Doctor insights on:
End Of Life Symptoms Of Stage Iv Melanoma
A condition in which some element of your skin--which is one of the most complex organs in the body--degenerates into cancer. The three most common types of skin cancer are: basal cell, squamous cell, and melanoma which occur in that order and degree of aggressiveness. Although heredity plays a major role, sun exposure and tobacco use and ...Read more
Metastasis: Stage IV (4) melanoma is the highest stage that a melanoma can reach. It is diagnosed by finding distant spread or metastasis to other parts of the body. Stage is different from clark's levels and breslow levels, although these can impact lower stages. (ajcc cancer staging manual, 7th ed., 2010). ...Read more
Studies are underway: There are studies currently underway of this drug in certain cases of stage IV melanoma. It is only available in a research studies, in certain locations, and only patients who meet strict entry criteria are eligible. Patients and families can find these studies listed at www. Clinicaltrials. Gov ...Read more
Approx 15% live 5 yr:
Stage iv: the 5-year survival rate is about 15% to 20%. The 10-year survival is about 10% to 15%, according to cancer.Org.
So about 1 out of 5 or 6 chance of living five years.
Some new drugs are coming out for melanoma, and there can be spontaneous remissions. But distant spread of melanoma is a tough one.
Good luck. ...Read more
Hospice care: It can be overwhelming for the family. Get hospice involved immediately. They have resources to help the whole family through this tough time. ...Read more
Several weeks: At times melanoma has been known to go into spontaneous remission. However the chemotherapeutic agents attempted to be used for control have not been too effective. Recently drugs like the antiCTLA's (anti cytotoxic lymphocyte antigen) and the PD-1's have produced a rapid regression in metastasis that have lasted long periods of time. Newer tyrosine kinase inhibitors are adding to the results ...Read more
I'm 41 y/o F, stage 4 met Melanoma. On Zelboraf & Mekinist. ESR of 85 & C-Reactive Protein 10. Can meds cause this??
Unrelated: ESR and C-reactive protein are laboratory values that are usually not very helpful in following patients with metastatic melanoma. Generally, scans such as CT or MRI are more helpful. Some patients do have an elevation in a laboratory value called LDH which can be helpful to follow. ...Read more
New mole show up one year ago, doesn't fit ABCDE and derm said it is fine. Cant shake the thought that it may not be. Scared stage 4 melanoma, crazy?
Probably OK: You have done the right thing by having a dermatologist check out your mole. Fortunately he/she thinks it is normal. Melanoma is uncommon at any age but especially so at your age. If you cannot shake this feeling, then a second opinion with another dermatologist would be in order. ...Read more
How long can you live with stage 4 metastatic melanoma with mets spread into the brain. What kind of treatment is best?
Radiation +/- surg: If there is only one or two brain metastasis it may be treated with surgery + radiation therapy. More than that number of brain mets usually treated with radiation alone. Disease in body may respond to targeted therapy (e.g. Zelboraf + Mekinist). Yervoy has also helped many. Prognosis depends on a large number of factors which I cannot assess. ...Read more
Are the survival rates with stage 4 metastatic melanoma with mets to the brain, liver and skin really poor?
If I have stage 4 melanoma, does that increase my chances of getting breast cancer or another form of cancer?
Not all that signifi: It does not increase the risk. So I would ask you not to worry any more than you already are if you have stage 4 melanoma. I hope you are not confusing it with level-4 melanoma which means non- metastatic melanoma (curable) as opposed to metastatic melanoma (stage-4) which is less commonly curable. ...Read more
How long does this person have with stage 4 metastatic melanoma w/ several mets in small bowel and brain? Treatments?
Depends: Traditionally, this would be associated with a short survival. But over the last 3 years, a number of new chemotherapy drugs are available which may significantly extend the quality and duration of patients with metastatic melanoma. Ask your doctor if your melanoma is "BRAF mutant". If so, you are a candidate for a class of drugs. But don't delay, brain mets can be dangerous if not treated. ...Read more
My dad, stage 4 small cell lung cancer. Gets out of breath, takes naps, losing weight, and today, coughed up blood 2 times. Is this end of life signs?
Lung Cancer: It sounds like he is not doing well. However, regarding when he will die - his physician or his medical team would be best to determine if he is close to death. Take care. ...Read more
Could a teenage resist treatment for stage 4 metastatic melenoma with mets to brain, liver and skin?
