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Doctor insights on: Enbrel Etanercept Precautions

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Anyone taking humira (adalimumab) for rheumatoid arthritis?

Anyone taking humira (adalimumab) for rheumatoid arthritis?

Many patients!: Results are very good, particulary when used alone and better with methotrexate. The dirrence with Remicade (infliximab) is that it binds to tnf-a rendering ineffecftive. It is completely human in origin. A good choice for those who do prefer home sc injection, every two weeks. It is my favorite tnf-a class drug. ...Read more

Dr. Robert Lowe
125 doctors shared insights

Etanercept (Definition)

Etanercept is an immune system suppressor which is a kind of ...Read more


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Methotrexate vs humira (adalimumab), rheumatoid arthritis question?

Methotrexate vs humira (adalimumab), rheumatoid arthritis question?

MTX vs Humira (adalimumab): These drugs fight RA in completely different fashions. Mtx is the consensus first round choice of drugs to treat ra, both by the acr and eular (european version). Most, if not all, insurances require treatment failure with mtx before you start humira, (adalimumab) a much more expensive drug. In most cases, even if Humira (adalimumab) is started, patients will remain on mtx. ...Read more

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Anyone tried enbrel (etanercept) for treating rheumatoid arthritis?

Anyone tried enbrel (etanercept) for treating rheumatoid arthritis?

Many patients: Rheumatoid arthritis can often be controlled with some of the newer medications including enbrel (etanercept). Many patients are saved from irreversible crippling of the joints. The key is to get early diagnosis and effective treatment to prevent worsening. Enbrel (etanercept) is a biologic response modifier meaning that the drug is made by a biological system. The drug can be very effective. Untreated RA has huge risks. ...Read more

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Methotrexate vs humira (adalimumab), rheumatoid arthritis?

Methotrexate vs humira (adalimumab), rheumatoid arthritis?

Methotrexate: is a first line drug for rheumatoid arthritis, used frequently with hydroxchoroquine and sulfasalazine. Humira is an expensive biologic for those who have failed traditional first line regimens!

Humira works well for RA, but it is second line! ...Read more

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Is enbrel (etanercept) safe when breastfeeding?

Is enbrel (etanercept) safe when breastfeeding?

Maybe okay: Sorry for saying maybe, but there are no studies about using Enbrel (etanercept) while breast feeding. That said, it is unlikely that Enbrel (etanercept) passes into breast milk in large amounts. Also, Enbrel (etanercept) is not well absorbed orally, so a baby would not likely absorb a large amount of medication through breast feeding, either. If you need to use enbrel, (etanercept) it should be okay. Speak with your pediatrician. ...Read more

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How is enbrel (etanercept) used for treating rheumatoid arthritis?

How is enbrel (etanercept) used for treating rheumatoid arthritis?

Second line.: While Enbrel (etanercept) can be used alone, it works better in tandem with methotrexate. It is given by subcutaneous injection once per week, the dose being dependent on body size. It is also indicated for psoriatic arthritis and spondylitis. Most insurers want the patient to have been on lesser drugs. These would include incomplete response to mtx, sfz, and ho-q. It binds to tnf-alpha, which caues inflamm. ...Read more

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Is methotrexate or humira (adalimumab) better for rheumatoid arthritis?

Is methotrexate or  humira (adalimumab) better for rheumatoid arthritis?

It's u as much as Rx: Again, this is a question for the treating specialist, most likely a rheumatologist. When treating a disorder like ra, there are a variety of medications that have been effective; as with everything else in medicine, no one size fits all, and the right drug or combo for each must be assessed over time by a specialist. ...Read more

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What's more effective for pustular psoriasis, methotrexate or enbrel (etanercept)?

What's more effective for pustular psoriasis, methotrexate or enbrel (etanercept)?

Both: Both can be effective, personally i feel Enbrel (etanercept) is safer. There are other options. Talk it over with your dermatologist. ...Read more

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Psoriasis+psor. Arthritis..Methotrexate 15mg for 2 mos. Already+humira weekly..Dr say stelera no good for arthr...Says remicade (infliximab) or enbrel maybe..Ok?

Nod to others:: Humira is a tnfa antibody, and is similar to envbrel. Remicade (infliximab) is an antibody to the tnfa receptor, so it works differently. But i would have tried you on leflunomide, and oral drug, before starting biologics. ...Read more

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What are Enbrel (etanercept) side effects?

What are Enbrel (etanercept) side effects?

See details: Infection is the greatest risk. Other side effects include reduction in blood counts, liver disease, neurologic disorders and a possible increased risk of lymphoma. ...Read more

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Enbrel (etanercept) 50 mg sq x 3 months for RA + psoriasis. Very little improvement. Any downside to increasing to enbrel (etanercept) 50 mg sq twice weekly? Mtx not tolerated.

Enbrel (etanercept) 50 mg sq x 3 months for RA + psoriasis. Very little improvement. Any downside to increasing to enbrel (etanercept) 50 mg sq twice weekly? Mtx not tolerated.

No real downside: Tnf inhibitors like Enbrel don't increase in toxicity like other meds do. Increasing the dose to 50mg twice weekly is a good idea.But, if you don't also take methotrexate, for any reason, you will be more likely to develop antibodies against the Enbrel and neutralize it--causing it to lose most or all effectiveness.If increasing Enbrel does not work, consider another med like Humira or remicade (infliximab). ...Read more

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Can takeing enbrel (etanercept) while pregnet for psoriatic artharits harm a growin fetus?

Can takeing enbrel (etanercept) while pregnet for psoriatic artharits harm a growin fetus?

No: My drug database shows that this is pregnancy class b, the safest class of medication. Studies show no risk of adverse fetal effects. ...Read more

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Is arava (leflunomide) effective for rheumatoid arthritis?

Is arava (leflunomide) effective for rheumatoid arthritis?

It may be...: Again, this is a question for the treating specialist, most likely a rheumatologist. When treating a disorder like ra, there are a variety of medications that have been effective; as with everything else in medicine, no one size fits all, and the right drug or combo for each must be assessed over time by a specialist. ...Read more

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Is there anybody taking anti-tfn infliximab for rheumatoid arthritis?

Many patients!: Results are very good, particulary when used alone and better with methotrexate. The dirrence with Remicade (infliximab) is that it blocks the tnf-a receptor, rather than binding tnf-a itself, but it accomplishes the same thing. It's infusion intervals are longer, because the turnover of recptors is slower than the production of tnf-a itself. A good choice for those who do not want to inject themselves sc. ...Read more

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How good is enbrel (etanercept) for treating rheumatoid arthritis?

How good is enbrel (etanercept) for treating rheumatoid arthritis?

Very effective.: But frequently unecessary in most of my RA patients. Combinations inclduing mtx with sulfasalazine, hydroxychlorquine, perhaps doxycycline, or Leflunomide should be tried before starting enbrel, (etanercept) unless you have overwhelming inflammatory disease. Noenthless, Enbrel (etanercept) with mtx is better than either alone! ...Read more

Dr. Robert Lowe
143 doctors shared insights

Enbrel (Definition)

Enbrel is an immune system suppressor which is a kind of ...Read more