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Doctor insights on: Eliminate Biliary Cirrhosis

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Is primary biliary cirrhosis hereditary?

Is primary biliary cirrhosis hereditary?

Basically no: There's a pair of genes that carry the ability to develop the disease and these run in families, but it's not inherited like sickle cell, huntington's or some of the other familiar entities. http://www.medicalnewstoday.com/releases/151640.php. ...Read more

Dr. Dariush Saghafi
1 doctor shared a insight

Biliary (Definition)

Biliary means anything related to the production, storage, secretion, or flow of bile, whether in the liver, bile ducts, gallbladder, ...Read more


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What are the tests for biliary cirrhosis?

What are the tests for biliary cirrhosis?

Autoantibody &Biopsy: In addition to abnormal blood tests due to malfunction of liver, patients with primary biliary cirrhosis have peculiar autoantibodies, anti-mitochondrial antibodies. Blood tests and imaging suggest cirrhosis, confirmation requires biopsy (usually needle biopsy) and examination of the tissue by a pathologist. ...Read more

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What exactly is primary biliary cirrhosis?

What exactly is primary biliary cirrhosis?

Liver disease: Primary biliary cirrhosis is an autoimmune liver disease seen most commonly in women in the 4th to 5th decade of life. It generally presents with unexplained itching and occasionally jaundice. It is frequently found on routing screening liver tests which may show an elevated alkaline phosphotase. Though not curable it is treatable and treatment slows the progression to cirrhosis. ...Read more

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What are the symptoms of biliary cirrhosis?

Jaundice & itching: Primary biliary cirrhosis is an autoimmune phenomenon and may be associated with damage to other organs. The prominent symptoms of biliary cirrhosis are jaundice and itching. With progression symptoms of liver failure, e.g., edema, bleeding, ascites etc appear. ...Read more

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How can I treat primary biliary cirrhosis ?

Ursodiol: There is not much available to treat primary biliary cirrhosis, but ursodiol helps normalize the liver enzymes. For other therapies you should discuss with a hepatologist. ...Read more

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Describe the features of biliary cirrhosis.?

Describe the features of biliary cirrhosis.?

Liver failure: There are many things that happen with cirrhosis, depending on how severe it is. These include confusion, bleeding from the GI tract, jaundice, fluid buildup in the belly, increased risk for liver cancer, and other symptoms. ...Read more

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What happens when you have biliary cirrhosis?

What happens when you have biliary cirrhosis?

Liver failure: Biliary cirrhosis causes progressive damage to the liver. There is fibrosis (hardening) of the substance of the liver, increasing pressure in the blood supply, and slowly damaging the cells. Sepending on the cause of cirrhosis, there is very little that will cause reversal of the damage. ...Read more

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If you get biliary cirrhosis, how do you feel?

If you get biliary cirrhosis, how do you feel?

Depends: Some patients with biliary cirrhosis have no symptoms. Others have fatigue and other have severe itching. If you have this condition, you should see your doctor. ...Read more

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What is the cause of primary biliary cirrhosis?

Autoimmune: An autoimmune disorder in which the body attacks it's own liver. ...Read more

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Who is most likely to develop biliary cirrhosis?

Who is most likely to develop biliary cirrhosis?

PBC--who gets it: 90% of pbc patients are female. Age ranges 20-80, but typically patients are 40-60. The disease is world-wide, & affects asians, caucasians, jews, african. Family clustering is common in sisters, twins, daughters, mothers. While environmental factors can't be ignored, a strong immunogenetic background for pbc that runs in families is suggested. Early sxs: fatigue, itching before jaundice, RUQ pain. ...Read more

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What can be done for primary biliary cirrhosis?

Number of things: If caught early, there are medications, particularly ursodeoxycholic acid (actigall) which can slow it down. Preventing and treating complications is also important, especially high pressure in the portal vein, which can be treated with beta blockers (inderal (propranolol) and others) and sometimes surgery. Itching, fatigue and other symptoms can be treated as well, but liver transplant is needed when severe. ...Read more

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Can you tell me about primary biliary cirrhosis?

