not recommended alternatives such as radioembolization, chemoembolization, radiosurgery, or rfa or cryoablation may be considered. Get with an experienced team to determine the best course! ...Read moreSee 5 more doctor answers
No: Over a 40 yr. period I have only seen one colon cancer spread to renal parenchyma. Stage 2 kidney cancer is due to a lesion arising in kidney parenchyma and does not represent metastatic tumor to kidney. The lesion that does spread to kidney and eventually spreads though very rare is adenoCa of lung spead to kidney. If no lung lesion we are essentially talking about a primary kidney tumor ...Read moreSee 6 more doctor answers
3 mos mortality risk: Used to prioritize allocation of deceased donor organs for liver transplantation. Meld is a prospectively developed and validated chronic liver disease severity scoring system that uses a patient's laboratory values for serum bilirubin, serum creatinine, and the international normalized ratio for prothrombin time (inr) to predict survival. ...Read moreSee 1 more doctor answer
Not very good: Bile duct cancers are difficult cancers to control unless caught early when they are still localized to one area. Often they are advanced and metastatic at the time of diagnosis, then they are difficult to get rid of. Yet it all depends on the location and the stage of cancer. ...Read more
My dad has stage IV colon cancer with advanced liver mets..inoperable,non curative,on chemo &now coughing a little blood..is the cancer advancing?
Low but not zero: Stage ii colon cancer means no lymph node involvement by definition, but inadequate lymph node sampling (surgical resection) may "understage" the cancer, so make sure enough ln were taken -minimum of 12! even with appropriate surgery, mets may still occur, although very unusual, so discuss with your treating docs. A pet/ct may give some reassurance so ask if this can be done. ...Read moreSee 1 more doctor answer
Not good.: When a liver with cirrhosis is having trouble doing it's job, it's called end-stage liver disease. This means that the liver is beginning to fail. Generally, patient in this setting will die or need transplant within a few years. Having cirrhosis, however, is not the same as end stage liver disease. Only when the liver starts to fail do we call it end stage. ...Read more
Not necessarily: Liver cancer is a pretty bad diagnosis, depends whether it is primary or metastatic. There is treatment though including transplant if you are young and in good shape, and there are many other novel treatments as well. You need close follow up with your doctors at this point and to evaluate all the options. Good luck! ...Read moreSee 3 more doctor answers
Several reasons: Calcium levels in blood are regulated by parathyroid hormone (pth). Some colon cancers make a substance similar to parathyroid hormone, which can increase calcium levels in the blood. Another possibility is that the cancer has spread to the bones, releasing calcium into the blood. ...Read more
Pancreatic cancer, ampullary tumor. Whipple procedure. Spread to liver, not respectable. Chemo for 6 months and continuing. Prognosis?
Poor: While Whipple is the best approach for a primary pancreatic or ampullary lesion, the recurrence rate at 1-2 yrs is 90%. Chemo either of the FOLFIERI or Genciabine /Abraxane combo have limited effects on liver mets which in pancreas are not considered amenable to resection. There is an FDA protocol using specific monoclonals targeting pancreas that might be available but only after chemo failure ...Read more
Terminal pan can. No more treatments/ chemo. Sent home with a home care nurse. Biliary drainage tube from tumor blocking bile duct. Life expectancy?
Limited: Make sure that your oncology team has lots of experience with treating pancreatic adenocarcinoma, and that they have access to clinical trials. Across the board, the life expectancy for terminal pancreatic cancer is limited, in the months range. But for appropriate candidates, there are clinical trials that might be worth considering. Best wishes, and try to keep your chin up! ...Read more
It is widespread.: Staging across cancers can be complex, but stage IV usually means it has spread. This website is a nice place to learn about cholangiocarcinoma (another term for biliary tree cancer): http://www.Macmillan.Org.Uk/cancerinformation/cancertypes/bileduct/bileductcancer.Aspx. ...Read more
10-15% 5 years: Herman cain is a survivor.Get a more detailed answer ›
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