Doctor insights on:
My RA doc wants me to take Enbrel/ Humira (adalimumab). Very afraid of the side effects & I'm already blind in 1 eye. What else can I take instead?
Talk to RA doctor: These are issues which need be discussed with your RA doctor. In medicine, most decisions made are based on risk/benefit ratio and without knowing that, it is impossible to provide you with an answer in this type of interaction. ...Read more
Rheumatoid arthritis for 7 yrs. On methotrexate & prednisone. Tried so many drugs (orencia, enbrel, (etanercept) humira...). Feeling defeated. What else can I try?
Other choices: Some older drugs such as Plaquenil may help, especially with fatigue. There are also newer drugs that act via different mechanisms such as actemra (tocilizumab). I assume the diagnosis of RA is definite. If not, retest other possibilities. An exercise program may be very beneficial, especially if you start slowly and build up with hurting yourself. Don't give up hope. You can get better. ...Read more
Is there a waiting period between changing from enbrel (etanercept) to humira? If so, how long? Then how long before humira begins to work?
One week: I would start Humira one week after your last Enbrel (etanercept) injection. There is no hard and fast rule. I have seen Humira work as quickly as within two weeks and as long as three months. These medications should be given for at least three months before switching. Good luck. ...Read more
On actemra (tocilizumab) IV (dose increase in dec)and methotrexate for 5 mon now but still having bad flare ups. Tried humira, enbrel, etc. Since diagnosis in Dec 2013?
Your question is?: Your have not asked a question. This issue needs to be discussed with your rheumatologist. No one can give you specific advice over the internet without a complete history and exam. ...Read more
What is it like to have any experience with blood monitoring for anti tnf therapy (humira/enbrel) whilst traveling for multi stop flights abroad?
See details: People who are stable on TNF biologics do not require blood test monitoring more than once every 3 months. Those in my practice who have been stable for years only have monitoring every 6 months. ...Read more
Would a doctor ever prescribe an anti-TNF such as Enbrel (etanercept) or Humira for mechanical non malignant back pain or a lumbar strain?
Although: Evidence may show some benefit, cost make it impractical. ...Read more
Is there another way to treat my psoriasis from psoriatic arthritis? So far have tried uv therapy, low dose radiation treatment, methotrexate, humira, enbrel, halabetasol ointment, coal tar, hylatopic, and any other cream my dermatologist could think of.
Wow: You have been through a lot. I would try the mayo clinic in mn. ...Read more
Same!: They work similarly!Get a more detailed answer ›
See list: In the usa, the available tnf inhibitors are Adalimumab (humira), Etanercept (enbrel), certolizumab pegol (cimzia), golimumab (simponi), and Infliximab (remicade). ...Read more
See below: The important side effects that have been most extensively related to tnf blockers include: lymphoma, infections including tuberculosis, congestive heart failure, demyelinating disease, a lupus-like syndrome, induction of auto-antibodies, injection site reactions, and systemic side effects. ...Read more
RA + psoriasis. MTX allergy. Enbrel (etanercept) non effective. Humira semi-effective but Vectra score 30 with extreme fatigue. MD wants to try Xeljanz?
RA + psoriasis: There are a number of newer medications that could help you. Xeljanz works by disrupting cytokine and growth factor signaling pathways. A trial of the medication is useful to see whether it helps you. Other medications that might help include Remicade (infliximab) and Apremilast ...Read more
Switching meds: The current recommendation is to try a medication with a different mechanism of action. That being said, before there were so many options, switching between Enbrel and Humira was quite common. Sometimes it helps, just as sometimes one pill in a class of drugs works better than another. ...Read more
What's average amount of time people can take biologics (ex: humira (adalimumab) or enbrel) before developing an immunity to it? Do all patients develop immunity?
See below: Patients are more apt to develop resistance to biologic if they are not on methotrexate. However; not all patients are candidate to be on methotrexate. Some patients never have a problem and some do. It is hard to comment on the average amount of time because it is an individual phenomena. ...Read more
Was on humira (adalimumab) weekly&psoriasis came back. Now on enbrel&25mg methotraxte. Do u think psorias will clear? Y did humira (adalimumab) stop working? Stress overpower it?
Both work: It's your these medicines are effective. The reason medication stop working may depend on many factors. Sometimes the body develops resistance to a medication that is working fine. The resistance can occur because of antibodies against the drug. It can also occur because the mechanism of the disease of the illness can change differently at the molecular level. You doctor can better answer this. ...Read more
Child has JRA failed enbrel and had side effects from it so dr gave choice humira or remicade (infliximab) Which is better? I'm confused snd do know what to do!
TNF Inhibitors: All of the medications offered to your child work in similar ways the difference is how the meds are given. Humira (adalimumab) is an injection that can be done at home every two weeks, while remicaide is an IV medication that must be done in an infusion unit or hospital. These medication have similar side effects and benefits. My advice is try the medication that is least disruptive to your lifestyle. ...Read more
Dx:ra. Enbrel (etanercept) not effective after 6 mo. Humira 2x mo prescribed. Liver can not tolerate mtx. What medication can replace mtx to make humira work best?
Psoriasis+psor. Arthritis. Methotrexate 15mg for 2 mos. Already+humira weekly. Dr say stelera no good for arthr...Says remicade (infliximab) or enbrel maybe. Ok?
Besides enbrel (etanercept) and humeria what are other biolgics or infusions can a. 7 year old take for juvenile idiopathic arthrits?
See list: Remicade, Rituxan, Actemra, Simponi (golimumab), (golimumab) Cimzia, Orencia. Remicade, Simponi (golimumab) and Cimzia are TNF agents. ...Read more
Dear doctors, as a person with ankylosing spondylitis, could you tell about the price of tnf-inhibitors, such as etanercept, infliximab, adalimumab?
Well tolerated excep: Despite the fda requiring the package insert to warn one of the development of cancer with the drug, there has been many studies refuting the increased propensity to develop cancer; either lymph, skin or other "solid tumors." the one big risk is infectious complications. The drug does not cause infections; but, it makes it difficult to fight off tuberculosis, fungal infections and viruses. ...Read more
See below: Once you have stopped taking enbrel, (etanercept) the immune system should become more responsive on its own. There is no way to "boost" the immune system that is of any scientific merit. ...Read more
No.: Not as of this time.Get a more detailed answer ›
Very effective!: CAN BE TAKEN WITH OTHER DRUGS IN USE FOR AS! ...Read more
Bad: You will be disoriented, dyscombobulated high and weak, dizzy, nauseated. ...Read more
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