Unsure of question: I'm not sure I'm reading your question correctly. Are you asking if a teenager can REFUSE treatment? It depends upon age of the teenager and the state they live in. If your question is can a teenager be "resistant" to treatment, meaning the treatment won't have much likelihood of working, the answer is yes. How sad- stage 4 melanoma is very rare in teens - I don't think I've ever heard of a case. ...Read more
What is the prognosis with stage 4 scc skin cancer with mets to lung bone brain and the cancer originated in the leg?
For dementia pt especially what are end of life symptoms? Pt suddenly to be bed bound, robust appetite poor almost overnight, back on o2, hiccups.
Weight loss, day-nig: Generally, dementia is considered advanced when the pt experiences severe memory loss (can't recognize own family) & forgets how/when 2 eat, toileting, chew, & use basic body functions. This results in weight loss, incontinence, choking/gagging, not able to clear secretions, & loss of 24-hr cycle (days & nights get mixed). Read "The 36-hour day" by Nancy Mace & Peter Rabins- a gr8 descriptive book ...Read more
What are the end of life symptoms for advanced adendouscarcina nsclc w/ mets to brain, bones and now liver. 14 months dx?
Most melanomas are brought to a doctor’s attention because of signs or symptoms a person is having. What are they?
Remember your abcd's when thinking of melanoma. Look for moles with
boarders that are irregular
color differences within the same mole
diameter greater than 6mm
also any new mole or old that starts to itch, bleed or ulcerate should be of concern. Another rule is the ugly duckling rule. Which refers to a mole that looks distantly different from the others on your body. ...Read more
Malignant Melanoma: Aad malignant melanoma screening: asymmetry: 1 half is unlike the other. Border: irregular, scalloped or poorly defined. Color: varied with shades of tan, brown or black; or white, red or blue. Diameter: > 6 mm. Evolving: mole /skin lesion looks different from the rest or is changing in size, shape or color. An irregular mole that itches, bleeds or is painful is worrisome for possible cancer. ...Read more
Lymph nodes.: The main thing in stage iii melanoma in anyone is that there are palpable lymph nodes in the vicinity of the tumor/melanoma. It has a 50% 5 year survival if only one node is involved and a 15-20% 5 year survival if 4 or more nodes are involved. Survival is improved with interferon-alpha treatment. Chemotherapy and immunotherapy may alsso help. Please see your doctor for the best treatment plan. ...Read more
I did a search for diagnosis of some of my symptoms and came up with melanoma. What do doctors look for to diagnose it?
Skin mole: Melanoma doesn't usually hurt or cause symptoms. Sometimes it itches or bleeds easily. If it is very large it can cause pain. If it has spread to other organs it can also cause symptoms. But if it is small and just on the back, it doesn't cause much in the line of symptoms. Visit your doctor to talk about your options to determine if it really is melanoma (punch biopsy or shave biopsy). ...Read more
Malignant Melanoma.: AAD Malignant Melanoma screening: ASYMMETRY: 1 half is unlike the other. BORDER: irregular, scalloped or poorly defined. COLOR: varied with shades of tan, brown or black; or white, red or blue. DIAMETER: > 6 mm. EVOLVING: mole /skin lesion looks different from the rest or is changing in size, shape or color. An irregular mole that itches, bleeds or is painful is worrisome for possible cancer. ...Read more
Use ABCDE RULE:
It's best to see a dermatologist but a good rule of thumb is the abcd guidelines
a=asymmetry of lesion
b=border is irregular
c=colors are multiple and not consistent
d=diameter is greater than 6mm
e=evolution of lesion with changes and enlargement. ...Read more
Many disguises: I have seen melanoma spread nearly everywhere you can imagine, and the site of metastasis dictates the symptoms that may occur. Common sites include lymph nodes, lung, liver, bone, and small intestine. Lymph nodes: a lump in the underarm, neck, or groin. Lung: cough, shortness of breath or bloody sputum. Liver: jaundice or pain. Bone: pain or fracture. Small intestine: bloody bm, blockage. ...Read more
How do I know I've got a melanoma? Which are the symptoms? Does it have to look all black? Or how?
There is considerable variation in color size and shape of melanomas. It does not have to be all black. It would be useful to see your doctor for an evaluation. You may consult this site for the various images of melanomas.
https://images. Search. Yahoo. Com/yhs/search;_ylt=A0LEVjzd8bJU_5AAdBQPxQt.;_ylu=X3oDMTBsa3ZzMnBvBHNlYwNzYwRjb2xvA2JmMQR2dGlkAw--? _adv_prop=image&fr=yhs-mozilla-001&sz=all&va=melanoma+skin+cancer&hspart=mozilla&hsimp=yhs-001 ...Read more
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