Doctor insights on:
Rheumatoid arthritis for 7 yrs. On methotrexate & prednisone. Tried so many drugs (orencia, enbrel, humira...). Feeling defeated. What else can I try?
Other choices: Some older drugs such as Plaquenil may help, especially with fatigue. There are also newer drugs that act via different mechanisms such as actemra. I assume the diagnosis of RA is definite. If not, retest other possibilities. An exercise program may be very beneficial, especially if you start slowly and build up with hurting yourself. Don't give up hope. You can get better. ...Read moreSee 1 more doctor answer
Enbrel: There are many potential dangers to taking enbrel, which should be discussed with your physician. Enbrel suppresses your immune system, which can increase the risk of many forms of infections, including upper respiratory infections, tb, hepatitis b reactivation, and opportunistic fungal infections. Immune suppression can also increase the risk of developing cancer such as lymphoma and leukemia. ...Read moreSee 1 more doctor answer
Is it possible to build a tolerance to enbrel and how til it could happen. I'm haven't been on it a year and the effects are decreasing ?
Well tolerated excep: Despite the fda requiring the package insert to warn one of the development of cancer with the drug, there has been many studies refuting the increased propensity to develop cancer; either lymph, skin or other "solid tumors." the one big risk is infectious complications. The drug does not cause infections; but, it makes it difficult to fight off tuberculosis, fungal infections and viruses. ...Read moreSee 1 more doctor answer
Few days to 3-4 week: Some people have a dramatic response, while others may take up to 3 months or more. Depending on how your joints are doing will aid your physician in telling about your response. It also depends on your diagnosis of the reason you are taking it: ra, psoriasis or psoriatic arthritis, ankylosing spondylitis or jia. ...Read moreSee 1 more doctor answer
I am going to start enbrel and i keep reading how sick people become. Is it more in the 1st few months?
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