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Doctor insights on: Eliminate Biliary Cirrhosis

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Dr. Bernard Seif
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Biliary (Definition)

Biliary means anything related to the production, storage, secretion, or flow of bile, whether in the liver, bile ducts, gallbladder, ...Read more


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Is primary biliary cirrhosis hereditary?

Is primary biliary cirrhosis hereditary?

Basically no: There's a pair of genes that carry the ability to develop the disease and these run in families, but it's not inherited like sickle cell, huntington's or some of the other familiar entities. http://www.medicalnewstoday.com/releases/151640.php. ...Read more

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Pathophysiology of liver cirrhosis?

Pathophysiology of liver cirrhosis?

See below: Scar tissue in the liver as a result of different kinds of injuries. The significance is related to the chronicity for the injury and especially whether the injury is ongoing. ...Read more

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What differentiates primary biliary cirrhosis from other types of cirrhosis?

Location of inflam: Agree with dr. Edmisson. Pbc is autoimmune disease affecting bile ducts; can eventually lead to progressive liver disease and cirrhosis (scarring). Othe types of cirrhosis usually involve inflammation of the liver cells, due to infection (like hep b, c), toxic chemicals, metabolic disease e.g.Nonalcoholic fatty liver (seen in obesity, diabetes) iron overload, damage from alcohol, autoimmune. ...Read more

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What is chronic liver parenchymal disease with cirrhosis; varices and ascites?

What is chronic liver parenchymal disease with cirrhosis; varices and ascites?

This sounds serious: To translate, you have liver cell damage and scarring (cirrhosis), which caused abnormally elevated portal vein pressures which caused venous distention in esophagus (varices). You also developed fluid in abdominal cavity, because of the high portal vein pressure. This imaging study is showing advanced stage of liver disease. You must get a specialist to treat you. ...Read more

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Can mild diffuse fatty liver infiltration cause elevated bilirubin? Gallbladder was removed with no stones.

Can mild diffuse fatty liver infiltration cause elevated bilirubin? Gallbladder was removed with no stones.

Maybe: Multiple causes of elevated bilirubin. Liver inflammation, hepatitis, acquired gilbert's syndrome, postoperative status, etc. Should not remove a gallbladder without stones only for a blood test finding, which hopefully was not your situation. ...Read more

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Liver biopsy: PAS:Glycogenated hepatocytes PAS w diastase: no hyaline globules No stainable iron Does this rule out fatty liver or liver disease?

Liver biopsy:
PAS:Glycogenated hepatocytes 
PAS w diastase: no hyaline globules
No stainable iron
Does this rule out fatty liver or liver disease?

Not all diseases: It rules deposition of iron and carbohydrates. The description does not mention fat. At times biopsy may not contain lesions present elsewhere in the organ. It would be prudent to discuss it with your doctor and better yet with your doctor and the pathologist who reviewed the biopsy. ...Read more

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Can biliary hyperkinesia damage gallbladder, pancreas, liver, or biliary tree? My ultrasound was normal, but ejection fraction=91%.

Yes, biliary: Dyskinesia can cause damage, and it can also be a result of pathology in pancreas, liver or biliary tree. Byt 91% ejection is normal. Consult with a surgeon or GI specialist for specific recommendation. ...Read more

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What distinguishes pancreas, liver, colon, kidney, prostate and gallbladder cancers?

What distinguishes pancreas, liver, colon, kidney, prostate and gallbladder cancers?

Cure varies: Beyond the obvious differences in organ and cell type as well as the various treatment approaches, the most important patient difference is really the chance at cure. Early stage prostate and renal cell (kidney) cancers can be very curable. Even really early stage pancreatic cancers can be quite deadly. ...Read more

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What is the liver biliary atresia?

Biliary atresia: Biliary atresia is a congenital scarring of the biliary ducts. These ducts transport bile made in the liver to the intestine so one can digest fats. The ducts scar and obliterate. Bile then cannot exit the liver which poisons the liver. These infants need corrective surgery before they are 2 months old. ...Read more

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Is liver cirrhosis completely curable?

Is liver cirrhosis completely curable?

No: Some scarring will always remain even if you can remove the original cause (alcohol, hemochromatosis, wilson's, hepatitis b / c, autoimmunity). However, some cirrhotic livers have enough scar regression so that you can have a happy life. ...Read more

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Do gall stones raise liver enzymes?

They may: It is not unusual for patients to have slight elevations in their liver enzymes with gall stones. This is probably caused by sub clinical inflammation in the gall bladder. Significant elevations are seen in acute cholecystitis and elevation of the bilirubin can be due due common duct stones with obstruction. ...Read more

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Is alcohol largely to blame for liver cirrhosis?

Is alcohol largely to blame for liver cirrhosis?

Alcohol & cirrhosis: Cirrhosis is scarring of the liver. It can occur without any alcohol consumption at all. Alcohol can exacerbate another condtion making it progress to cirrhosis more quickly. Most 'true' alcoholics' do not develop cirrhosis without some other condition present. Cirrhosis purely due to alcohol is relatively uncommon. Hepatitis from alcohol can mimic cirrhosis yet fully recover with abstinence. ...Read more

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Upper Abdomen (Definition)

Draw a transverse line through the umbilicus and the upper abdomen includes every part of the belly above this line and below the ...Read more


Dr. Bernard Seif
64 doctors shared insights

Primary Biliary Cirrhosis (Definition)

A condition where the bile ducts of the liver break down. This causes a buildup of bile in the liver, including ...Read more