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Doctor insights on: Eligard Gnrh Stimulator

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Dr. Lonnie Smith
25 doctors shared insights

Gnrh (Definition)

Gnrh= gonadotropin releasing hormone is a hormone made in the hypothalamus of the brain involved with release of ...Read more


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Why do patients taking gnrh-a lose bone?

Why do patients taking gnrh-a lose bone?

GnRH hormones: While normally gnrh stimulates sex hormones, it achieves this only when it is secreted in bursts by the hypothalamus. When given in injections, it circulates continuously and it suppresses the hormones that in turn stimulate the ovary in women and the testes in men. As a consequence, there is a lack of sex hormones (estradiol in women, testosterone in men, leading to bone loss as in menopause. ...Read more

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What problems are there switching from degarelix to eligard (leuprolide)?

What  problems  are  there switching  from  degarelix to  eligard (leuprolide)?

Not many problems: One problem may be insurance coverage unfortunately but overall symptoms between the two are likely to be similar. Studies have shown perhaps increased effectiveness of degarelix vs Eligard (leuprolide) when treating prostate cancer. ...Read more

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I was told that I had a slight decrease in my bone density while on gnrh-a. Can you explain this?

I was told that I had a slight decrease in my bone density while on gnrh-a. Can you explain this?

Low estrogen: Estrogen is important for building bone and maintaining bone density. When one is on gnrha therapy (lupron) estrogen concentrations are low, and therefore bone is lost. Fortunately, after stopping therapy, bone density tends to return to normal. ...Read more

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Why do FSH levels rise around day 14 of the cycle? Is it just because of the higher GnRH that cause the LH surge?

Why do FSH levels rise around day 14 of the cycle?  Is it just because of the higher GnRH that cause the LH surge?

You asked...: FSH rises because 1) it induces expression of its own receptor and 2) it stimulates E2 production, which also induces expression of more FSH receptors. GnRH is not "higher" or lower, GnRH is pulsatile: the frequency of the pulses is as important (or more) than the pulse amplitude. If this unclear, I suggest consulting an endocrinology text, there is no short version. ...Read more

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Gonadotropin-releasing hormone (gnrh) stimulates what?

Gonadotropin-releasing hormone (gnrh) stimulates what?

FSH,LH: Gnrh stimulates follicle stimulating hormone & luteinizing hormone which stimulates the ovary to produce estrogen and Progesterone which stimulates ovulation which causes increased Progesterone which causes secretory endometrium which prepares the endometrium to allow implantation of a fertilized egg. If no fertilized egg, Progesterone falls which stimulates gnrh to again rise & the cycle repeats. ...Read more

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What is the definition or description of: gnrh?

What is the definition or description of: gnrh?

Pituitary hormone: Gnrh= gonadotropin releasing hormone is a hormone made in the hypothalamus of the brain involved with release of hormones involved with ovulation. ...Read more

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Whats role of gnrh in ovulation?

Whats role of gnrh in ovulation?

GnRH: Fsh and lh stimulated which in turn stimulates production of estrogen and progesteron in proper cycle. ...Read more

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What hormones stimulate the release of gnrh?

What hormones stimulate the release of gnrh?

Insulin: GnRH is stimulated by an increase in insulin (as can be seen in PCOS). An increase in prolactin causes a decrease in GnRH. GnRH is low in early childhood, then is activated in puberty, and has a pulsatile release for normal reproductive function. What exactly initiates puberty is not completely known with biological and environmental factors playing a role. ...Read more

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Do gnrh agonists have side effects?

Do gnrh agonists have side effects?

Absolutely: These drugs can cause a temporary medical menopausal state with all of the associated symptoms, ie, hotflashes, vaginal dryness, sleep disturbances, mood swings, etc. ...Read more

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Can an increase in testosterone decrease gnrh release?

Can an increase in testosterone decrease gnrh release?

Yes: Testosterone (from the testicles) and gnrh (from the hypothalamus) are connected by a feedback mechanism much like the thermostat in one's house. When testosterone levels rise for whatever reason, the hypothalamus decreases its release of gnrh to help bring t back to normal levels and vice versa. ...Read more

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Pain from having hormone injections(gnrh agonist)?

Pain from having hormone injections(gnrh agonist)?

Unlikely: Generally no, not pain unless you mean pain at the injection site. ...Read more

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Is it true that gnrh agonists are good treatments for endometriosis?

Is it true that gnrh agonists are good treatments for endometriosis?

Temporary Relief?: First, one needs to be sure of the diagnosis. It is a surgical diagnosis. Second, these medications create a temporary menopause with numerous side effects including bone loss. Add back hormones may help. That stated, these medications allow for the shrinking of the lesions but they are not removed. Within three months of stopping the medication, the lesions are back with symptoms to follow. ...Read more

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Gonadotropin-releasing hormone (gnrh) stimulates the production what?

Good question: Gnrh would seem by its name to help release gonadotropin. And if used in a certain fashion it could cause the release of gonadotropins (lh, fsh). However when given in a shot and having a sustained effect on the pituitary, it actually suppresses the release of lh and fsh. And this aspect of the medication can be used to help in many situations. ...Read more

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I am taking testosterone suppressant therapy.(eligard). What can allow me to have erections?

ED: There are three drugs: viagra, Levitra (vardenafil) and Cialis that your physician can prescribe. There is also trimix (pge-1) that can be injected into the body of the penis; muse is a suppository that is inserted in the urethra (pge-1); vacuum erection devise(ved). Insertion of a semirigid or inflatable prosthesis could be considered if everything else fails but it requires surgery. Good luck. ...Read more

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What is gnrh hormone?

What is gnrh hormone?

Complicated: Gnrh stands for gonadotropin releasing hornone. It's a neurohormone produced in the hypothalamus (part of the brain). Its release controls the production/release of 2 pituitary hormones called luteinizing hormone (lh) and follicle stimulating hormone (fsh) which in turn regulate and affect your ovary/menstrual periods or in men sperm and testosterone production. ...Read more

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Can you tell me about hormones: gnrh surge--> lh?

Normal: I am not sure what you are asking, but GNRH is a hormone produced by the hypothalamus. It is made in a pulsatile manner normally. This acts on the pituitary gland to cause the release of LH, also in a pulsatile manner. Taking large amounts of GNRH analogs (such as Lupron) initially causes release of LH, but then suppresses further release (thereby turning off testosterone or estrogen production) ...Read more

Dr. Eric Weisman
152 doctors shared insights

Leuprolide Acetate (Definition)

Leuprolide acetate is a GnRH stimulator which is a kind of women's ...Read more


Dr. Sandra Eleczko
9 doctors shared insights

Eligard (Definition)

Eligard is a GnRH stimulator which is a kind of women's ...Read more