Doctor insights on:
End Stage Bile Duct Cancer
Bile ducts: Are buried in the liver, and also are outside, picking up gall bladder secretions before joining the pancreatic ducts. Biliary cancers are divided by their location, and that indicates means of treatment. They are not common, called klatskin tumors, few are resectable; most are not. Ca-19-9 may be quite hi. ...Read more
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Aggressive tumor: Tumor can arise intrahepatically requiring partial hepatectomy id possible. It is also found in the common duct outside the liver. The jaundice present can be relieved by a stent from ERCP. Chemo and radiation frequently employed. Within the liver distant metastasis frequently develops. Pancreatic drugs like Gemcitabine may help. ...Read more
Not very good: Bile duct cancers are difficult cancers to control unless caught early when they are still localized to one area. Often they are advanced and metastatic at the time of diagnosis, then they are difficult to get rid of. Yet it all depends on the location and the stage of cancer. ...Read more
Jaundice: Bile duct cancer is uncommon but carries a poor prognosis. It will typically impede the flow of bile from the liver to the small intestine thus causing obstructive jaundice (yellowish discoloration of eyes and skin). Pain in the upper abdomen, weight loss and nausea may be noted. ...Read more
Very difficult: Bile duct cancers behave in a similar fashion to pancreatic cancer. When localized to the common duct and resected, the patient has a chance, especially post RT with gemcitabine. When the tumor spreads to bone I'm not sure that combo chemo with any of the available monoclonal can demonstrate any effect on survival. ...Read more
Yes: It will not be curable but palliation may be obtained, sometimes as simply as by radiating the bone metastases. ...Read more
Dad's dying from bile duct cancer&has reached stage where he's bed bound, not eating&has become confused. Worried he's suffering. How long can this last?
Palliative care: I would recommend you to talk to his oncologist and ask for palliative care team/hospice care- to help him. Unfortunately, from your limited information, I do not expect this will last long. To make sure that he is not suffering etc- strongly consider hospice care. ...Read more
Mother died from bile duct cancer. She was so healthy her whole life, never had any problems. This Cancer came out of nowhere. Causes?
Is bile duct cancer hereditary? My mother died from it at age 65 in 2001.Do I need any special tests? What is the cause? Any new treatments?
No screening: Bile duct cancer very rare. Appears with jaundice and with work up is either intrahepatic Klatskin tumor which can be resected or in Porta, a common duct lesion. Most cholangiolar Ca are virulent and metastasize to all sites in body. Chemo similar to that of pancreatic Ca but overall response poor. No preventative work up of value. ...Read more
My dad has been diagnosed with bile duct cancer. He has severe swelling of legs. He has been put on diuretics. How long for this fluid to go?
I have urq pain, now bone pain on the right side and get night sweats. Can a CT scan always pick up pancreatic or bile duct cancer?
No test is perfect!: No test is 100 percent accurate. Although a multiphase ct with contrast is a very good test for pancreatic or bile duct cancer, it is not a perfect test. Mri, mrcp and ERCP are all tests that may be useful. Generally, imaging for this problem begins with a ct, with the additional tests based on the ct results, as well as lab tests and other examinations. ...Read more
Nothing good yet: There is as of yet, no proven monoclonal antibody (moab) for this type of cancer. For some of the GI cancers, anti-egfr antibody like cetuximab (erbitux) has been modestly useful. You can ask your oncologist whether he/she will consider adding this moab to your chemotherapy regimen in case you are still on chemo or being offered chemotherapy with Cisplatin and gemcitabine. ...Read more
Bile duct cancer:
1. You can play.
2. You can put a stent in to keep it open or
3. You can put a drain in so bile comes out in a bag.
But discuss with your Dr who knows you best. Good luck. If it is you you are talking about I would take care of everything you need to take care of soon. But as Yogi said its hard to make predictions. Especially about the future. ...Read more
My sister was told her extra hypetic biliary duct was enlarged is that bile duct cancer? She has lost about 30 lbs in less than 2 mo's, has really sharp stomach pains, diarriha, no appetite, & nausea. Was admitted to the hosp & was told what test revealed
The liver makes bile, the substance that makes the stool brown. The bile comes out from the liver through bile ducts. Normally the bile goes into the gallbladder, where the bile is concentrated and stored for excretion into the intestine after eating, to assist in digestion. The bile ducts are classified as: intrahepatic (within the liver) and extrahepatic (outside the liver, i.e. From the liver to the duodenum thru the common bile duct). The common bile duct tranverses the pancreas where the pancreatic duct joins and then exits through the ampulla of vater. Therefore blockage at the ampulla, in the pancreas and in the common bile duct itself can lead to extrahepatic dilitation. The most common reason for a slightly enlarged bile duct is after the gallbladder is removed and the bile duct enlarges to accommodate the increased flow of bile. This is usually not associated with any abnormalities in the liver function tests. If there is a blockage due to a stone in the bile duct, or from a mass, such as a cancer or from scarring such as from pancreatitis, the liver function tests will be abnormal and the patient may become jaundiced, or yellow. The second most common reason for bile duct dilation is a common bile duct stone, usually associated with gallstones.
The weight loss, loss of appetite is concerning and she should have additional testing, including an ultrasound or ct scan as well as bloodwork. She should see a gastroenterologist or general surgeon. ...Read more
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