Doctor insights on:
Enbrel Etanercept Precautions
Many patients!: Results are very good, particulary when used alone and better with methotrexate. The dirrence with Remicade (infliximab) is that it binds to tnf-a rendering ineffecftive. It is completely human in origin. A good choice for those who do prefer home sc injection, every two weeks. It is my favorite tnf-a class drug. ...Read more
MTX vs Humira (adalimumab): These drugs fight RA in completely different fashions. Mtx is the consensus first round choice of drugs to treat ra, both by the acr and eular (european version). Most, if not all, insurances require treatment failure with mtx before you start humira, (adalimumab) a much more expensive drug. In most cases, even if Humira (adalimumab) is started, patients will remain on mtx. ...Read more
Many patients: Rheumatoid arthritis can often be controlled with some of the newer medications including enbrel (etanercept). Many patients are saved from irreversible crippling of the joints. The key is to get early diagnosis and effective treatment to prevent worsening. Enbrel (etanercept) is a biologic response modifier meaning that the drug is made by a biological system. The drug can be very effective. Untreated RA has huge risks. ...Read moreSee 2 more doctor answers
Maybe okay: Sorry for saying maybe, but there are no studies about using Enbrel (etanercept) while breast feeding. That said, it is unlikely that Enbrel (etanercept) passes into breast milk in large amounts. Also, Enbrel (etanercept) is not well absorbed orally, so a baby would not likely absorb a large amount of medication through breast feeding, either. If you need to use enbrel, (etanercept) it should be okay. Speak with your pediatrician. ...Read more
Second line.: While Enbrel (etanercept) can be used alone, it works better in tandem with methotrexate. It is given by subcutaneous injection once per week, the dose being dependent on body size. It is also indicated for psoriatic arthritis and spondylitis. Most insurers want the patient to have been on lesser drugs. These would include incomplete response to mtx, sfz, and ho-q. It binds to tnf-alpha, which caues inflamm. ...Read moreSee 1 more doctor answer
It's u as much as Rx: Again, this is a question for the treating specialist, most likely a rheumatologist. When treating a disorder like ra, there are a variety of medications that have been effective; as with everything else in medicine, no one size fits all, and the right drug or combo for each must be assessed over time by a specialist. ...Read moreSee 1 more doctor answer
Very effective!: Good drug for severe RA!Get a more detailed answer ›
Can i take enbrel (etanercept) and methrotrexate same day as antibiotic sulfamethoxale - trimethoprim. 50 mg enbrel (etanercept) 2.5mg x5.
Dx:ra. Enbrel (etanercept) not effective after 6 mo. Humira 2x mo prescribed. Liver can not tolerate mtx. What medication can replace mtx to make humira work best?
Enbrel (etanercept) 50 mg sq x 3 months for RA + psoriasis. Very little improvement. Any downside to increasing to enbrel (etanercept) 50 mg sq twice weekly? Mtx not tolerated.
No real downside: Tnf inhibitors like Enbrel don't increase in toxicity like other meds do. Increasing the dose to 50mg twice weekly is a good idea.But, if you don't also take methotrexate, for any reason, you will be more likely to develop antibodies against the Enbrel and neutralize it--causing it to lose most or all effectiveness.If increasing Enbrel does not work, consider another med like Humira or remicade (infliximab). ...Read moreSee 1 more doctor answer
It may be...: Again, this is a question for the treating specialist, most likely a rheumatologist. When treating a disorder like ra, there are a variety of medications that have been effective; as with everything else in medicine, no one size fits all, and the right drug or combo for each must be assessed over time by a specialist. ...Read moreSee 1 more doctor answer
Many patients!: Results are very good, particulary when used alone and better with methotrexate. The dirrence with Remicade (infliximab) is that it blocks the tnf-a receptor, rather than binding tnf-a itself, but it accomplishes the same thing. It's infusion intervals are longer, because the turnover of recptors is slower than the production of tnf-a itself. A good choice for those who do not want to inject themselves sc. ...Read more
Very effective.: But frequently unecessary in most of my RA patients. Combinations inclduing mtx with sulfasalazine, hydroxychlorquine, perhaps doxycycline, or Leflunomide should be tried before starting enbrel, (etanercept) unless you have overwhelming inflammatory disease. Noenthless, Enbrel (etanercept) with mtx is better than either alone! ...Read more
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