Liver disease: Chronic disease of the liver from scarring of the biliary ducts. Probably an autoimmune disease. There are medications to help with this disease, but you need close follow up with a GI doc. Good luck. ...Read more

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What can I expect if I have primary biliary cirrhosis?

Maybe liver failure: Primary biliary cirrhosis is an insidious disease that tends to be progressive over time. The small ducts that drain bile from the liver will narrow and prevent adequate drainage of bile to the intestine. The liver will experience damage with years of inadequate bile drainage and eventually severe scarring (cirrhosis) occurs. With cirrhosis, the only option is liver transplantation for best chance. ...Read more

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Has anyone survived primary biliary cirrhosis for long?

Yes: There are some new medications that have been effective for stopping the progression of primary biliary cirrhosis, particularly urso- deoxycholic acid. In addition, liver transplanation can be lifesaving, and patients can live normal lifespans after liver transplantation, although the need for anti- rejection drugs can affect the quality of life and cause complications which shorten life as well. ...Read more

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How does one effectively treat primary biliary cirrhosis?

Not a great answer : Unfortunately, there is no cure. The autoimmune disorder destroys the liver over time. The treatments help to relieve the symptoms (ursodiol, anti-itching meds, anti-inflammatory meds, immune suppressing meds etc.) and if the disease progresses to final stages, liver transplant is the only really treatment. ...Read more

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I know this dude who has biliary cirrhosis. What is that?

PBC in dudes: 90% of pbc patients are female. Age ranges 20-80, but typically patients are 40-60. The disease is world-wide, & affects asians, caucasians, jews, african. Family clustering is common in sisters, twins, daughters, mothers. While environmental factors can't be ignored, a strong immunogenetic background for pbc that runs in families is suggested. Early sxs: fatigue, itching before jaundice, RUQ pain. ...Read more

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How do you know who is most likely to get biliary cirrhosis?

How do you know who is most likely to get biliary cirrhosis?

Risks of getting PBC: 90% of pbc patients are female. Age ranges 20-80, but typically patients are 40-60. The disease is world-wide, & affects asians, caucasians, jews, african. Family clustering is common in sisters, twins, daughters, mothers. While environmental factors can't be ignored, a strong immunogenetic background for pbc that runs in families is suggested. Early sxs: fatigue, itching +/- jaundice, RUQ pain. ...Read more

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What is the definition or description of: Biliary cirrhosis?

Biliary Cirrhosis: Biliary Cirrhosis means cirrhosis due to damage to bile ducts ...Read more

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How will having biliary cirrhosis affect my long-term health?

How will having biliary cirrhosis affect my long-term health?

Bad if untreated: An immuno-genetic disease, of which 90% are female, typically 40-60 years old. The disease affects asians, caucasians, jews, african. Family clustering is common. Early symptoms are fatigue, itching before jaundice, RUQ pain. Untreated pbc leads to progressive liver failure with its sequelae. Advanced age, liver/spleen enlargement, ascites, low albumin, fibrosis, cirrhosis predict worst prognosis. ...Read more

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My sister has biliary cirrhosis. Should I be worried about it?

Family risks for PBC: 90% of pbc patients are female. Age ranges 20-80, but typically patients are 40-60. The disease is world-wide, & affects asians, caucasians, jews, african. Family clustering is common in sisters, twins, daughters, mothers. While environmental factors can't be ignored, a strong immunogenetic background for pbc that runs in families is suggested. Early sxs: fatigue, itching before jaundice, RUQ pain. ...Read more

Upper Abdomen (Definition)

Draw a transverse line through the umbilicus and the upper abdomen includes every part of the belly above this line and below the ...Read more


Dr. Ronald Krauser
63 doctors shared insights

Primary Biliary Cirrhosis (Definition)

A condition where the bile ducts of the liver break down. This causes a buildup of bile in the liver, including ...Read more